These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 39025409)

  • 1. Inhibition of PLA2G4A attenuated valproic acid- induced lysosomal membrane permeabilization and restored impaired autophagic flux: Implications for hepatotoxicity.
    Wang ML; Zhang YJ; He DL; Li T; Zhao MM; Zhao LM
    Biochem Pharmacol; 2024 Sep; 227():116438. PubMed ID: 39025409
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma.
    Sarkar C; Jones JW; Hegdekar N; Thayer JA; Kumar A; Faden AI; Kane MA; Lipinski MM
    Autophagy; 2020 Mar; 16(3):466-485. PubMed ID: 31238788
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combination of metformin and sub-therapeutic dose of valproic acid prevent valproic acid-induced toxicity in animal model of epilepsy.
    Jamal M; Azam M; Simjee SU
    Drug Chem Toxicol; 2024 May; 47(3):287-295. PubMed ID: 36650908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A new approach on valproic acid induced hepatotoxicity: involvement of lysosomal membrane leakiness and cellular proteolysis.
    Pourahmad J; Eskandari MR; Kaghazi A; Shaki F; Shahraki J; Fard JK
    Toxicol In Vitro; 2012 Jun; 26(4):545-51. PubMed ID: 22342442
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of PLA2G4E/cPLA2 promotes survival of random skin flaps by alleviating Lysosomal membrane permeabilization-Induced necroptosis.
    Lou J; Wang X; Zhang H; Yu G; Ding J; Zhu X; Li Y; Wu Y; Xu H; Xu H; Gao W; Xiao J; Zhou K
    Autophagy; 2022 Aug; 18(8):1841-1863. PubMed ID: 34872436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver.
    Lee MH; Kim M; Lee BH; Kim JH; Kang KS; Kim HL; Yoon BI; Chung H; Kong G; Lee MO
    Toxicol Appl Pharmacol; 2008 Feb; 226(3):271-84. PubMed ID: 17963808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ROS-mediated lysosomal membrane permeabilization and autophagy inhibition regulate bleomycin-induced cellular senescence.
    Qi Z; Yang W; Xue B; Chen T; Lu X; Zhang R; Li Z; Zhao X; Zhang Y; Han F; Kong X; Liu R; Yao X; Jia R; Feng S
    Autophagy; 2024 Sep; 20(9):2000-2016. PubMed ID: 38762757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cadmium-induced cytotoxicity in mouse liver cells is associated with the disruption of autophagic flux via inhibiting the fusion of autophagosomes and lysosomes.
    Zou H; Wang T; Yuan J; Sun J; Yuan Y; Gu J; Liu X; Bian J; Liu Z
    Toxicol Lett; 2020 Mar; 321():32-43. PubMed ID: 31862506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxidative stress as a mechanism of valproic acid-associated hepatotoxicity.
    Chang TK; Abbott FS
    Drug Metab Rev; 2006; 38(4):627-39. PubMed ID: 17145692
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity.
    Chen Y; Zhou J; Xu S; Liu M; Wang M; Ma Y; Zhao M; Wang Z; Guo Y; Zhao L
    Biochem Pharmacol; 2019 Dec; 170():113669. PubMed ID: 31628911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury.
    Li Y; Jones JW; M C Choi H; Sarkar C; Kane MA; Koh EY; Lipinski MM; Wu J
    Cell Death Dis; 2019 Jul; 10(7):531. PubMed ID: 31296844
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT).
    Gutierrez EM; Seebacher NA; Arzuman L; Kovacevic Z; Lane DJ; Richardson V; Merlot AM; Lok H; Kalinowski DS; Sahni S; Jansson PJ; Richardson DR
    Biochim Biophys Acta; 2016 Jul; 1863(7 Pt A):1665-81. PubMed ID: 27102538
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats.
    Zhang LF; Liu LS; Chu XM; Xie H; Cao LJ; Guo C; A JY; Cao B; Li MJ; Wang GJ; Hao HP
    Acta Pharmacol Sin; 2014 Mar; 35(3):363-72. PubMed ID: 24442146
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of Nrf2 activation and NF-κB inhibition in valproic acid induced hepatotoxicity and in diammonium glycyrrhizinate induced protection in mice.
    Jin J; Xiong T; Hou X; Sun X; Liao J; Huang Z; Huang M; Zhao Z
    Food Chem Toxicol; 2014 Nov; 73():95-104. PubMed ID: 25152329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury.
    Zheng Z; Wu Y; Li Z; Ye L; Lu Q; Zhou Y; Yuan Y; Jiang T; Xie L; Liu Y; Chen D; Ye J; Nimlamool W; Zhang H; Xiao J
    J Neurochem; 2020 Aug; 154(3):284-300. PubMed ID: 31602651
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diclofenac impairs autophagic flux via oxidative stress and lysosomal dysfunction: Implications for hepatotoxicity.
    Jung SH; Lee W; Park SH; Lee KY; Choi YJ; Choi S; Kang D; Kim S; Chang TS; Hong SS; Lee BH
    Redox Biol; 2020 Oct; 37():101751. PubMed ID: 33080439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Valproate induced hepatic steatosis by enhanced fatty acid uptake and triglyceride synthesis.
    Bai X; Hong W; Cai P; Chen Y; Xu C; Cao D; Yu W; Zhao Z; Huang M; Jin J
    Toxicol Appl Pharmacol; 2017 Jun; 324():12-25. PubMed ID: 28366540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status.
    Tang W; Borel AG; Fujimiya T; Abbott FS
    Chem Res Toxicol; 1995; 8(5):671-82. PubMed ID: 7548749
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Butyrate prevents valproate-induced liver injury: In vitro and in vivo evidence.
    Pirozzi C; Lama A; Annunziata C; Cavaliere G; De Caro C; Citraro R; Russo E; Tallarico M; Iannone M; Ferrante MC; Mollica MP; Mattace Raso G; De Sarro G; Calignano A; Meli R
    FASEB J; 2020 Jan; 34(1):676-690. PubMed ID: 31914696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BAX channel activity mediates lysosomal disruption linked to Parkinson disease.
    Bové J; Martínez-Vicente M; Dehay B; Perier C; Recasens A; Bombrun A; Antonsson B; Vila M
    Autophagy; 2014 May; 10(5):889-900. PubMed ID: 24686337
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.