BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 3910110)

  • 1. Engineering of tyrosyl tRNA synthetase.
    Bedouelle H; Carter P; Waye MM; Winter G; Lowe DM; Wilkinson AJ; Fersht AR
    Biochimie; 1985; 67(7-8):737-43. PubMed ID: 3910110
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus).
    Carter PJ; Winter G; Wilkinson AJ; Fersht AR
    Cell; 1984 Oct; 38(3):835-40. PubMed ID: 6488318
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Natural variation of tyrosyl-tRNA synthetase and comparison with engineered mutants.
    Jones MD; Lowe DM; Borgford T; Fersht AR
    Biochemistry; 1986 Apr; 25(8):1887-91. PubMed ID: 3011073
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Internal thermodynamics of position 51 mutants and natural variants of tyrosyl-tRNA synthetase.
    Ho CK; Fersht AR
    Biochemistry; 1986 Apr; 25(8):1891-7. PubMed ID: 3518795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cloning and amplified expression of the tyrosyl-tRNA synthetase genes of Bacillus stearothermophilus and Escherichia coli.
    Barker DG
    Eur J Biochem; 1982 Jul; 125(2):357-60. PubMed ID: 6749496
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A large increase in enzyme-substrate affinity by protein engineering.
    Wilkinson AJ; Fersht AR; Blow DM; Carter P; Winter G
    Nature; 1984 Jan 12-18; 307(5947):187-8. PubMed ID: 6690998
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding.
    Winter G; Fersht AR; Wilkinson AJ; Zoller M; Smith M
    Nature; 1982 Oct; 299(5885):756-8. PubMed ID: 6811955
    [No Abstract]   [Full Text] [Related]  

  • 8. Fine structure-activity analysis of mutations at position 51 of tyrosyl-tRNA synthetase.
    Fersht AR; Wilkinson AJ; Carter P; Winter G
    Biochemistry; 1985 Oct; 24(21):5858-61. PubMed ID: 3002425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A transcription terminator in the 5' non-coding region of the tyrosyl tRNA synthetase gene from Bacillus stearothermophilus.
    Waye MM; Winter G
    Eur J Biochem; 1986 Aug; 158(3):505-10. PubMed ID: 3525162
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A model of synthetase/transfer RNA interaction as deduced by protein engineering.
    Bedouelle H; Winter G
    Nature; 1986 Mar 27-Apr 2; 320(6060):371-3. PubMed ID: 3960121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis.
    Fersht AR
    Biochemistry; 1987 Dec; 26(25):8031-7. PubMed ID: 3442641
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Correlating amino acid conservation with function in tyrosyl-tRNA synthetase.
    Xin Y; Li W; Dwyer DS; First EA
    J Mol Biol; 2000 Oct; 303(2):287-98. PubMed ID: 11023793
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationships in engineered proteins: characterization of disruptive deletions in the alpha-ammonium group binding site of tyrosyl-tRNA synthetase.
    Lowe DM; Winter G; Fersht AR
    Biochemistry; 1987 Sep; 26(19):6038-43. PubMed ID: 3480006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface.
    Jones DH; McMillan AJ; Fersht AR; Winter G
    Biochemistry; 1985 Oct; 24(21):5852-7. PubMed ID: 4084496
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deletion mutagenesis using an 'M13 splint': the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate.
    Waye MM; Winter G; Wilkinson AJ; Fersht AR
    EMBO J; 1983; 2(10):1827-9. PubMed ID: 6315404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation.
    Wilkinson AJ; Fersht AR; Blow DM; Winter G
    Biochemistry; 1983 Jul; 22(15):3581-6. PubMed ID: 6615786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic dissection of tyrosyl-tRNA synthetase.
    Winter G; Carter P; Waye MM; Blow DM; Wilkinson AJ; Shi JP; Fersht AR
    Biochem Soc Trans; 1984 Apr; 12(2):224-5. PubMed ID: 6724115
    [No Abstract]   [Full Text] [Related]  

  • 18. Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements.
    Lowe DM; Fersht AR; Wilkinson AJ; Carter P; Winter G
    Biochemistry; 1985 Sep; 24(19):5106-9. PubMed ID: 4074680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Asymmetry of tyrosyl-tRNA synthetase in solution.
    Ward WH; Fersht AR
    Biochemistry; 1988 Feb; 27(3):1041-9. PubMed ID: 3365365
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering.
    Leatherbarrow RJ; Fersht AR; Winter G
    Proc Natl Acad Sci U S A; 1985 Dec; 82(23):7840-4. PubMed ID: 3865201
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.