These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 39024967)

  • 1. Optimization of pyrazolopyridine 4-carboxamides with potent antimalarial activity for which resistance is associated with the P. falciparum transporter ABCI3.
    Calic PPS; Ashton TD; Mansouri M; Loi K; Jarman KE; Qiu D; Lehane AM; Roy S; Rao GP; Maity B; Wittlin S; Crespo B; Gamo FJ; Deni I; Fidock DA; Chowdury M; de Koning-Ward TF; Cowman AF; Jackson PF; Baud D; Brand S; Laleu B; Sleebs BE
    Eur J Med Chem; 2024 Oct; 276():116677. PubMed ID: 39024967
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.
    Le Manach C; Paquet T; Brunschwig C; Njoroge M; Han Z; Gonzàlez Cabrera D; Bashyam S; Dhinakaran R; Taylor D; Reader J; Botha M; Churchyard A; Lauterbach S; Coetzer TL; Birkholtz LM; Meister S; Winzeler EA; Waterson D; Witty MJ; Wittlin S; Jiménez-Díaz MB; Santos Martínez M; Ferrer S; Angulo-Barturen I; Street LJ; Chibale K
    J Med Chem; 2015 Nov; 58(21):8713-22. PubMed ID: 26502160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-
    Eagon S; Hammill JT; Sigal M; Ahn KJ; Tryhorn JE; Koch G; Belanger B; Chaplan CA; Loop L; Kashtanova AS; Yniguez K; Lazaro H; Wilkinson SP; Rice AL; Falade MO; Takahashi R; Kim K; Cheung A; DiBernardo C; Kimball JJ; Winzeler EA; Eribez K; Mittal N; Gamo FJ; Crespo B; Churchyard A; García-Barbazán I; Baum J; Anderson MO; Laleu B; Guy RK
    J Med Chem; 2020 Oct; 63(20):11902-11919. PubMed ID: 32945666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity.
    Bailey BL; Nguyen W; Ngo A; Goodman CD; Gancheva MR; Favuzza P; Sanz LM; Gamo FJ; Lowes KN; McFadden GI; Wilson DW; Laleu B; Brand S; Jackson PF; Cowman AF; Sleebs BE
    Bioorg Chem; 2021 Oct; 115():105244. PubMed ID: 34452759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and anti-P. falciparum activity of pyrazolopyridine-sulfonamide derivatives.
    Silva TB; Bernardino AMR; Ferreira MLG; Rogerio KR; Carvalho LJM; Boechat N; Pinheiro LCS
    Bioorg Med Chem; 2016 Sep; 24(18):4492-4498. PubMed ID: 27485600
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, Structure-Activity Relationship, and Antimalarial Efficacy of 6-Chloro-2-arylvinylquinolines.
    Huang G; Murillo Solano C; Melendez J; Shaw J; Collins J; Banks R; Arshadi AK; Boonhok R; Min H; Miao J; Chakrabarti D; Yuan Y
    J Med Chem; 2020 Oct; 63(20):11756-11785. PubMed ID: 32959656
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.
    Nguyen W; Dans MG; Ngo A; Gancheva MR; Romeo O; Duffy S; de Koning-Ward TF; Lowes KN; Sabroux HJ; Avery VM; Wilson DW; Gilson PR; Sleebs BE
    Eur J Med Chem; 2021 Mar; 214():113253. PubMed ID: 33610028
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance.
    Murithi JM; Deni I; Pasaje CFA; Okombo J; Bridgford JL; Gnädig NF; Edwards RL; Yeo T; Mok S; Burkhard AY; Coburn-Flynn O; Istvan ES; Sakata-Kato T; Gomez-Lorenzo MG; Cowell AN; Wicht KJ; Le Manach C; Kalantarov GF; Dey S; Duffey M; Laleu B; Lukens AK; Ottilie S; Vanaerschot M; Trakht IN; Gamo FJ; Wirth DF; Goldberg DE; Odom John AR; Chibale K; Winzeler EA; Niles JC; Fidock DA
    Cell Chem Biol; 2022 May; 29(5):824-839.e6. PubMed ID: 34233174
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957.
    Miguel-Blanco C; Murithi JM; Benavente ED; Angrisano F; Sala KA; van Schalkwyk DA; Vanaerschot M; Schwach F; Fuchter MJ; Billker O; Sutherland CJ; Campino SG; Clark TG; Blagborough AM; Fidock DA; Herreros E; Gamo FJ; Baum J; Delves MJ
    Sci Rep; 2021 Jan; 11(1):1888. PubMed ID: 33479319
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and in vitro evaluation of novel 8-aminoquinoline-pyrazolopyrimidine hybrids as potent antimalarial agents.
