BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 38893537)

  • 1. The Discovery of Selective Protein Arginine Methyltransferase 5 Inhibitors in the Management of β-Thalassemia through Computational Methods.
    Pokharel B; Ravikumar Y; Rathinavel L; Chewonarin T; Pongpom M; Tipsuwan W; Koonyosying P; Srichairatanakool S
    Molecules; 2024 Jun; 29(11):. PubMed ID: 38893537
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In Silico Molecular Docking and Dynamics Simulation Analysis of Potential Histone Lysine Methyl Transferase Inhibitors for Managing β-Thalassemia.
    Ravikumar Y; Koonyosying P; Srichairatanakool S; Ponpandian LN; Kumaravelu J; Srichairatanakool S
    Molecules; 2023 Oct; 28(21):. PubMed ID: 37959685
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors.
    Zhu K; Song JL; Tao HR; Cheng ZQ; Jiang CS; Zhang H
    Bioorg Med Chem Lett; 2018 Dec; 28(23-24):3693-3699. PubMed ID: 30366617
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.
    Ye Y; Zhang B; Mao R; Zhang C; Wang Y; Xing J; Liu YC; Luo X; Ding H; Yang Y; Zhou B; Jiang H; Chen K; Luo C; Zheng M
    Org Biomol Chem; 2017 May; 15(17):3648-3661. PubMed ID: 28397890
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations.
    Zhang Q; Zhang L; Jin J; Fan Y; Wang X; Hu H; Ye X; Wang L; Cao C; Ye F
    J Mol Model; 2022 Jun; 28(7):184. PubMed ID: 35680707
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations.
    Tao H; Yan X; Zhu K; Zhang H
    Chem Pharm Bull (Tokyo); 2019; 67(4):382-388. PubMed ID: 30930442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations.
    Zhu K; Jiang C; Tao H; Liu J; Zhang H; Luo C
    Bioorg Med Chem Lett; 2018 May; 28(9):1476-1483. PubMed ID: 29628326
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods.
    Zhu K; Jiang CS; Hu J; Liu X; Yan X; Tao H; Luo C; Zhang H
    Biochem Biophys Res Commun; 2018 Jan; 495(1):721-727. PubMed ID: 29154828
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and Activity of Triazole-Adenosine Analogs as Protein Arginine Methyltransferase 5 Inhibitors.
    Brown T; Cao M; Zheng YG
    Molecules; 2022 Jun; 27(12):. PubMed ID: 35744905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Development of Tetrazole Derivatives as Protein Arginine Methyltransferase I (PRMT I) Inhibitors.
    Sun Y; Wang Z; Yang H; Zhu X; Wu H; Ma L; Xu F; Hong W; Wang H
    Int J Mol Sci; 2019 Aug; 20(15):. PubMed ID: 31390828
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays.
    Ye F; Zhang W; Ye X; Jin J; Lv Z; Luo C
    J Chem Inf Model; 2018 May; 58(5):1066-1073. PubMed ID: 29672052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arginine Methyltransferase 5 (PRMT5) Inhibitors with 3-(1H-benzo[d]imidazol- 2-yl)anilines Core Identified by Virtual Screening and Biological Evaluation.
    Zhang Y; Zhu K; Zhang J; Zhang JH; Song Z; Zhang X; Liu SK; Jiang CS
    Curr Pharm Des; 2023; 29(6):474-479. PubMed ID: 36790004
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations.
    Zhu K; Tao H; Song JL; Jin L; Zhang Y; Liu J; Chen Z; Jiang CS; Luo C; Zhang H
    Bioorg Chem; 2018 Dec; 81():289-298. PubMed ID: 30172110
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations.
    Ji S; Ma S; Wang WJ; Huang SZ; Wang TQ; Xiang R; Hu YG; Chen Q; Li LL; Yang SY
    Chem Biol Drug Des; 2017 Apr; 89(4):585-598. PubMed ID: 27714957
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization.
    Mao R; Shao J; Zhu K; Zhang Y; Ding H; Zhang C; Shi Z; Jiang H; Sun D; Duan W; Luo C
    J Med Chem; 2017 Jul; 60(14):6289-6304. PubMed ID: 28650658
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein Arginine Methyltransferase 5 (PRMT5) as an Anticancer Target and Its Inhibitor Discovery.
    Wang Y; Hu W; Yuan Y
    J Med Chem; 2018 Nov; 61(21):9429-9441. PubMed ID: 29870258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigating the binding preferences of small molecule inhibitors of human protein arginine methyltransferase 1 using molecular modelling.
    Hong W; Li J; Laughton CA; Yap LF; Paterson IC; Wang H
    J Mol Graph Model; 2014 Jun; 51():193-202. PubMed ID: 24937176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In silico analysis of marine natural product for protein arginine methyltransferase 5(PRMT5) inhibitors based on pharmacophore and molecular docking.
    Luo L; Tan H; Liao Y
    J Biomol Struct Dyn; 2023; 41(22):13180-13197. PubMed ID: 36856049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Flavokawain A is a natural inhibitor of PRMT5 in bladder cancer.
    Liu S; Liu Z; Piao C; Zhang Z; Kong C; Yin L; Liu X
    J Exp Clin Cancer Res; 2022 Oct; 41(1):293. PubMed ID: 36199122
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico investigations on the binding efficacy and allosteric mechanism of six different natural product compounds towards PTP1B inhibition through docking and molecular dynamics simulations.
    SarathKumar B; Lakshmi BS
    J Mol Model; 2019 Aug; 25(9):272. PubMed ID: 31451955
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.