These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 38925015)

  • 1. Multimechanism biological profiling of tetrahydro-β-carboline analogues as selective HDAC6 inhibitors for the treatment of Alzheimer's disease.
    Liang T; Liu S; Dang B; Luan X; Guo Y; Steimbach RR; Hu J; Lu L; Yue P; Wang R; Zheng M; Gao J; Yin X; Chen X
    Eur J Med Chem; 2024 Sep; 275():116624. PubMed ID: 38925015
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease.
    Wang XX; Xie F; Jia CC; Yan N; Zeng YL; Wu JD; Liu ZP
    Eur J Med Chem; 2021 Dec; 225():113821. PubMed ID: 34517222
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.
    Leonhardt M; Sellmer A; Krämer OH; Dove S; Elz S; Kraus B; Beyer M; Mahboobi S
    Eur J Med Chem; 2018 May; 152():329-357. PubMed ID: 29738953
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010-2020).
    Li Y; Sang S; Ren W; Pei Y; Bian Y; Chen Y; Sun H
    Eur J Med Chem; 2021 Dec; 226():113874. PubMed ID: 34619465
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability.
    Scheuerer S; Motlova L; Schäker-Hübner L; Sellmer A; Feller F; Ertl FJ; Koch P; Hansen FK; Barinka C; Mahboobi S
    Eur J Med Chem; 2024 Oct; 276():116676. PubMed ID: 39067437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of brain penetrant benzazepine-based histone deacetylase 6 inhibitors for alleviating stroke-induced brain infarction.
    Guo Z; Zhang Z; Zhang Y; Wang G; Huang Z; Zhang Q; Li J
    Eur J Med Chem; 2021 Jun; 218():113383. PubMed ID: 33799069
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological activity of oxyevodiamine-based histone deacetylase 6 inhibitors.
    Li SY; Guo JS; Yang YJ
    J Asian Nat Prod Res; 2024 Nov; 26(11):1328-1338. PubMed ID: 38945152
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Re-exploration of tetrahydro-β-carboline scaffold: Discovery of selective histone deacetylase 6 inhibitors with neurite outgrowth-promoting and neuroprotective activities.
    Wen W; Hu J; Wang C; Yang R; Zhang Y; Huang B; Qiao T; Wang J; Chen X
    Bioorg Med Chem Lett; 2024 Apr; 102():129670. PubMed ID: 38387692
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enantioselective synthesis and biological investigation of tetrahydro-β-carboline-based HDAC6 inhibitors with improved solubility.
    Grünstein E; Sellmer A; Mahboobi S
    Arch Pharm (Weinheim); 2019 Jun; 352(6):e1900026. PubMed ID: 31056792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes.
    Lee HY; Fan SJ; Huang FI; Chao HY; Hsu KC; Lin TE; Yeh TK; Lai MJ; Li YH; Huang HL; Yang CR; Liou JP
    J Med Chem; 2018 Aug; 61(16):7087-7102. PubMed ID: 30028616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and neuroprotective biological evaluation of novel HDAC6 inhibitors incorporating benzothiadiazinyl systems as cap groups.
    Han B; Gu X; Wang M; Wang H; Sun N; Yang X; Zhang Q
    Chem Biol Drug Des; 2024 May; 103(5):e14556. PubMed ID: 38772881
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease.
    Rabal O; Sánchez-Arias JA; Cuadrado-Tejedor M; de Miguel I; Pérez-González M; García-Barroso C; Ugarte A; Estella-Hermoso de Mendoza A; Sáez E; Espelosin M; Ursua S; Haizhong T; Wei W; Musheng X; Garcia-Osta A; Oyarzabal J
    Eur J Med Chem; 2018 Apr; 150():506-524. PubMed ID: 29549837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma.
    Kassab SE; Mowafy S; Alserw AM; Seliem JA; El-Naggar SM; Omar NN; Awad MM
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1062-1077. PubMed ID: 31072216
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of dual-function inhibitors targeting NMDAR and HDAC for Alzheimer's disease.
    He F; Ran Y; Li X; Wang D; Zhang Q; Lv J; Yu C; Qu Y; Zhang X; Xu A; Wei C; Chou CJ; Wu J
    Bioorg Chem; 2020 Oct; 103():104109. PubMed ID: 32768741
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects
    He F; Chou CJ; Scheiner M; Poeta E; Yuan Chen N; Gunesch S; Hoffmann M; Sotriffer C; Monti B; Maurice T; Decker M
    J Med Chem; 2021 Apr; 64(7):3794-3812. PubMed ID: 33769811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer's disease.
    Liao Q; Li Q; Zhao Y; Jiang P; Yan Y; Sun H; Liu W; Feng F; Qu W
    Bioorg Chem; 2020 Jun; 99():103844. PubMed ID: 32325336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivatives as HDAC6 selective inhibitors.
    Liang T; Xue J; Yao Z; Ye Y; Yang X; Hou X; Fang H
    Eur J Med Chem; 2021 Oct; 221():113526. PubMed ID: 33992929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and evaluation of novel bivalent β-carboline derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Zhao Y; Ye F; Xu J; Liao Q; Chen L; Zhang W; Sun H; Liu W; Feng F; Qu W
    Bioorg Med Chem; 2018 Jul; 26(13):3812-3824. PubMed ID: 29960728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
    Vögerl K; Ong N; Senger J; Herp D; Schmidtkunz K; Marek M; Müller M; Bartel K; Shaik TB; Porter NJ; Robaa D; Christianson DW; Romier C; Sippl W; Jung M; Bracher F
    J Med Chem; 2019 Feb; 62(3):1138-1166. PubMed ID: 30645113
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors to suppress tumor metastasis and invasion in vitro and in vivo.
    Li Y; Quan J; Song H; Li D; Ma E; Wang Y; Ma C
    Bioorg Chem; 2021 Sep; 114():105081. PubMed ID: 34153811
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.