These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 38796131)

  • 1. Identification of the interfacial regions in misfolded transthyretin oligomers.
    Dasari AKR; Coats MF; Ali AB; Lim KH
    Biochim Biophys Acta Proteins Proteom; 2024 Sep; 1872(5):141027. PubMed ID: 38796131
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of the CD Loop by Enzymatic Cleavage Promotes the Formation of Toxic Transthyretin Oligomers through a Common Transthyretin Misfolding Pathway.
    Dasari AKR; Arreola J; Michael B; Griffin RG; Kelly JW; Lim KH
    Biochemistry; 2020 Jun; 59(25):2319-2327. PubMed ID: 32500705
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Toxic Misfolded Transthyretin Oligomers with Different Molecular Conformations Formed through Distinct Oligomerization Pathways.
    Dasari AKR; Yi S; Coats MF; Wi S; Lim KH
    Biochemistry; 2022 Nov; 61(21):2358-2365. PubMed ID: 36219173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two distinct aggregation pathways in transthyretin misfolding and amyloid formation.
    Dasari AKR; Hung I; Gan Z; Lim KH
    Biochim Biophys Acta Proteins Proteom; 2019 Mar; 1867(3):344-349. PubMed ID: 30366153
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.
    Jesus CS; Almeida ZL; Vaz DC; Faria TQ; Brito RM
    Int J Mol Sci; 2016 Aug; 17(9):. PubMed ID: 27589730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
    Pinheiro F; Varejão N; Esperante S; Santos J; Velázquez-Campoy A; Reverter D; Pallarès I; Ventura S
    FEBS J; 2021 Jan; 288(1):310-324. PubMed ID: 32324953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potentially amyloidogenic conformational intermediates populate the unfolding landscape of transthyretin: insights from molecular dynamics simulations.
    Rodrigues JR; Simões CJ; Silva CG; Brito RM
    Protein Sci; 2010 Feb; 19(2):202-19. PubMed ID: 19937650
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis.
    Sörgjerd K; Ghafouri B; Jonsson BH; Kelly JW; Blond SY; Hammarström P
    J Mol Biol; 2006 Feb; 356(2):469-82. PubMed ID: 16376939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploration of the Misfolding Mechanism of Transthyretin Monomer: Insights from Hybrid-Resolution Simulations and Markov State Model Analysis.
    Zhou S; Cheng J; Yang T; Ma M; Zhang W; Yuan S; Lo GV; Dou Y
    Biomolecules; 2019 Dec; 9(12):. PubMed ID: 31861226
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.
    Sant'Anna R; Braga C; Varejão N; Pimenta KM; Graña-Montes R; Alves A; Cortines J; Cordeiro Y; Ventura S; Foguel D
    J Biol Chem; 2014 Oct; 289(41):28324-37. PubMed ID: 25086037
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Uncovering the Mechanism of Aggregation of Human Transthyretin.
    Saelices L; Johnson LM; Liang WY; Sawaya MR; Cascio D; Ruchala P; Whitelegge J; Jiang L; Riek R; Eisenberg DS
    J Biol Chem; 2015 Nov; 290(48):28932-43. PubMed ID: 26459562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The sequence-dependent unfolding pathway plays a critical role in the amyloidogenicity of transthyretin.
    Yang M; Yordanov B; Levy Y; Brüschweiler R; Huo S
    Biochemistry; 2006 Oct; 45(39):11992-2002. PubMed ID: 17002298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation.
    Lashuel HA; Lai Z; Kelly JW
    Biochemistry; 1998 Dec; 37(51):17851-64. PubMed ID: 9922152
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific disruption of transthyretin(105-115) fibrilization using "stabilizing" inhibitors of transthyretin amyloidogenesis.
    Liang Y; Ore MO; Morin S; Wilson DJ
    Biochemistry; 2012 Apr; 51(16):3523-30. PubMed ID: 22482799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Why is Leu55-->Pro55 transthyretin variant the most amyloidogenic: insights from molecular dynamics simulations of transthyretin monomers.
    Yang M; Lei M; Huo S
    Protein Sci; 2003 Jun; 12(6):1222-31. PubMed ID: 12761393
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trapping the monomer of a non-amyloidogenic variant of transthyretin: exploring its possible use as a therapeutic strategy against transthyretin amyloidogenic diseases.
    Palhano FL; Leme LP; Busnardo RG; Foguel D
    J Biol Chem; 2009 Jan; 284(3):1443-53. PubMed ID: 18984591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clusterin regulates transthyretin amyloidosis.
    Lee KW; Lee DH; Son H; Kim YS; Park JY; Roh GS; Kim HJ; Kang SS; Cho GJ; Choi WS
    Biochem Biophys Res Commun; 2009 Oct; 388(2):256-60. PubMed ID: 19664600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers.
    Dasari AKR; Hughes RM; Wi S; Hung I; Gan Z; Kelly JW; Lim KH
    Sci Rep; 2019 Jan; 9(1):33. PubMed ID: 30631096
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy.
    Taguchi K; Jono H; Kugimiya-Taguchi T; Nagao S; Su Y; Yamasaki K; Mizuguchi M; Maruyama T; Ando Y; Otagiri M
    Life Sci; 2013 Dec; 93(25-26):1017-22. PubMed ID: 24211615
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis.
    Ferreira N; Saraiva MJ; Almeida MR
    Int J Mol Sci; 2019 Mar; 20(6):. PubMed ID: 30875761
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.