119 related articles for article (PubMed ID: 38908237)
1. Development and validation of bioanalytical assays for the quantification of 9MW2821, a nectin-4-targeting antibody-drug conjugate.
Fang P; You M; Cao Y; Feng Q; Shi L; Wang J; Sun X; Yu D; Zhou W; Yin L; Mei F; Zhu X; Cheng A; Tan X
J Pharm Biomed Anal; 2024 Jun; 248():116318. PubMed ID: 38908237
[TBL] [Abstract][Full Text] [Related]
2. Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers.
Zhou W; Fang P; Yu D; Ren H; You M; Yin L; Mei F; Zhu H; Wang Z; Xu H; Cao Y; Sun X; Xu X; Bi J; Wang J; Ma L; Wang X; Chen L; Zhang Y; Cen X; Zhu X; Lou L; Liu D; Tan X; Yang J; Meng T; Shen J
Mol Cancer Ther; 2023 Aug; 22(8):913-925. PubMed ID: 37196158
[TBL] [Abstract][Full Text] [Related]
3. Determination of drug-to-antibody ratio of antibody-drug conjugate in biological samples using microflow-liquid chromatography/high-resolution mass spectrometry.
Inoue K; Mochizuki T; Kasamori N; Komori T
Bioanalysis; 2022 Dec; 14(24):1533-1545. PubMed ID: 36825963
[TBL] [Abstract][Full Text] [Related]
4. Multiplex LC-MS/MS Assays for Clinical Bioanalysis of MEDI4276, an Antibody-Drug Conjugate of Tubulysin Analogue Attached via Cleavable Linker to a Biparatopic Humanized Antibody against HER-2.
Faria M; Peay M; Lam B; Ma E; Yuan M; Waldron M; Mylott WR; Liang M; Rosenbaum AI
Antibodies (Basel); 2019 Jan; 8(1):. PubMed ID: 31544817
[TBL] [Abstract][Full Text] [Related]
5. Development and validation of bioanalytical methods to support clinical study of disitamab vedotin.
Wu B; Li Q; Wang L; Chen F; Jiang J
Bioanalysis; 2024; 16(9):385-400. PubMed ID: 38530234
[TBL] [Abstract][Full Text] [Related]
6. A single liquid chromatography-quadrupole time-of-flight mass spectrometric method for the quantification of total antibody, antibody-conjugated drug and free payload of antibody-drug conjugates.
Byeon JJ; Park MH; Shin SH; Lee BI; Park Y; Choi J; Kim N; Kang Y; Shin YG
Biomed Chromatogr; 2018 Jul; 32(7):e4229. PubMed ID: 29505175
[TBL] [Abstract][Full Text] [Related]
7. Where Did the Linker-Payload Go? A Quantitative Investigation on the Destination of the Released Linker-Payload from an Antibody-Drug Conjugate with a Maleimide Linker in Plasma.
Wei C; Zhang G; Clark T; Barletta F; Tumey LN; Rago B; Hansel S; Han X
Anal Chem; 2016 May; 88(9):4979-86. PubMed ID: 27075639
[TBL] [Abstract][Full Text] [Related]
8. Calculated conjugated payload from immunoassay and LC-MS intact protein analysis measurements of antibody-drug conjugate.
Rago B; Clark T; King L; Zhang J; Tumey LN; Li F; Barletta F; Wei C; Leal M; Hansel S; Han X
Bioanalysis; 2016 Nov; 8(21):2205-2217. PubMed ID: 27682846
[TBL] [Abstract][Full Text] [Related]
9. Bioanalysis of the Bicycle
Tweed JA; Adams-Dam F; Allanson J; Holmes K; Senior R; Xu H; Li M; Bennett G; Jeffrey P
Bioanalysis; 2024 Feb; 16(3):155-169. PubMed ID: 38088822
[No Abstract] [Full Text] [Related]
10. Detection of antibody-conjugate payload in cynomolgus monkey serum by a high throughput capture LC-MS/MS bioanalysis method.
