125 related articles for article (PubMed ID: 38903945)
1. Cytotoxicity of phosphoramidate, bis-amidate and cycloSal prodrug metabolites against tumour and normal cells.
Farrell RE; Steele H; Middleton RJ; Skropeta D; Liu GJ
RSC Med Chem; 2024 Jun; 15(6):1973-1981. PubMed ID: 38903945
[TBL] [Abstract][Full Text] [Related]
2. Efficiency of bis-amidate phosphonate prodrugs.
Lentini NA; Huang X; Schladetsch MA; Hsiao CC; Wiemer DF; Wiemer AJ
Bioorg Med Chem Lett; 2022 Jun; 66():128724. PubMed ID: 35405283
[TBL] [Abstract][Full Text] [Related]
3. Comparative Pharmacology of a Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor of Enolase after Oral and Parenteral Administration.
Yan VC; Barekatain Y; Lin YH; Satani N; Hammoudi N; Arthur K; Georgiou DK; Jiang Y; Sun Y; Marszalek JR; Millward SW; Muller FL
ACS Pharmacol Transl Sci; 2023 Feb; 6(2):245-252. PubMed ID: 36798479
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver.
Erion MD; Reddy KR; Boyer SH; Matelich MC; Gomez-Galeno J; Lemus RH; Ugarkar BG; Colby TJ; Schanzer J; Van Poelje PD
J Am Chem Soc; 2004 Apr; 126(16):5154-63. PubMed ID: 15099098
[TBL] [Abstract][Full Text] [Related]
5. Drug repurposing: phosphate prodrugs of anticancer and antiviral FDA-approved nucleosides as novel antimicrobials.
Pertusati F; Pileggi E; Richards J; Wootton M; Van Leemputte T; Persoons L; De Coster D; Villanueva X; Daelemans D; Steenackers H; McGuigan C; Serpi M
J Antimicrob Chemother; 2020 Oct; 75(10):2864-2878. PubMed ID: 32688391
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and Evaluation of Prodrugs of α-Carboxy Nucleoside Phosphonates.
Ford A; Mullins ND; Balzarini J; Maguire AR
J Org Chem; 2022 Nov; 87(21):14793-14808. PubMed ID: 36283025
[TBL] [Abstract][Full Text] [Related]
7. Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis.
Šmídková M; Dvoráková A; Tloust'ová E; Česnek M; Janeba Z; Mertlíková-Kaiserová H
Antimicrob Agents Chemother; 2014; 58(2):664-71. PubMed ID: 24145524
[TBL] [Abstract][Full Text] [Related]
8. Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).
Balzarini J; Naesens L; Aquaro S; Knispel T; Perno C; De Clercq E; Meier C
Mol Pharmacol; 1999 Dec; 56(6):1354-61. PubMed ID: 10570065
[TBL] [Abstract][Full Text] [Related]
9. Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of
Yan VC; Pham CD; Ballato ES; Yang KL; Arthur K; Khadka S; Barekatain Y; Shrestha P; Tran T; Poral AH; Washington M; Raghavan S; Czako B; Pisaneschi F; Lin YH; Satani N; Hammoudi N; Ackroyd JJ; Georgiou DK; Millward SW; Muller FL
J Med Chem; 2022 Oct; 65(20):13813-13832. PubMed ID: 36251833
[TBL] [Abstract][Full Text] [Related]
10. Antiviral activity of cyclosaligenyl prodrugs of acyclovir, carbovir and abacavir.
Balzarini J; Haller-Meier F; De Clercq E; Meier C
Antivir Chem Chemother; 2001 Sep; 12(5):301-6. PubMed ID: 11900349
[TBL] [Abstract][Full Text] [Related]
11. A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities.
Jansa P; Baszczyňski O; Dračínský M; Votruba I; Zídek Z; Bahador G; Stepan G; Cihlar T; Mackman R; Holý A; Janeba Z
Eur J Med Chem; 2011 Sep; 46(9):3748-54. PubMed ID: 21664011
[TBL] [Abstract][Full Text] [Related]
12. Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity.
Frydrych J; Keough DT; Chavchich M; Travis J; Dračínský M; Edstein MD; Guddat LW; Hocková D; Janeba Z
Eur J Med Chem; 2021 Jul; 219():113416. PubMed ID: 33887682
[TBL] [Abstract][Full Text] [Related]
13. Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer.
Tokay E; Güngör T; Hacıoğlu N; Önder FC; Gülhan ÜG; Tok TT; Çelik A; Ay M; Köçkar F
Eur J Med Chem; 2020 Feb; 187():111937. PubMed ID: 31841727
[TBL] [Abstract][Full Text] [Related]
14. Evaluating the abilities of diverse nitroaromatic prodrug metabolites to exit a model Gram negative vector for bacterial-directed enzyme-prodrug therapy.
Chan-Hyams JVE; Copp JN; Smaill JB; Patterson AV; Ackerley DF
Biochem Pharmacol; 2018 Dec; 158():192-200. PubMed ID: 30352235
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug.
Tobias SC; Borch RF
Mol Pharm; 2004; 1(2):112-6. PubMed ID: 15832507
[TBL] [Abstract][Full Text] [Related]
16. cycloSal-PMEA and cycloAmb-PMEA: potentially new phosphonate prodrugs based on the cycloSal-pronucleotide approach.
Meier C; Görbig U; Müller C; Balzarini J
J Med Chem; 2005 Dec; 48(25):8079-86. PubMed ID: 16335932
[TBL] [Abstract][Full Text] [Related]
17. Evaluation of the anti-cervical cancer effect of a prodrug :CBZ-AAN-DOX with hypoxic cell culture and tumor-bearing zebrafish models.
Chen HC; Rui W; You SY; Liu XW; Huang J; Chen HY
Exp Cell Res; 2020 Jun; 391(1):111980. PubMed ID: 32229193
[TBL] [Abstract][Full Text] [Related]
18. Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).
Parang K; Wiebe LI; Knaus EE
Curr Med Chem; 2000 Oct; 7(10):995-1039. PubMed ID: 10911016
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological studies of novel nucleoside phosphoramidate prodrugs.
Tobias SC; Borch RF
J Med Chem; 2001 Dec; 44(25):4475-80. PubMed ID: 11728193
[TBL] [Abstract][Full Text] [Related]
20. Comparison of the disposition of ester prodrugs of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine [PMEA] in Caco-2 monolayers.
Annaert P; Gosselin G; Pompon A; Benzaria S; Valette G; Imbach JL; Naesens L; Hatse S; de Clercq E; Van den Mooter G; Kinget R; Augustijns P
Pharm Res; 1998 Feb; 15(2):239-45. PubMed ID: 9523310
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]