136 related articles for article (PubMed ID: 38912292)
1. APOE4 dysregulates autophagy in cultured cells.
Fote GM; Steffan JS
Autophagy Rep; 2022; 1(1):29-33. PubMed ID: 38912292
[TBL] [Abstract][Full Text] [Related]
2. Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins.
Fote GM; Geller NR; Efstathiou NE; Hendricks N; Vavvas DG; Reidling JC; Thompson LM; Steffan JS
J Cell Sci; 2022 Jan; 135(2):. PubMed ID: 34982109
[TBL] [Abstract][Full Text] [Related]
3. The Interplay Between Apolipoprotein E4 and the Autophagic-Endocytic-Lysosomal Axis.
Schmukler E; Michaelson DM; Pinkas-Kramarski R
Mol Neurobiol; 2018 Aug; 55(8):6863-6880. PubMed ID: 29353455
[TBL] [Abstract][Full Text] [Related]
4. The Contributions of the Endolysosomal Compartment and Autophagy to APOEɛ4 Allele-Mediated Increase in Alzheimer's Disease Risk.
Asiamah EA; Feng B; Guo R; Yaxing X; Du X; Liu X; Zhang J; Cui H; Ma J
J Alzheimers Dis; 2024; 97(3):1007-1031. PubMed ID: 38306054
[TBL] [Abstract][Full Text] [Related]
5. Impaired Autophagy in APOE4 Astrocytes.
Simonovitch S; Schmukler E; Bespalko A; Iram T; Frenkel D; Holtzman DM; Masliah E; Michaelson DM; Pinkas-Kramarski R
J Alzheimers Dis; 2016; 51(3):915-27. PubMed ID: 26923027
[TBL] [Abstract][Full Text] [Related]
6. ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes.
Rawat V; Wang S; Sima J; Bar R; Liraz O; Gundimeda U; Parekh T; Chan J; Johansson JO; Tang C; Chui HC; Harrington MG; Michaelson DM; Yassine HN
J Neurosci; 2019 Nov; 39(48):9611-9622. PubMed ID: 31641056
[TBL] [Abstract][Full Text] [Related]
7. Roles of ApoE4 on the Pathogenesis in Alzheimer's Disease and the Potential Therapeutic Approaches.
Sun YY; Wang Z; Huang HC
Cell Mol Neurobiol; 2023 Oct; 43(7):3115-3136. PubMed ID: 37227619
[TBL] [Abstract][Full Text] [Related]
8. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
Aleshkov S; Abraham CR; Zannis VI
Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
[TBL] [Abstract][Full Text] [Related]
9. Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs.
Parcon PA; Balasubramaniam M; Ayyadevara S; Jones RA; Liu L; Shmookler Reis RJ; Barger SW; Mrak RE; Griffin WST
Alzheimers Dement; 2018 Feb; 14(2):230-242. PubMed ID: 28945989
[TBL] [Abstract][Full Text] [Related]
10. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
[TBL] [Abstract][Full Text] [Related]
11. Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models.
Huang Y
Biochem Soc Trans; 2011 Aug; 39(4):924-32. PubMed ID: 21787325
[TBL] [Abstract][Full Text] [Related]
12. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
13. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
[TBL] [Abstract][Full Text] [Related]
14. Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer's disease by targeted small molecules.
Balasubramaniam M; Narasimhappagari J; Liu L; Ganne A; Ayyadevara S; Atluri R; Ayyadevara H; Caldwell G; Reis RJS; Barger SW; Griffin WST
Commun Biol; 2024 Jan; 7(1):60. PubMed ID: 38191671
[TBL] [Abstract][Full Text] [Related]
15. Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice.
Larramona-Arcas R; González-Arias C; Perea G; Gutiérrez A; Vitorica J; García-Barrera T; Gómez-Ariza JL; Pascua-Maestro R; Ganfornina MD; Kara E; Hudry E; Martinez-Vicente M; Vila M; Galea E; Masgrau R
Mol Neurodegener; 2020 Jun; 15(1):35. PubMed ID: 32517777
[TBL] [Abstract][Full Text] [Related]
16. Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits.
Belinson H; Lev D; Masliah E; Michaelson DM
J Neurosci; 2008 Apr; 28(18):4690-701. PubMed ID: 18448646
[TBL] [Abstract][Full Text] [Related]
17. APOE and Alzheimer's Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer's Pathogenesis.
Uddin MS; Kabir MT; Al Mamun A; Abdel-Daim MM; Barreto GE; Ashraf GM
Mol Neurobiol; 2019 Apr; 56(4):2450-2465. PubMed ID: 30032423
[TBL] [Abstract][Full Text] [Related]
18. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
[TBL] [Abstract][Full Text] [Related]
19. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
[TBL] [Abstract][Full Text] [Related]
20. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]