Wang S; Wang F; Wang L; Liu Z; Liu M; Li S; Wang Y; Sun X; Jiang J
J Pharm Biomed Anal; 2023 Apr; 227():115069. PubMed ID: 36854219
[TBL] [Abstract][Full Text] [Related]
11. A Two-Step Immunocapture LC/MS/MS Assay for Plasma Stability and Payload Migration Assessment of Cysteine-Maleimide-Based Antibody Drug Conjugates.
Dong L; Li C; Locuson C; Chen S; Qian MG
Anal Chem; 2018 May; 90(10):5989-5994. PubMed ID: 29688004
[TBL] [Abstract][Full Text] [Related]
12. An Innovative Site-Specific Anti-HER2 Antibody-Drug Conjugate with High Homogeneity and Improved Therapeutic Index.
Hui X; Yuan C; Cao W; Ge W; Zhang D; Dan M; Zhao Q; Liu B; Yao B
Onco Targets Ther; 2022; 15():331-343. PubMed ID: 35422630
[TBL] [Abstract][Full Text] [Related]
13. A generic approach for simultaneous measurements of total antibody and cleavable antibody-conjugated drug by LC/MS/MS.
Xu L; Packer LE; Li C; Abdul-Hadi K; Veiby P
Anal Biochem; 2017 Nov; 537():33-36. PubMed ID: 28867503
[TBL] [Abstract][Full Text] [Related]
14. Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC-MS/MS approach: Assay development, validation, and a case study.
Liu A; Kozhich A; Passmore D; Gu H; Wong R; Zambito F; Rangan VS; Myler H; Aubry AF; Arnold ME; Wang J
J Chromatogr B Analyt Technol Biomed Life Sci; 2015 Oct; 1002():54-62. PubMed ID: 26310897
[TBL] [Abstract][Full Text] [Related]
15. Method development of a novel PK assay for antibody-conjugated drug measurement of ADCs using peptide-linker drug analyte.
Hyung SJ; Li D; Koppada N; Kaur S; Saad OM
Anal Bioanal Chem; 2019 May; 411(12):2587-2596. PubMed ID: 30828756
[TBL] [Abstract][Full Text] [Related]
16. Enzyme-linked immunosorbent assays for quantification of MMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera.
Pei M; Liu T; Ouyang L; Sun J; Deng X; Sun X; Wu W; Huang P; Chen YL; Tan X; Liu X; Zhu P; Liu Y; Wang D; Wu J; Wang Q; Wang G; Gong L; Qin Q; Wang C
J Pharm Anal; 2022 Aug; 12(4):645-652. PubMed ID: 36105165
[TBL] [Abstract][Full Text] [Related]
17. Therapeutic efficacy, pharmacokinetic profiles, and toxicological activities of humanized antibody-drug conjugate Zt/g4-MMAE targeting RON receptor tyrosine kinase for cancer therapy.
Yao HP; Feng L; Suthe SR; Chen LH; Weng TH; Hu CY; Jun ES; Wu ZG; Wang WL; Kim SC; Tong XM; Wang MH
J Immunother Cancer; 2019 Mar; 7(1):75. PubMed ID: 30871619
[TBL] [Abstract][Full Text] [Related]
18. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate.
Sanderson RJ; Hering MA; James SF; Sun MM; Doronina SO; Siadak AW; Senter PD; Wahl AF
Clin Cancer Res; 2005 Jan; 11(2 Pt 1):843-52. PubMed ID: 15701875
[TBL] [Abstract][Full Text] [Related]
19. Development and Properties of Valine-Alanine based Antibody-Drug Conjugates with Monomethyl Auristatin E as the Potent Payload.
Wang Y; Fan S; Zhong W; Zhou X; Li S
Int J Mol Sci; 2017 Aug; 18(9):. PubMed ID: 28841157
[TBL] [Abstract][Full Text] [Related]
20. Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody-Drug Conjugates.
Caculitan NG; Dela Cruz Chuh J; Ma Y; Zhang D; Kozak KR; Liu Y; Pillow TH; Sadowsky J; Cheung TK; Phung Q; Haley B; Lee BC; Akita RW; Sliwkowski MX; Polson AG
Cancer Res; 2017 Dec; 77(24):7027-7037. PubMed ID: 29046337
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]