These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Seeger T; Shrestha R; Lam CK; Chen C; McKeithan WL; Lau E; Wnorowski A; McMullen G; Greenhaw M; Lee J; Oikonomopoulos A; Lee S; Yang H; Mercola M; Wheeler M; Ashley EA; Yang F; Karakikes I; Wu JC Circulation; 2019 Feb; 139(6):799-811. PubMed ID: 30586709 [TBL] [Abstract][Full Text] [Related]
4. Enhanced myofilament calcium sensitivity aggravates abnormal calcium handling and diastolic dysfunction in patient-specific induced pluripotent stem cell-derived cardiomyocytes with MYH7 mutation. Guo G; Wang L; Li X; Fu W; Cao J; Zhang J; Liu Y; Liu M; Wang M; Zhao G; Zhao X; Zhou Y; Niu S; Liu G; Zhang Y; Dong J; Tao H; Zhao X Cell Calcium; 2024 Jan; 117():102822. PubMed ID: 38101154 [TBL] [Abstract][Full Text] [Related]
6. Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with MYL2-R58Q-Mediated Apical Hypertrophic Cardiomyopathy Show Hypertrophy, Myofibrillar Disarray, and Calcium Perturbations. Zhou W; Bos JM; Ye D; Tester DJ; Hrstka S; Maleszewski JJ; Ommen SR; Nishimura RA; Schaff HV; Kim CS; Ackerman MJ J Cardiovasc Transl Res; 2019 Oct; 12(5):394-403. PubMed ID: 30796699 [TBL] [Abstract][Full Text] [Related]
7. Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes. Ramachandra CJA; Kp MMJ; Chua J; Hernandez-Resendiz S; Liehn EA; Knöll R; Gan LM; Michaëlsson E; Jonsson MKB; Ryden-Markinhuhta K; Bhat RV; Fritsche-Danielson R; Lin YH; Sadayappan S; Tang HC; Wong P; Shim W; Hausenloy DJ Cardiovasc Res; 2022 Jan; 118(2):517-530. PubMed ID: 33705529 [TBL] [Abstract][Full Text] [Related]
8. Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes. Monteiro da Rocha A; Guerrero-Serna G; Helms A; Luzod C; Mironov S; Russell M; Jalife J; Day SM; Smith GD; Herron TJ J Mol Cell Cardiol; 2016 Oct; 99():197-206. PubMed ID: 27620334 [TBL] [Abstract][Full Text] [Related]
10. Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells. Han L; Li Y; Tchao J; Kaplan AD; Lin B; Li Y; Mich-Basso J; Lis A; Hassan N; London B; Bett GC; Tobita K; Rasmusson RL; Yang L Cardiovasc Res; 2014 Nov; 104(2):258-69. PubMed ID: 25209314 [TBL] [Abstract][Full Text] [Related]
11. Phenotypic Screening Using Patient-Derived Induced Pluripotent Stem Cells Identified Pyr3 as a Candidate Compound for the Treatment of Infantile Hypertrophic Cardiomyopathy. Sakai T; Naito AT; Kuramoto Y; Ito M; Okada K; Higo T; Nakagawa A; Shibamoto M; Yamaguchi T; Sumida T; Nomura S; Umezawa A; Miyagawa S; Sawa Y; Morita H; Lee JK; Shiojima I; Sakata Y; Komuro I Int Heart J; 2018 Sep; 59(5):1096-1105. PubMed ID: 30101858 [TBL] [Abstract][Full Text] [Related]
12. Modeling hypertrophic cardiomyopathy with human cardiomyocytes derived from induced pluripotent stem cells. Li J; Feng X; Wei X Stem Cell Res Ther; 2022 Jun; 13(1):232. PubMed ID: 35659761 [TBL] [Abstract][Full Text] [Related]
13. Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction. Kinnear C; Said A; Meng G; Zhao Y; Wang EY; Rafatian N; Parmar N; Wei W; Billia F; Simmons CA; Radisic M; Ellis J; Mital S Cell Rep Med; 2024 May; 5(5):101520. PubMed ID: 38642550 [TBL] [Abstract][Full Text] [Related]
14. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Ma N; Zhang JZ; Itzhaki I; Zhang SL; Chen H; Haddad F; Kitani T; Wilson KD; Tian L; Shrestha R; Wu H; Lam CK; Sayed N; Wu JC Circulation; 2018 Dec; 138(23):2666-2681. PubMed ID: 29914921 [TBL] [Abstract][Full Text] [Related]
15. Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human Pioner JM; Vitale G; Steczina S; Langione M; Margara F; Santini L; Giardini F; Lazzeri E; Piroddi N; Scellini B; Palandri C; Schuldt M; Spinelli V; Girolami F; Mazzarotto F; van der Velden J; Cerbai E; Tesi C; Olivotto I; Bueno-Orovio A; Sacconi L; Coppini R; Ferrantini C; Regnier M; Poggesi C Circ Res; 2023 Mar; 132(5):628-644. PubMed ID: 36744470 [TBL] [Abstract][Full Text] [Related]
16. Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for Kondo T; Higo S; Shiba M; Kohama Y; Kameda S; Tabata T; Inoue H; Okuno S; Ogawa S; Nakamura S; Takeda M; Ito E; Li J; Liu L; Kuramoto Y; Lee JK; Takashima S; Miyagawa S; Sawa Y; Hikoso S; Sakata Y Circ Genom Precis Med; 2022 Oct; 15(5):e003522. PubMed ID: 35861968 [TBL] [Abstract][Full Text] [Related]
17. Applying Patient-Specific Induced Pluripotent Stem Cells to Create a Model of Hypertrophic Cardiomyopathy. Dementyeva EV; Medvedev SP; Kovalenko VR; Vyatkin YV; Kretov EI; Slotvitsky MM; Shtokalo DN; Pokushalov EA; Zakian SM Biochemistry (Mosc); 2019 Mar; 84(3):291-298. PubMed ID: 31221067 [TBL] [Abstract][Full Text] [Related]
18. Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling. Vučković S; Dinani R; Nollet EE; Kuster DWD; Buikema JW; Houtkooper RH; Nabben M; van der Velden J; Goversen B Stem Cell Res Ther; 2022 Jul; 13(1):332. PubMed ID: 35870954 [TBL] [Abstract][Full Text] [Related]
19. Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation. Li S; Pan H; Tan C; Sun Y; Song Y; Zhang X; Yang W; Wang X; Li D; Dai Y; Ma Q; Xu C; Zhu X; Kang L; Fu Y; Xu X; Shu J; Zhou N; Han F; Qin D; Huang W; Liu Z; Yan Q Stem Cell Reports; 2018 Mar; 10(3):808-821. PubMed ID: 29456182 [TBL] [Abstract][Full Text] [Related]
20. Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice. Flenner F; Geertz B; Reischmann-Düsener S; Weinberger F; Eschenhagen T; Carrier L; Friedrich FW J Physiol; 2017 Jun; 595(12):3987-3999. PubMed ID: 28090637 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]