These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 38803590)

  • 41. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells.
    Wang X; Yu Y; Wang P; Yang K; Wang Y; Yan L; Zhong XB; Zhang L
    Drug Metab Dispos; 2022 May; 50(5):704-715. PubMed ID: 34949673
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 43. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
    Ma X; Cheung C; Krausz KW; Shah YM; Wang T; Idle JR; Gonzalez FJ
    Drug Metab Dispos; 2008 Dec; 36(12):2506-12. PubMed ID: 18799805
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway.
    Awortwe C; Manda VK; Avonto C; Khan SI; Khan IA; Walker LA; Bouic PJ; Rosenkranz B
    Xenobiotica; 2015 Mar; 45(3):218-29. PubMed ID: 25377539
    [TBL] [Abstract][Full Text] [Related]  

  • 45. In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors.
    Zhang W; Purchio A; Chen K; Burns SM; Contag CH; Contag PR
    Biochem Pharmacol; 2003 Jun; 65(11):1889-96. PubMed ID: 12781341
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation.
    Sivertsson L; Edebert I; Palmertz MP; Ingelman-Sundberg M; Neve EP
    Mol Pharmacol; 2013 Mar; 83(3):659-70. PubMed ID: 23264496
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
    El-Sankary W; Bombail V; Gibson GG; Plant N
    Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
    [TBL] [Abstract][Full Text] [Related]  

  • 49. A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
    Raucy J; Warfe L; Yueh MF; Allen SW
    J Pharmacol Exp Ther; 2002 Oct; 303(1):412-23. PubMed ID: 12235278
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis (p-chlorophenyl)ethane.
    Medina-Díaz IM; Arteaga-Illán G; de León MB; Cisneros B; Sierra-Santoyo A; Vega L; Gonzalez FJ; Elizondo G
    Drug Metab Dispos; 2007 Jan; 35(1):95-102. PubMed ID: 17035600
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor.
    Harmsen S; Meijerman I; Beijnen JH; Schellens JH
    Cancer Chemother Pharmacol; 2009 Jun; 64(1):35-43. PubMed ID: 18839173
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [TBL] [Abstract][Full Text] [Related]  

  • 54. A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
    Trubetskoy O; Marks B; Zielinski T; Yueh MF; Raucy J
    AAPS J; 2005 Mar; 7(1):E6-13. PubMed ID: 16146350
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Extracts of Immature Orange
    Okada N; Murakami A; Urushizaki S; Matsuda M; Kawazoe K; Ishizawa K
    Front Pharmacol; 2017; 8():84. PubMed ID: 28270768
    [TBL] [Abstract][Full Text] [Related]  

  • 56. U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells.
    Smutny T; Bitman M; Urban M; Dubecka M; Vrzal R; Dvorak Z; Pavek P
    Arch Toxicol; 2014 Dec; 88(12):2243-59. PubMed ID: 24819614
    [TBL] [Abstract][Full Text] [Related]  

  • 57. A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease.
    Woolsey SJ; Beaton MD; Mansell SE; Leon-Ponte M; Yu J; Pin CL; Adams PC; Kim RB; Tirona RG
    Mol Pharmacol; 2016 Oct; 90(4):437-46. PubMed ID: 27482056
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Gene Expression Profiling of 1α,25(OH)
    Pavek P; Dusek J; Smutny T; Lochman L; Kucera R; Skoda J; Smutna L; Kamaraj R; Soucek P; Vrzal R; Dvorak Z
    Mol Nutr Food Res; 2022 May; 66(9):e2200070. PubMed ID: 35184385
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway.
    Ding X; Staudinger JL
    J Pharmacol Exp Ther; 2005 Feb; 312(2):849-56. PubMed ID: 15459237
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.
    Dong H; Lin W; Wu J; Chen T
    BMC Biochem; 2010 Jun; 11():23. PubMed ID: 20553580
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.