BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 38844493)

  • 21. Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents.
    Eldehna WM; Abo-Ashour MF; Nocentini A; El-Haggar RS; Bua S; Bonardi A; Al-Rashood ST; Hassan GS; Gratteri P; Abdel-Aziz HA; Supuran CT
    Eur J Med Chem; 2019 Jan; 162():147-160. PubMed ID: 30445264
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII.
    Kumar S; Ceruso M; Tuccinardi T; Supuran CT; Sharma PK
    Bioorg Med Chem; 2016 Jul; 24(13):2907-2913. PubMed ID: 27166574
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of first-in-class multi-target adenosine A
    Ceni C; Catarzi D; Varano F; Ben DD; Marucci G; Buccioni M; Volpini R; Angeli A; Nocentini A; Gratteri P; Supuran CT; Colotta V
    Eur J Med Chem; 2020 Sep; 201():112478. PubMed ID: 32659606
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide - A new caspase-activating proapoptotic agent.
    Dar'in D; Kantin G; Kalinin S; Sharonova T; Bunev A; Ostapenko GI; Nocentini A; Sharoyko V; Supuran CT; Krasavin M
    Eur J Med Chem; 2021 Oct; 222():113589. PubMed ID: 34147910
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids.
    Singh P; Swain B; Thacker PS; Sigalapalli DK; Purnachander Yadav P; Angeli A; Supuran CT; Arifuddin M
    Bioorg Chem; 2020 Jun; 99():103839. PubMed ID: 32289586
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel sulfonamide-containing 2-indolinones that selectively inhibit tumor-associated alpha carbonic anhydrases.
    Karalı N; Akdemir A; Göktaş F; Eraslan Elma P; Angeli A; Kızılırmak M; Supuran CT
    Bioorg Med Chem; 2017 Jul; 25(14):3714-3718. PubMed ID: 28545816
    [TBL] [Abstract][Full Text] [Related]  

  • 27. S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.
    El-Azab AS; Abdel-Aziz AA; Bua S; Nocentini A; AlSaif NA; Alanazi MM; El-Gendy MA; Ahmed HEA; Supuran CT
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):733-743. PubMed ID: 32189526
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents.
    Hao S; Cheng X; Wang X; An R; Xu H; Guo M; Li C; Wang Y; Hou Z; Guo C
    Bioorg Chem; 2020 Nov; 104():104237. PubMed ID: 32911194
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide based thiosemicarbazides as potent and selective inhibitors of tumor-associated human carbonic anhydrase IX and XII: Synthesis, cytotoxicity, and molecular modelling studies.
    Demir-Yazıcı K; Trawally M; Bua S; Öztürk-Civelek D; Akdemir A; Supuran CT; Güzel-Akdemir Ö
    Bioorg Chem; 2024 Mar; 144():107096. PubMed ID: 38290186
    [TBL] [Abstract][Full Text] [Related]  

  • 30. New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment.
    El-Azab AS; Abdel-Aziz AA; Bua S; Nocentini A; AlSaif NA; Almehizia AA; Alanazi MM; Hefnawy MM; Supuran CT
    Eur J Med Chem; 2019 Nov; 181():111573. PubMed ID: 31394463
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties.
    Saied S; Shaldam M; Elbadawi MM; Giovannuzzi S; Nocentini A; Almahli H; Salem R; Ibrahim TM; Supuran CT; Eldehna WM
    Eur J Med Chem; 2023 Nov; 259():115707. PubMed ID: 37556946
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity.
    Soliman AM; Ghorab MM; Bua S; Supuran CT
    Eur J Med Chem; 2020 Aug; 200():112449. PubMed ID: 32485534
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes.
    Gul HI; Yamali C; Bulbuller M; Kirmizibayrak PB; Gul M; Angeli A; Bua S; Supuran CT
    Bioorg Chem; 2018 Aug; 78():290-297. PubMed ID: 29621641
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.
    Said MA; Eldehna WM; Nocentini A; Fahim SH; Bonardi A; Elgazar AA; Kryštof V; Soliman DH; Abdel-Aziz HA; Gratteri P; Abou-Seri SM; Supuran CT
    Eur J Med Chem; 2020 Mar; 189():112019. PubMed ID: 31972394
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX.
    Allam HA; Fahim SH; F Abo-Ashour M; Nocentini A; Elbakry ME; Abdelrahman MA; Eldehna WM; Ibrahim HS; Supuran CT
    Eur J Med Chem; 2019 Oct; 179():547-556. PubMed ID: 31276899
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives.
    Awadallah FM; El-Waei TA; Hanna MM; Abbas SE; Ceruso M; Oz BE; Guler OO; Supuran CT
    Eur J Med Chem; 2015; 96():425-35. PubMed ID: 25912674
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII.
    Chandak N; Ceruso M; Supuran CT; Sharma PK
    Bioorg Med Chem; 2016 Jul; 24(13):2882-2886. PubMed ID: 27137360
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors.
    Shaldam MA; Almahli H; Angeli A; Badi RM; Khaleel EF; Zain-Alabdeen AI; Elsayed ZM; Elkaeed EB; Salem R; Supuran CT; Eldehna WM; Tawfik HO
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2203389. PubMed ID: 37122176
    [TBL] [Abstract][Full Text] [Related]  

  • 39. New Pyridinium Salt Derivatives of 2-(Hydrazinocarbonyl)-3-phenyl-1H-indole-5- sulfonamide as Selective Inhibitors of Tumour-Related Human Carbonic Anhydrase Isoforms IX and XII.
    Güzel-Akdemir Ö; Demir-Yazıcı K; Vullo D; Supuran CT; Akdemir A
    Anticancer Agents Med Chem; 2022; 22(14):2637-2646. PubMed ID: 35135455
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis.
    Abdelrahman MA; Ibrahim HS; Nocentini A; Eldehna WM; Bonardi A; Abdel-Aziz HA; Gratteri P; Abou-Seri SM; Supuran CT
    Eur J Med Chem; 2021 Jan; 209():112897. PubMed ID: 33038795
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.