133 related articles for article (PubMed ID: 38902949)
1. A computational framework to in silico screen for drug-induced hepatocellular toxicity.
Zhao Y; Park JY; Yang D; Zhang M
Toxicol Sci; 2024 Jun; ():. PubMed ID: 38902949
[TBL] [Abstract][Full Text] [Related]
2. Improved Detection of Drug-Induced Liver Injury by Integrating Predicted
Seal S; Williams DP; Hosseini-Gerami L; Mahale M; Carpenter AE; Spjuth O; Bender A
bioRxiv; 2024 Jun; ():. PubMed ID: 38895462
[TBL] [Abstract][Full Text] [Related]
3. Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Kang W; Podtelezhnikov AA; Tanis KQ; Pacchione S; Su M; Bleicher KB; Wang Z; Laws GM; Griffiths TG; Kuhls MC; Chen Q; Knemeyer I; Marsh DJ; Mitra K; Lebron J; Sistare FD
Toxicol Sci; 2020 Sep; 177(1):121-139. PubMed ID: 32559289
[TBL] [Abstract][Full Text] [Related]
4. Toxicogenomics of drug induced liver injury - from mechanistic understanding to early prediction.
Lauschke VM
Drug Metab Rev; 2021 May; 53(2):245-252. PubMed ID: 33683927
[TBL] [Abstract][Full Text] [Related]
5. Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
Laifenfeld D; Qiu L; Swiss R; Park J; Macoritto M; Will Y; Younis HS; Lawton M
Toxicol Sci; 2014 Jan; 137(1):234-48. PubMed ID: 24136188
[TBL] [Abstract][Full Text] [Related]
6. Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.
Fredriksson L; Wink S; Herpers B; Benedetti G; Hadi M; de Bont H; Groothuis G; Luijten M; Danen E; de Graauw M; Meerman J; van de Water B
Toxicol Sci; 2014 Jul; 140(1):144-59. PubMed ID: 24752500
[TBL] [Abstract][Full Text] [Related]
7. Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury
Rana P; Aleo MD; Wen X; Kogut S
Acta Pharm Sin B; 2021 Dec; 11(12):3857-3868. PubMed ID: 35024312
[TBL] [Abstract][Full Text] [Related]
8. Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure.
Liu A; Walter M; Wright P; Bartosik A; Dolciami D; Elbasir A; Yang H; Bender A
Biol Direct; 2021 Jan; 16(1):6. PubMed ID: 33461600
[TBL] [Abstract][Full Text] [Related]
9. High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids.
Shinozawa T; Kimura M; Cai Y; Saiki N; Yoneyama Y; Ouchi R; Koike H; Maezawa M; Zhang RR; Dunn A; Ferguson A; Togo S; Lewis K; Thompson WL; Asai A; Takebe T
Gastroenterology; 2021 Feb; 160(3):831-846.e10. PubMed ID: 33039464
[TBL] [Abstract][Full Text] [Related]
10. Prediction models for drug-induced hepatotoxicity by using weighted molecular fingerprints.
Kim E; Nam H
BMC Bioinformatics; 2017 May; 18(Suppl 7):227. PubMed ID: 28617228
[TBL] [Abstract][Full Text] [Related]
11. Mechanism-based integrated assay systems for the prediction of drug-induced liver injury.
Kawaguchi M; Nukaga T; Sekine S; Takemura A; Susukida T; Oeda S; Kodama A; Hirota M; Kouzuki H; Ito K
Toxicol Appl Pharmacol; 2020 May; 394():114958. PubMed ID: 32198022
[TBL] [Abstract][Full Text] [Related]
12. Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis.
Iorga A; Dara L; Kaplowitz N
Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28486401
[TBL] [Abstract][Full Text] [Related]
13. Human-relevant mechanisms and risk factors for TAK-875-Induced liver injury identified via a gene pathway-based approach in Collaborative Cross mice.
Mosedale M; Cai Y; Eaddy JS; Kirby PJ; Wolenski FS; Dragan Y; Valdar W
Toxicology; 2021 Sep; 461():152902. PubMed ID: 34418498
[TBL] [Abstract][Full Text] [Related]
14. CYP7A1 Gene Induction via SHP-Dependent or Independent Mechanisms can Increase the Risk of Drug-Induced Liver Injury Independently or in Synergy with BSEP Inhibition.
Niu C; Xie X; Liu R; Liang X; Hu Y; Lai Y
Drug Metab Dispos; 2024 Apr; 52(5):432-441. PubMed ID: 38485279
[TBL] [Abstract][Full Text] [Related]
15. Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.
Williams DP; Lazic SE; Foster AJ; Semenova E; Morgan P
Chem Res Toxicol; 2020 Jan; 33(1):239-248. PubMed ID: 31535850
[TBL] [Abstract][Full Text] [Related]
16. An Update on Drug-induced Liver Injury.
Devarbhavi H
J Clin Exp Hepatol; 2012 Sep; 2(3):247-59. PubMed ID: 25755441
[TBL] [Abstract][Full Text] [Related]
17. In Silico Identification of Proteins Associated with Drug-induced Liver Injury Based on the Prediction of Drug-target Interactions.
Ivanov S; Semin M; Lagunin A; Filimonov D; Poroikov V
Mol Inform; 2017 Jul; 36(7):. PubMed ID: 28145637
[TBL] [Abstract][Full Text] [Related]
18. Deep Learning on High-Throughput Transcriptomics to Predict Drug-Induced Liver Injury.
Li T; Tong W; Roberts R; Liu Z; Thakkar S
Front Bioeng Biotechnol; 2020; 8():562677. PubMed ID: 33330410
[TBL] [Abstract][Full Text] [Related]
19. Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury.
Wink S; Hiemstra SW; Huppelschoten S; Klip JE; van de Water B
Arch Toxicol; 2018 May; 92(5):1797-1814. PubMed ID: 29502165
[TBL] [Abstract][Full Text] [Related]
20. Applications of In Silico Models to Predict Drug-Induced Liver Injury.
Lin J; Li M; Mak W; Shi Y; Zhu X; Tang Z; He Q; Xiang X
Toxics; 2022 Dec; 10(12):. PubMed ID: 36548621
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]