These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 38834378)

  • 1. Bioisosterism in drug discovery.
    Chatzopoulou M
    Bioorg Med Chem; 2024 Jun; 108():117758. PubMed ID: 38834378
    [No Abstract]   [Full Text] [Related]  

  • 2. Bioisosterism in Drug Discovery and Development - An Overview.
    Jayashree BS; Nikhil PS; Paul S
    Med Chem; 2022; 18(9):915-925. PubMed ID: 35086456
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bioisosterism: 1,2,4-Oxadiazole Rings.
    Camci M; Karali N
    ChemMedChem; 2023 May; 18(9):e202200638. PubMed ID: 36772857
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recent Scaffold Hopping Applications in Central Nervous System Drug Discovery.
    Callis TB; Garrett TR; Montgomery AP; Danon JJ; Kassiou M
    J Med Chem; 2022 Oct; 65(20):13483-13504. PubMed ID: 36206553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of Multifunctional Spirocyclic Azetidines and Their Application in Drug Discovery.
    Kirichok AA; Shton IO; Pishel IM; Zozulya SA; Borysko PO; Kubyshkin V; Zaporozhets OA; Tolmachev AA; Mykhailiuk PK
    Chemistry; 2018 Apr; 24(21):5444-5449. PubMed ID: 29338097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Lead compound optimization strategy (1)--changing metabolic pathways and optimizing metabolism stability].
    Wang J; Liu H
    Yao Xue Xue Bao; 2013 Oct; 48(10):1521-31. PubMed ID: 24417078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemoisosterism in the proteome.
    Jalencas X; Mestres J
    J Chem Inf Model; 2013 Feb; 53(2):279-92. PubMed ID: 23312010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of carbazole derivatives as novel allosteric MEK inhibitors by pharmacophore modeling and virtual screening.
    Xi D; Niu Y; Li H; Noha SM; Temml V; Schuster D; Wang C; Xu F; Xu P
    Eur J Med Chem; 2019 Sep; 178():802-817. PubMed ID: 31252285
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Lead compound optimization strategy (2)--structure optimization strategy for reducing toxicity risks in drug design].
    Liu HL; Wang J; Lin DZ; Liu H
    Yao Xue Xue Bao; 2014 Jan; 49(1):1-15. PubMed ID: 24783499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In Silico Laboratory: Tools for Similarity-Based Drug Discovery.
    Lešnik S; Konc J
    Methods Mol Biol; 2020; 2089():1-28. PubMed ID: 31773644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arylazolyl(azinyl)thioacetanilides: Part 19: Discovery of Novel Substituted Imidazo[4,5-b]pyridin-2-ylthioacetanilides as Potent HIV NNRTIs Via a Structure-based Bioisosterism Approach.
    Li X; Huang B; Zhou Z; Gao P; Pannecouque C; Daelemans D; De Clercq E; Zhan P; Liu X
    Chem Biol Drug Des; 2016 Aug; 88(2):241-53. PubMed ID: 26914186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Translational role of natural coumarins and their derivatives as anticancer agents.
    Menezes JC; Diederich M
    Future Med Chem; 2019 May; 11(9):1057-1082. PubMed ID: 31140865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural modification aimed for improving solubility of lead compounds in early phase drug discovery.
    Das B; Baidya ATK; Mathew AT; Yadav AK; Kumar R
    Bioorg Med Chem; 2022 Feb; 56():116614. PubMed ID: 35033884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Strategies in Medicinal Chemistry to Discover New Hit Compounds against Ebola Virus: Challenges and Perspectives in Drug Discovery.
    Dos Santos Nascimento IJ; da Silva Santos-Júnior PF; de Araújo-Júnior JX; da Silva-Júnior EF
    Mini Rev Med Chem; 2022; 22(22):2896-2924. PubMed ID: 35379146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tetrazoles via Multicomponent Reactions.
    Neochoritis CG; Zhao T; Dömling A
    Chem Rev; 2019 Feb; 119(3):1970-2042. PubMed ID: 30707567
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery and Optimization of Novel 5-Indolyl-7-arylimidazo[1,2-a]pyridine-8-carbonitrile Derivatives as Potent Antitubulin Agents Targeting Colchicine-binding Site.
    Zhai X; Wang X; Wang J; Liu J; Zuo D; Jiang N; Zeng T; Yang X; Jing T; Gong P
    Sci Rep; 2017 Feb; 7():43398. PubMed ID: 28240326
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant.
    de Souza GA; da Silva SJ; Del Cistia CN; Pitasse-Santos P; Pires LO; Passos YM; Cordeiro Y; Cardoso CM; Castro RN; Sant'Anna CMR; Kümmerle AE
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):631-637. PubMed ID: 30727776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recent Advances in Structural Modification Strategies for Lead Optimization of Tyrosine Kinase Inhibitors to Explore Novel Anticancer Agents.
    Azimian F; Dastmalchi S
    Curr Med Chem; 2023; 30(24):2734-2761. PubMed ID: 36125833
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biological evaluation of sulfonate and sulfate analogues of lithocholic acid: A bioisosterism-guided approach towards the discovery of potential sialyltransferase inhibitors for antimetastatic study.
    Perez SJLP; Chen CL; Chang TT; Li WS
    Bioorg Med Chem Lett; 2024 Jun; 105():129760. PubMed ID: 38641151
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioisosteric Replacements Extracted from High-Quality Structures in the Protein Databank.
    Seddon MP; Cosgrove DA; Gillet VJ
    ChemMedChem; 2018 Mar; 13(6):607-613. PubMed ID: 29314719
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.