BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 38851658)

  • 1. Design, spectroscopic characterizations, and biological investigation of oxospiro[chromine-4,3-indolene]-based compounds as promising antiproliferative EGFR inhibitors and antimicrobial agents.
    Alzahrani AYA; Aboelez MO; Kamel MS; Selim HMRM; Alsaggaf AT; Hamd MAE; El-Remaily MAEAAA
    Mol Divers; 2024 Jun; ():. PubMed ID: 38851658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents.
    Kamboj P; Anjali ; Imtiyaz K; Rizvi MA; Nath V; Kumar V; Husain A; Amir M
    Sci Rep; 2024 Apr; 14(1):8457. PubMed ID: 38605072
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies.
    Othman IMM; Alamshany ZM; Tashkandi NY; Gad-Elkareem MAM; Anwar MM; Nossier ES
    Bioorg Chem; 2021 Sep; 114():105078. PubMed ID: 34161878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and in silico insights of novel 1,2,3-triazole benzenesulfonamide derivatives as potential carbonic anhydrase IX and XII inhibitors with promising anticancer activity.
    Abdelhakeem MM; Morcoss MM; Hanna DA; Lamie PF
    Bioorg Chem; 2024 Mar; 144():107154. PubMed ID: 38309003
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against resistant cancer cells, dual β-tubulin/c-Src inhibition, cell cycle arrest and apoptosis induction.
    Abdelall EKA; A H Elshemy H; Labib MB; E A Mohamed F
    Bioorg Chem; 2022 Mar; 120():105591. PubMed ID: 34998122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization.
    Ezelarab HAA; Ali TFS; Abbas SH; Sayed AM; Beshr EAM; Hassan HA
    Mol Divers; 2024 Apr; 28(2):563-580. PubMed ID: 36790582
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis, Molecular docking, and biological evaluation of novel 2,3-diaryl-1,3-thiazolidine-4-one derivatives as potential anti-inflammatory and cytotoxic agents.
    Mekhlef YO; AboulMagd AM; Gouda AM
    Bioorg Chem; 2023 Apr; 133():106411. PubMed ID: 36801792
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New pyranopyrazole based derivatives: Design, synthesis, and biological evaluation as potential topoisomerase II inhibitors, apoptotic inducers, and antiproliferative agents.
    Sobh EA; Kassab AE; El-Khouly EA; S A Hassan M
    Bioorg Chem; 2024 Mar; 144():107158. PubMed ID: 38301427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, Synthesis, and Biological Evaluation of 2-Mercaptobenzoxazole Derivatives as Potential Multi-Kinase Inhibitors.
    Alanazi MM; Aldawas S; Alsaif NA
    Pharmaceuticals (Basel); 2023 Jan; 16(1):. PubMed ID: 36678593
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel Mannich bases of ciprofloxacin with improved physicochemical properties, antibacterial, anticancer activities and caspase-3 mediated apoptosis.
    Abdel-Rahman IM; Mustafa M; Mohamed SA; Yahia R; Abdel-Aziz M; Abuo-Rahma GEA; Hayallah AM
    Bioorg Chem; 2021 Feb; 107():104629. PubMed ID: 33482607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of novel pyrazole derivatives as anti-inflammatory antimicrobial agents.
    Bekhit AA; Ashour HM; Bekhit Ael-D; Bekhit SA
    Med Chem; 2009 Mar; 5(2):103-17. PubMed ID: 19275709
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of new series of hexahydroquinoline and fused quinoline derivatives as potent inhibitors of wild-type EGFR and mutant EGFR (L858R and T790M).
    Shaheen MA; El-Emam AA; El-Gohary NS
    Bioorg Chem; 2020 Dec; 105():104274. PubMed ID: 33339080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New series of isoxazole derivatives targeting EGFR-TK: Synthesis, molecular modeling and antitumor evaluation.
    Warda ET; Shehata IA; El-Ashmawy MB; El-Gohary NS
    Bioorg Med Chem; 2020 Nov; 28(21):115674. PubMed ID: 33065442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New Benzimidazole-, 1,2,4-Triazole-, and 1,3,5-Triazine-Based Derivatives as Potential EGFR
    Hashem HE; Amr AEE; Nossier ES; Anwar MM; Azmy EM
    ACS Omega; 2022 Mar; 7(8):7155-7171. PubMed ID: 35252706
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers.
    El-Sharief AMS; Ammar YA; Belal A; El-Sharief MAMS; Mohamed YA; Mehany ABM; Elhag Ali GAM; Ragab A
    Bioorg Chem; 2019 Apr; 85():399-412. PubMed ID: 30665034
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and molecular modeling of quinoline-based derivatives as anti-breast cancer agents targeting EGFR/AKT signaling pathway.
    Batran RZ; El-Daly SM; El-Kashak WA; Ahmed EY
    Chem Biol Drug Des; 2022 Mar; 99(3):470-482. PubMed ID: 34939319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dual EGFR/VEGFR2 inhibitors and apoptosis inducers: Synthesis and antitumor activity of novel pyrazoline derivatives.
    Alkamaly OM; Altwaijry N; Sabour R; Harras MF
    Arch Pharm (Weinheim); 2021 Apr; 354(4):e2000351. PubMed ID: 33252142
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Microwave-assisted synthesis, spectroscopic characterization, and biological evaluation of fused thieno[2,3-d]pyrimidines as potential anti-cancer agents targeting EGFR
    Aboelez MO; Kamel MS; Belal A; El Badry Abdel-Aziz A; Abourehab MAS; Abdel-Ghany H; A El Hamd M; El-Remaily MAEAA
    Mol Divers; 2023 Apr; 27(2):901-917. PubMed ID: 35780205
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.