BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 38798458)

  • 1. eIF2α phosphorylation evokes dystonia-like movements with D2-receptor and cholinergic origin and abnormal neuronal connectivity.
    Lewis SA; Forstrom J; Tavani J; Schafer R; Tiede Z; Padilla-Lopez SR; Kruer MC
    bioRxiv; 2024 May; ():. PubMed ID: 38798458
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.
    Rittiner JE; Caffall ZF; Hernández-Martinez R; Sanderson SM; Pearson JL; Tsukayama KK; Liu AY; Xiao C; Tracy S; Shipman MK; Hickey P; Johnson J; Scott B; Stacy M; Saunders-Pullman R; Bressman S; Simonyan K; Sharma N; Ozelius LJ; Cirulli ET; Calakos N
    Neuron; 2016 Dec; 92(6):1238-1251. PubMed ID: 27939583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
    Beauvais G; Bode NM; Watson JL; Wen H; Glenn KA; Kawano H; Harata NC; Ehrlich ME; Gonzalez-Alegre P
    J Neurosci; 2016 Oct; 36(40):10245-10256. PubMed ID: 27707963
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.
    Beauvais G; Rodriguez-Losada N; Ying L; Zakirova Z; Watson JL; Readhead B; Gadue P; French DL; Ehrlich ME; Gonzalez-Alegre P
    Neuroscience; 2018 Feb; 371():455-468. PubMed ID: 29289717
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia.
    Tassone A; Martella G; Meringolo M; Vanni V; Sciamanna G; Ponterio G; Imbriani P; Bonsi P; Pisani A
    Mov Disord; 2021 Dec; 36(12):2768-2779. PubMed ID: 34173686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diverse Mechanisms Lead to Common Dysfunction of Striatal Cholinergic Interneurons in Distinct Genetic Mouse Models of Dystonia.
    Eskow Jaunarajs KL; Scarduzio M; Ehrlich ME; McMahon LL; Standaert DG
    J Neurosci; 2019 Sep; 39(36):7195-7205. PubMed ID: 31320448
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia.
    Martella G; Maltese M; Nisticò R; Schirinzi T; Madeo G; Sciamanna G; Ponterio G; Tassone A; Mandolesi G; Vanni V; Pignatelli M; Bonsi P; Pisani A
    Neurobiol Dis; 2014 May; 65():124-32. PubMed ID: 24503369
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Decreased number of striatal cholinergic interneurons and motor deficits in dopamine receptor 2-expressing-cell-specific Dyt1 conditional knockout mice.
    Yokoi F; Oleas J; Xing H; Liu Y; Dexter KM; Misztal C; Gerard M; Efimenko I; Lynch P; Villanueva M; Alsina R; Krishnaswamy S; Vaillancourt DE; Li Y
    Neurobiol Dis; 2020 Feb; 134():104638. PubMed ID: 31618684
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell-specific Dyt1 ∆GAG knock-in to basal ganglia and cerebellum reveal differential effects on motor behavior and sensorimotor network function.
    Wilkes BJ; Adury RZ; Berryman D; Concepcion LR; Liu Y; Yokoi F; Maugee C; Li Y; Vaillancourt DE
    Exp Neurol; 2023 Sep; 367():114471. PubMed ID: 37321386
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.
    Martella G; Tassone A; Sciamanna G; Platania P; Cuomo D; Viscomi MT; Bonsi P; Cacci E; Biagioni S; Usiello A; Bernardi G; Sharma N; Standaert DG; Pisani A
    Brain; 2009 Sep; 132(Pt 9):2336-49. PubMed ID: 19641103
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Strength of cholinergic tone dictates the polarity of dopamine D2 receptor modulation of striatal cholinergic interneuron excitability in DYT1 dystonia.
    Scarduzio M; Zimmerman CN; Jaunarajs KL; Wang Q; Standaert DG; McMahon LL
    Exp Neurol; 2017 Sep; 295():162-175. PubMed ID: 28587876
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reversal of motor-skill transfer impairment by trihexyphenidyl and reduction of dorsolateral striatal cholinergic interneurons in
    Yokoi F; Dang MT; Zhang L; Dexter KM; Efimenko I; Krishnaswamy S; Villanueva M; Misztal CI; Gerard M; Lynch P; Li Y
    IBRO Neurosci Rep; 2021 Dec; 11():1-7. PubMed ID: 34189496
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia.
    Eskow Jaunarajs KL; Bonsi P; Chesselet MF; Standaert DG; Pisani A
    Prog Neurobiol; 2015 Apr; 127-128():91-107. PubMed ID: 25697043
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Optogenetic augmentation of the hypercholinergic endophenotype in DYT1 knock-in mice induced erratic hyperactive movements but not dystonia.
    Richter F; Bauer A; Perl S; Schulz A; Richter A
    EBioMedicine; 2019 Mar; 41():649-658. PubMed ID: 30819512
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo optogenetic inhibition of striatal parvalbumin-reactive interneurons induced genotype-specific changes in neuronal activity without dystonic signs in male DYT1 knock-in mice.
    Schulz A; Richter F; Richter A
    J Neurosci Res; 2023 Apr; 101(4):448-463. PubMed ID: 36546658
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigating the role of striatal dopamine receptor 2 in motor coordination and balance: Insights into the pathogenesis of DYT1 dystonia.
    Liu Y; Xing H; Yokoi F; Vaillancourt DE; Li Y
    Behav Brain Res; 2021 Apr; 403():113137. PubMed ID: 33476687
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tor1a+/- mice develop dystonia-like movements via a striatal dopaminergic dysregulation triggered by peripheral nerve injury.
    Ip CW; Isaias IU; Kusche-Tekin BB; Klein D; Groh J; O'Leary A; Knorr S; Higuchi T; Koprich JB; Brotchie JM; Toyka KV; Reif A; Volkmann J
    Acta Neuropathol Commun; 2016 Oct; 4(1):108. PubMed ID: 27716431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amphetamine elevates phosphorylation of eukaryotic initiation factor 2α (eIF2α) in the rat forebrain via activating dopamine D1 and D2 receptors.
    Xue B; Fitzgerald CA; Jin DZ; Mao LM; Wang JQ
    Brain Res; 2016 Sep; 1646():459-466. PubMed ID: 27338925
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of eIF2α in Neuronal Injury Induced by High Glucose and the Protective Mechanism of Resveratrol.
    Zhang L; Zhi K; Su Y; Peng W; Meng X
    Mol Neurobiol; 2023 Oct; 60(10):6043-6059. PubMed ID: 37410333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Negative allosteric modulation of mGlu5 receptor rescues striatal D2 dopamine receptor dysfunction in rodent models of DYT1 dystonia.
    Sciamanna G; Ponterio G; Tassone A; Maltese M; Madeo G; Martella G; Poli S; Schirinzi T; Bonsi P; Pisani A
    Neuropharmacology; 2014 Oct; 85():440-50. PubMed ID: 24951854
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.