128 related articles for article (PubMed ID: 38858602)
1. K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.
Magits W; Steklov M; Jang H; Sewduth RN; Florentin A; Lechat B; Sheryazdanova A; Zhang M; Simicek M; Prag G; Nussinov R; Sablina A
EMBO J; 2024 Jun; ():. PubMed ID: 38858602
[TBL] [Abstract][Full Text] [Related]
2. Elevated FBXL6 activates both wild-type KRAS and mutant KRAS
Xiong HJ; Yu HQ; Zhang J; Fang L; Wu D; Lin XT; Xie CM
Mil Med Res; 2023 Dec; 10(1):68. PubMed ID: 38124228
[TBL] [Abstract][Full Text] [Related]
3. Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.
Hobbs GA; Gunawardena HP; Baker R; Campbell SL
Small GTPases; 2013; 4(3):186-92. PubMed ID: 24030601
[TBL] [Abstract][Full Text] [Related]
4. A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation.
Yin G; Kistler S; George SD; Kuhlmann N; Garvey L; Huynh M; Bagni RK; Lammers M; Der CJ; Campbell SL
J Biol Chem; 2017 Mar; 292(11):4446-4456. PubMed ID: 28154176
[TBL] [Abstract][Full Text] [Related]
5. RAS ubiquitylation modulates effector interactions.
Thurman R; Siraliev-Perez E; Campbell SL
Small GTPases; 2020 May; 11(3):180-185. PubMed ID: 29185849
[TBL] [Abstract][Full Text] [Related]
6. Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification.
Osaka N; Hirota Y; Ito D; Ikeda Y; Kamata R; Fujii Y; Chirasani VR; Campbell SL; Takeuchi K; Senda T; Sasaki AT
Front Mol Biosci; 2021; 8():707439. PubMed ID: 34307463
[TBL] [Abstract][Full Text] [Related]
7. Differential regulation of cellular activities by GTPase-activating protein and NF1.
al-Alawi N; Xu G; White R; Clark R; McCormick F; Feramisco JR
Mol Cell Biol; 1993 Apr; 13(4):2497-503. PubMed ID: 8455625
[TBL] [Abstract][Full Text] [Related]
8. Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype.
Yan N; Ricca C; Fletcher J; Glover T; Seizinger BR; Manne V
Cancer Res; 1995 Aug; 55(16):3569-75. PubMed ID: 7627966
[TBL] [Abstract][Full Text] [Related]
9. GAP positions catalytic H-Ras residue Q61 for GTP hydrolysis in molecular dynamics simulations, complicating chemical rescue of Ras deactivation.
Patel LA; Waybright TJ; Stephen AG; Neale C
Comput Biol Chem; 2023 Jun; 104():107835. PubMed ID: 36893567
[TBL] [Abstract][Full Text] [Related]
10. Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.
Sasaki AT; Carracedo A; Locasale JW; Anastasiou D; Takeuchi K; Kahoud ER; Haviv S; Asara JM; Pandolfi PP; Cantley LC
Sci Signal; 2011 Mar; 4(163):ra13. PubMed ID: 21386094
[TBL] [Abstract][Full Text] [Related]
11. Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation.
Sheffels E; Sealover NE; Wang C; Kim DH; Vazirani IA; Lee E; M Terrell E; Morrison DK; Luo J; Kortum RL
Sci Signal; 2018 Sep; 11(546):. PubMed ID: 30181243
[TBL] [Abstract][Full Text] [Related]
12. Lysines K117 and K147 play conserved roles in Ras activation from Drosophila to mammals.
Singh J; Karunaraj P; Luf M; Pfleger CM
G3 (Bethesda); 2023 Nov; 13(11):. PubMed ID: 37665961
[TBL] [Abstract][Full Text] [Related]
13. Measurement of KRAS-GTPase Activity.
Rabara D; Stephen AG
Methods Mol Biol; 2024; 2797():91-102. PubMed ID: 38570454
[TBL] [Abstract][Full Text] [Related]
14. Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function.
Clark GJ; Drugan JK; Terrell RS; Bradham C; Der CJ; Bell RM; Campbell S
Proc Natl Acad Sci U S A; 1996 Feb; 93(4):1577-81. PubMed ID: 8643674
[TBL] [Abstract][Full Text] [Related]
15. Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells.
Hiatt KK; Ingram DA; Zhang Y; Bollag G; Clapp DW
J Biol Chem; 2001 Mar; 276(10):7240-5. PubMed ID: 11080503
[TBL] [Abstract][Full Text] [Related]
16. An expanding role for RAS GTPase activating proteins (RAS GAPs) in cancer.
Maertens O; Cichowski K
Adv Biol Regul; 2014 May; 55():1-14. PubMed ID: 24814062
[TBL] [Abstract][Full Text] [Related]
17. RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers.
Nichols RJ; Haderk F; Stahlhut C; Schulze CJ; Hemmati G; Wildes D; Tzitzilonis C; Mordec K; Marquez A; Romero J; Hsieh T; Zaman A; Olivas V; McCoach C; Blakely CM; Wang Z; Kiss G; Koltun ES; Gill AL; Singh M; Goldsmith MA; Smith JAM; Bivona TG
Nat Cell Biol; 2018 Sep; 20(9):1064-1073. PubMed ID: 30104724
[TBL] [Abstract][Full Text] [Related]
18. The differential effects of the Gly-60 to Ala mutation on the interaction of H-Ras p21 with different downstream targets.
Hwang MC; Sung YJ; Hwang YW
J Biol Chem; 1996 Apr; 271(14):8196-202. PubMed ID: 8626511
[TBL] [Abstract][Full Text] [Related]
19. The GTPase-activating NF1 fragment of 91 amino acids reverses v-Ha-Ras-induced malignant phenotype.
Nur-E-Kamal MS; Varga M; Maruta H
J Biol Chem; 1993 Oct; 268(30):22331-7. PubMed ID: 8226742
[TBL] [Abstract][Full Text] [Related]
20. Characterization of Ras effector mutant interactions with the NF1-GAP related domain.
Marshall MS; Hettich LA
Oncogene; 1993 Feb; 8(2):425-31. PubMed ID: 8426748
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
