These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
135 related articles for article (PubMed ID: 39094276)
1. Design, synthesis, and biological evaluation of RSL3-based GPX4 degraders with hydrophobic tags. Ning Y; Zhu Z; Wang Y; Fan X; Wang J; Qian H; Qiu X; Wang Y Eur J Med Chem; 2024 Nov; 277():116719. PubMed ID: 39094276 [TBL] [Abstract][Full Text] [Related]
2. A potent GPX4 degrader to induce ferroptosis in HT1080 cells. Song H; Liang J; Guo Y; Liu Y; Sa K; Yan G; Xu W; Xu W; Chen L; Li H Eur J Med Chem; 2024 Feb; 265():116110. PubMed ID: 38194774 [TBL] [Abstract][Full Text] [Related]
3. Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders. Li X; Hu M; Zhang Y; Hua H; Sun Y; Xiang Q; Zhu D Bioorg Chem; 2024 Mar; 144():107115. PubMed ID: 38232684 [TBL] [Abstract][Full Text] [Related]
4. Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells. Wang H; Wang C; Li B; Zheng C; Liu G; Liu Z; Zhang L; Xu P Eur J Med Chem; 2023 Jun; 254():115343. PubMed ID: 37087895 [TBL] [Abstract][Full Text] [Related]
5. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Huang W; Guo Y; Qian Y; Liu X; Li G; Wang J; Yang X; Wu M; Fan Y; Luo H; Chen Y; Zhang L; Yang N; Liu Z; Liu Y Eur J Med Chem; 2024 Oct; 276():116670. PubMed ID: 39018922 [TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biological evaluation of artesunate-Se derivatives as anticancer agents by inducing GPX4-mediated ferroptosis. Ren M; Liang S; Lin S; Huang R; Chen Y; Zhang Y; Xu Y Bioorg Chem; 2024 Nov; 152():107733. PubMed ID: 39180865 [TBL] [Abstract][Full Text] [Related]
7. Research progress on GPX4 targeted compounds. Li B; Cheng K; Wang T; Peng X; Xu P; Liu G; Xue D; Jiao N; Wang C Eur J Med Chem; 2024 Aug; 274():116548. PubMed ID: 38838547 [TBL] [Abstract][Full Text] [Related]
8. Dual degradation mechanism of GPX4 degrader in induction of ferroptosis exerting anti-resistant tumor effect. Wang C; Zheng C; Wang H; Shui S; Jin H; Liu G; Xu F; Liu Z; Zhang L; Sun D; Xu P Eur J Med Chem; 2023 Feb; 247():115072. PubMed ID: 36603510 [TBL] [Abstract][Full Text] [Related]
9. Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer. Xu C; Xiao Z; Wang J; Lai H; Zhang T; Guan Z; Xia M; Chen M; Ren L; He Y; Gao Y; Zhao C J Med Chem; 2021 Sep; 64(18):13312-13326. PubMed ID: 34506134 [TBL] [Abstract][Full Text] [Related]
10. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization. Zheng C; Wang C; Sun D; Wang H; Li B; Liu G; Liu Z; Zhang L; Xu P Eur J Med Chem; 2023 Jul; 255():115393. PubMed ID: 37098297 [TBL] [Abstract][Full Text] [Related]
11. Directly targeting glutathione peroxidase 4 may be more effective than disrupting glutathione on ferroptosis-based cancer therapy. Wei Y; Lv H; Shaikh AB; Han W; Hou H; Zhang Z; Wang S; Shang P Biochim Biophys Acta Gen Subj; 2020 Apr; 1864(4):129539. PubMed ID: 31958545 [TBL] [Abstract][Full Text] [Related]
12. Targeting GPX4 in ferroptosis and cancer: chemical strategies and challenges. Liu J; Tang D; Kang R Trends Pharmacol Sci; 2024 Aug; 45(8):666-670. PubMed ID: 38866667 [TBL] [Abstract][Full Text] [Related]
13. RSL3 Drives Ferroptosis through NF- Li S; He Y; Chen K; Sun J; Zhang L; He Y; Yu H; Li Q Oxid Med Cell Longev; 2021; 2021():2915019. PubMed ID: 34987700 [TBL] [Abstract][Full Text] [Related]
14. Heat Shock Protein 90 Interactome-Mediated Proteolysis Targeting Chimera (HIM-PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis. Dong J; Ma F; Cai M; Cao F; Li H; Liang H; Li Y; Ding G; Li J; Cheng X; Qin JJ J Med Chem; 2024 Sep; 67(18):16712-16736. PubMed ID: 39230973 [TBL] [Abstract][Full Text] [Related]
15. Discovery of a first-in-class degrader for the protein arginine methyltransferase 6 (PRMT6). Yang H; Zhang Q; Zhou S; Hu Z; Tang Q; Li Z; Feng Q; Yu L Bioorg Chem; 2024 Jul; 148():107439. PubMed ID: 38754310 [TBL] [Abstract][Full Text] [Related]
16. Inactivation of the glutathione peroxidase GPx4 by the ferroptosis-inducing molecule RSL3 requires the adaptor protein 14-3-3ε. Vučković AM; Bosello Travain V; Bordin L; Cozza G; Miotto G; Rossetto M; Toppo S; Venerando R; Zaccarin M; Maiorino M; Ursini F; Roveri A FEBS Lett; 2020 Feb; 594(4):611-624. PubMed ID: 31581313 [TBL] [Abstract][Full Text] [Related]
17. Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer. Shin D; Kim EH; Lee J; Roh JL Free Radic Biol Med; 2018 Dec; 129():454-462. PubMed ID: 30339884 [TBL] [Abstract][Full Text] [Related]
18. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. Chen T; Leng J; Tan J; Zhao Y; Xie S; Zhao S; Yan X; Zhu L; Luo J; Kong L; Yin Y J Med Chem; 2023 Jul; 66(14):10036-10059. PubMed ID: 37452764 [TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and biological evaluation of nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation. Liu SJ; Zhao Q; Peng C; Mao Q; Wu F; Zhang FH; Feng QS; He G; Han B Eur J Med Chem; 2021 May; 217():113359. PubMed ID: 33725632 [TBL] [Abstract][Full Text] [Related]
20. Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis. Imai H; Matsuoka M; Kumagai T; Sakamoto T; Koumura T Curr Top Microbiol Immunol; 2017; 403():143-170. PubMed ID: 28204974 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]