These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats. Mahmoud AM; Hozayen WG; Ramadan SM Biomed Pharmacother; 2017 Oct; 94():280-291. PubMed ID: 28763751 [TBL] [Abstract][Full Text] [Related]
5. The enteroprotective effect of nifuroxazide against methotrexate-induced intestinal injury involves co-activation of PPAR-γ, SIRT1, Nrf2, and suppression of NF-κB and JAK1/STAT3 signals. Abd-Alhameed EK; Azouz AA; Abo-Youssef AM; Ali FEM Int Immunopharmacol; 2024 Jan; 127():111298. PubMed ID: 38070469 [TBL] [Abstract][Full Text] [Related]
7. The Mechanisms of the Anti-Inflammatory and Anti-Apoptotic Effects of Omega-3 Polyunsaturated Fatty Acids during Methotrexate-Induced Intestinal Damage in Cell Line and in a Rat Model. Koppelmann T; Pollak Y; Ben-Shahar Y; Gorelik G; Sukhotnik I Nutrients; 2021 Mar; 13(3):. PubMed ID: 33801889 [No Abstract] [Full Text] [Related]
8. Zinc and L-carnitine combination with or without methotrexate prevents intestinal toxicity during arthritis treatment via Nrf2/Sirt1/Foxo3 pathways: an In vivo and molecular docking approach. Katturajan R; Evan Prince S Inflammopharmacology; 2023 Oct; 31(5):2599-2614. PubMed ID: 37405586 [TBL] [Abstract][Full Text] [Related]
9. Involvement of Nrf2/HO-1 antioxidant signaling and NF-κB inflammatory response in the potential protective effects of vincamine against methotrexate-induced nephrotoxicity in rats: cross talk between nephrotoxicity and neurotoxicity. Shalaby YM; Menze ET; Azab SS; Awad AS Arch Toxicol; 2019 May; 93(5):1417-1431. PubMed ID: 31020375 [TBL] [Abstract][Full Text] [Related]
10. Taurine attenuated methotrexate-induced intestinal injury by regulating NF-κB/iNOS and Keap1/Nrf2/HO-1 signals. Hassanein EHM; Althagafy HS; Atwa AM; Kozman MR; Kotb El-Sayed MI; Soubh AA Life Sci; 2022 Dec; 311(Pt A):121180. PubMed ID: 36370869 [TBL] [Abstract][Full Text] [Related]
11. Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats. Fayez AM; Zakaria S; Moustafa D Biomed Pharmacother; 2018 Sep; 105():428-433. PubMed ID: 29879626 [TBL] [Abstract][Full Text] [Related]
12. Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological analysis. Sayed AM; Hassanein EHM; Ali FEM; Omar ZMM; Rashwan EK; Mohammedsaleh ZM; Abd El-Ghafar OAM Life Sci; 2021 Nov; 284():119911. PubMed ID: 34450167 [TBL] [Abstract][Full Text] [Related]
13. Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways. Hassanein EHM; Kamel EO; Ali FEM; Ahmed MA Life Sci; 2021 Sep; 281():119754. PubMed ID: 34174323 [TBL] [Abstract][Full Text] [Related]
14. Ellagic acid reduces methotrexate-induced apoptosis and mitochondrial dysfunction via up-regulating Nrf2 expression and inhibiting the IĸBα/NFĸB in rats. Ebrahimi R; Sepand MR; Seyednejad SA; Omidi A; Akbariani M; Gholami M; Sabzevari O Daru; 2019 Dec; 27(2):721-733. PubMed ID: 31736017 [TBL] [Abstract][Full Text] [Related]