    Kannan M; Raichurkar AV; Khan FR; Iyer PS
    Bioorg Med Chem Lett; 2015 Mar; 25(5):1100-3. PubMed ID: 25650255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites.
    Dorjsuren D; Eastman RT; Wicht KJ; Jansen D; Talley DC; Sigmon BA; Zakharov AV; Roncal N; Girvin AT; Antonova-Koch Y; Will PM; Shah P; Sun H; Klumpp-Thomas C; Mok S; Yeo T; Meister S; Marugan JJ; Ross LS; Xu X; Maloney DJ; Jadhav A; Mott BT; Sciotti RJ; Winzeler EA; Waters NC; Campbell RF; Huang W; Simeonov A; Fidock DA
    Sci Rep; 2021 Jan; 11(1):2121. PubMed ID: 33483532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Designing novel inhibitors against falcipain-2 of Plasmodium falciparum.
    Himangini ; Pathak DP; Sharma V; Kumar S
    Bioorg Med Chem Lett; 2018 May; 28(9):1566-1569. PubMed ID: 29602682
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4.
    Ashton TD; Dans MG; Favuzza P; Ngo A; Lehane AM; Zhang X; Qiu D; Chandra Maity B; De N; Schindler KA; Yeo T; Park H; Uhlemann AC; Churchyard A; Baum J; Fidock DA; Jarman KE; Lowes KN; Baud D; Brand S; Jackson PF; Cowman AF; Sleebs BE
    J Med Chem; 2023 Mar; 66(5):3540-3565. PubMed ID: 36812492
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites.
    Bosson-Vanga H; Primas N; Franetich JF; Lavazec C; Gomez L; Ashraf K; Tefit M; Soulard V; Dereuddre-Bosquet N; Le Grand R; Donnette M; Mustière R; Amanzougaghene N; Tajeri S; Suzanne P; Malzert-Fréon A; Rault S; Vanelle P; Hutter S; Cohen A; Snounou G; Roques P; Azas N; Lagardère P; Lisowski V; Masurier N; Nguyen M; Paloque L; Benoit-Vical F; Verhaeghe P; Mazier D
    Microbiol Spectr; 2021 Oct; 9(2):e0027421. PubMed ID: 34724729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of thymol-based pyrazolines: An effort to perceive novel potent-antimalarials.
    Raghuvanshi DS; Verma N; Singh SV; Khare S; Pal A; Negi AS
    Bioorg Chem; 2019 Jul; 88():102933. PubMed ID: 31048119
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 6'-chloro-N-methyl-5'-(phenylsulfonamido)-[3,3'-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium.
    Liang X; Jiang Z; Huang Z; Li F; Chen C; Hu C; Wang W; Hu Z; Liu Q; Wang B; Wang L; Qi Z; Liu J; Jiang L; Liu Q
    Eur J Med Chem; 2020 Feb; 188():112012. PubMed ID: 31911293
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antimalarial evaluation of 1, 3, 5-trisubstituted pyrazolines.
    Acharya BN; Saraswat D; Tiwari M; Shrivastava AK; Ghorpade R; Bapna S; Kaushik MP
    Eur J Med Chem; 2010 Feb; 45(2):430-8. PubMed ID: 19926176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
    Skytte DM; Nielsen SF; Chen M; Zhai L; Olsen CE; Christensen SB
    J Med Chem; 2006 Jan; 49(1):436-40. PubMed ID: 16392829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclopropyl carboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screen.
    Sanz LM; Jiménez-Díaz MB; Crespo B; De-Cozar C; Almela MJ; Angulo-Barturen I; Castañeda P; Ibañez J; Fernández EP; Ferrer S; Herreros E; Lozano S; Martínez MS; Rueda L; Burrows JN; García-Bustos JF; Gamo FJ
    Antimicrob Agents Chemother; 2011 Dec; 55(12):5740-5. PubMed ID: 21968362
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
    Biagini GA; Fisher N; Shone AE; Mubaraki MA; Srivastava A; Hill A; Antoine T; Warman AJ; Davies J; Pidathala C; Amewu RK; Leung SC; Sharma R; Gibbons P; Hong DW; Pacorel B; Lawrenson AS; Charoensutthivarakul S; Taylor L; Berger O; Mbekeani A; Stocks PA; Nixon GL; Chadwick J; Hemingway J; Delves MJ; Sinden RE; Zeeman AM; Kocken CH; Berry NG; O'Neill PM; Ward SA
    Proc Natl Acad Sci U S A; 2012 May; 109(21):8298-303. PubMed ID: 22566611
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.