104 related articles for article (PubMed ID: 38833640)
1. Cellular pharmacokinetic of methotrexate and its modulation by folylpolyglutamate synthetase and γ-glutamyl hydrolase in tumor cells.
Tang F; Zou L; Chen J; Meng F
PLoS One; 2024; 19(6):e0302663. PubMed ID: 38833640
[TBL] [Abstract][Full Text] [Related]
2. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
Longo GS; Gorlick R; Tong WP; Lin S; Steinherz P; Bertino JR
Oncol Res; 1997; 9(5):259-63. PubMed ID: 9306433
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of Intracellular Metabolism of Methotrexate in Hepatocytes and Embryonic Kidney Cells based on Folylpolyglutamate Synthetase and Gamma-Glutamyl Hydrolase Expression.
Jiang H; Yang J; Hou Y; Zhang K; Ren Y; Huang J; Li H; Cai T; Ouyang Z; Zhao J; Yu P
Curr Drug Metab; 2023; 24(2):139-147. PubMed ID: 37038713
[TBL] [Abstract][Full Text] [Related]
4. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
[TBL] [Abstract][Full Text] [Related]
5. Studies on the intracellular accumulation process of methotrexate and its correlation with the key protein using an LC-MS/MS method: a novel way to realize prospective individualized medication.
Ouyang Z; Huang J; Ren Y; Li H; Ding Y; Zhang K; Jiang L; Yu P
Anal Bioanal Chem; 2021 Mar; 413(7):1799-1807. PubMed ID: 33564926
[TBL] [Abstract][Full Text] [Related]
6. Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.
Rots MG; Pieters R; Peters GJ; Noordhuis P; van Zantwijk CH; Kaspers GJ; Hählen K; Creutzig U; Veerman AJ; Jansen G
Blood; 1999 Mar; 93(5):1677-83. PubMed ID: 10029597
[TBL] [Abstract][Full Text] [Related]
7. Effects of overexpression of gamma-Glutamyl hydrolase on methotrexate metabolism and resistance.
Cole PD; Kamen BA; Gorlick R; Banerjee D; Smith AK; Magill E; Bertino JR
Cancer Res; 2001 Jun; 61(11):4599-604. PubMed ID: 11389096
[TBL] [Abstract][Full Text] [Related]
8. Methotrexate intracellular disposition in acute lymphoblastic leukemia: a mathematical model of gamma-glutamyl hydrolase activity.
Panetta JC; Wall A; Pui CH; Relling MV; Evans WE
Clin Cancer Res; 2002 Jul; 8(7):2423-9. PubMed ID: 12114448
[TBL] [Abstract][Full Text] [Related]
9. Folylpolyglutamate synthase is a major determinant of intracellular methotrexate polyglutamates in patients with rheumatoid arthritis.
Yamamoto T; Shikano K; Nanki T; Kawai S
Sci Rep; 2016 Oct; 6():35615. PubMed ID: 27752107
[TBL] [Abstract][Full Text] [Related]
10. Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.
Panetta JC; Sparreboom A; Pui CH; Relling MV; Evans WE
PLoS Comput Biol; 2010 Dec; 6(12):e1001019. PubMed ID: 21152005
[TBL] [Abstract][Full Text] [Related]
11. Rapid decline in folylpolyglutamate synthetase activity and gene expression during maturation of HL-60 cells. Nature of the effect, impact on folate compound polyglutamate pools, and evidence for programmed down-regulation during maturation.
Egan MG; Sirlin S; Rumberger BG; Garrow TA; Shane B; Sirotnak FM
J Biol Chem; 1995 Mar; 270(10):5462-8. PubMed ID: 7890662
[TBL] [Abstract][Full Text] [Related]
12. Do SNPs in folate pharmacokinetic pathway alter levels of intracellular methotrexate polyglutamates and affect response? A prospective study in Indian patients.
Sandhu A; Ahmad S; Kaur J; Bhatnagar A; Dhawan V; Dhir V
Clin Rheumatol; 2018 Dec; 37(12):3221-3228. PubMed ID: 30022368
[TBL] [Abstract][Full Text] [Related]
13. Role of folylpolyglutamate synthetase in the regulation of methotrexate polyglutamate formation in H35 hepatoma cells.
Johnson TB; Nair MG; Galivan J
Cancer Res; 1988 May; 48(9):2426-31. PubMed ID: 2451560
[TBL] [Abstract][Full Text] [Related]
14. The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cells.
Takemura Y; Kobayashi H; Gibson W; Kimbell R; Miyachi H; Jackman AL
Int J Cancer; 1996 Mar; 66(1):29-36. PubMed ID: 8608962
[TBL] [Abstract][Full Text] [Related]
15. Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation.
Gorlick R; Cole P; Banerjee D; Longo G; Li WW; Hochhauser D; Bertino JR
Adv Exp Med Biol; 1999; 457():543-50. PubMed ID: 10500832
[TBL] [Abstract][Full Text] [Related]
16. Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.
Leclerc GJ; Mou C; Leclerc GM; Mian AM; Barredo JC
Leukemia; 2010 Mar; 24(3):552-62. PubMed ID: 20072153
[TBL] [Abstract][Full Text] [Related]
17. Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients.
van der Straaten RJ; Wessels JA; de Vries-Bouwstra JK; Goekoop-Ruiterman YP; Allaart CF; Bogaartz J; Tiller M; Huizinga TW; Guchelaar HJ
Pharmacogenomics; 2007 Feb; 8(2):141-50. PubMed ID: 17286537
[TBL] [Abstract][Full Text] [Related]
18. Determinants of erythrocyte methotrexate polyglutamate levels in rheumatoid arthritis.
den Boer E; de Rotte MC; Pluijm SM; Heil SG; Hazes JM; de Jonge R
J Rheumatol; 2014 Nov; 41(11):2167-78. PubMed ID: 25225283
[TBL] [Abstract][Full Text] [Related]
19. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
[TBL] [Abstract][Full Text] [Related]
20. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.
Barredo JC; Synold TW; Laver J; Relling MV; Pui CH; Priest DG; Evans WE
Blood; 1994 Jul; 84(2):564-9. PubMed ID: 7517720
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
