These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 39110804)

  • 1. AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1.
    Díaz-Holguín A; Saarinen M; Vo DD; Sturchio A; Branzell N; Cabeza de Vaca I; Hu H; Mitjavila-Domènech N; Lindqvist A; Baranczewski P; Millan MJ; Yang Y; Carlsson J; Svenningsson P
    Sci Adv; 2024 Aug; 10(32):eadn1524. PubMed ID: 39110804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling.
    Grossi G; Scarano N; Musumeci F; Tonelli M; Kanov E; Carbone A; Fossa P; Gainetdinov RR; Cichero E; Schenone S
    Molecules; 2024 Apr; 29(8):. PubMed ID: 38675561
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
    Tonelli M; Espinoza S; Gainetdinov RR; Cichero E
    Eur J Med Chem; 2017 Feb; 127():781-792. PubMed ID: 27823885
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting species-specific trace amine-associated receptor 1 ligands: to date perspective of the rational drug design process.
    Cichero E; Tonelli M
    Future Med Chem; 2017 Sep; 9(13):1507-1527. PubMed ID: 28791911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands.
    Scarano N; Espinoza S; Brullo C; Cichero E
    Int J Mol Sci; 2024 Jul; 25(15):. PubMed ID: 39125796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of potential TAAR1 agonist targeting neurological and psychiatric disorders: An in silico approach.
    Garisetti V; Dhanabalan AK; Dasararaju G
    Int J Biol Macromol; 2024 Apr; 264(Pt 2):130528. PubMed ID: 38431013
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Newly identified structures of trace-amine associated receptor-1 (TAAR1) will aid discovery of next generation neuropsychiatric drugs.
    Nair PC; Shajan B; Bastiampillai T
    Mol Psychiatry; 2024 Jun; 29(6):1925-1928. PubMed ID: 38326558
    [No Abstract]   [Full Text] [Related]  

  • 8. Further insights into the pharmacology of the human trace amine-associated receptors: discovery of novel ligands for TAAR1 by a virtual screening approach.
    Cichero E; Espinoza S; Franchini S; Guariento S; Brasili L; Gainetdinov RR; Fossa P
    Chem Biol Drug Des; 2014 Dec; 84(6):712-20. PubMed ID: 24894156
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.
    Hu LA; Zhou T; Ahn J; Wang S; Zhou J; Hu Y; Liu Q
    Biochem J; 2009 Oct; 424(1):39-45. PubMed ID: 19725810
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TAAR1 and Psychostimulant Addiction.
    Liu J; Wu R; Li JX
    Cell Mol Neurobiol; 2020 Mar; 40(2):229-238. PubMed ID: 31974906
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics.
    Revel FG; Moreau JL; Gainetdinov RR; Ferragud A; Velázquez-Sánchez C; Sotnikova TD; Morairty SR; Harmeier A; Groebke Zbinden K; Norcross RD; Bradaia A; Kilduff TS; Biemans B; Pouzet B; Caron MG; Canales JJ; Wallace TL; Wettstein JG; Hoener MC
    Biol Psychiatry; 2012 Dec; 72(11):934-42. PubMed ID: 22705041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ligand recognition and G-protein coupling of trace amine receptor TAAR1.
    Xu Z; Guo L; Yu J; Shen S; Wu C; Zhang W; Zhao C; Deng Y; Tian X; Feng Y; Hou H; Su L; Wang H; Guo S; Wang H; Wang K; Chen P; Zhao J; Zhang X; Yong X; Cheng L; Liu L; Yang S; Yang F; Wang X; Yu X; Xu Y; Sun JP; Yan W; Shao Z
    Nature; 2023 Dec; 624(7992):672-681. PubMed ID: 37935376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays.
    Cichero E; Francesconi V; Casini B; Casale M; Kanov E; Gerasimov AS; Sukhanov I; Savchenko A; Espinoza S; Gainetdinov RR; Tonelli M
    Pharmaceuticals (Basel); 2023 Nov; 16(11):. PubMed ID: 38004497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How accurately can one predict drug binding modes using AlphaFold models?
    Karelina M; Noh JJ; Dror RO
    Elife; 2023 Dec; 12():. PubMed ID: 38131311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In Vitro Characterization of Psychoactive Substances at Rat, Mouse, and Human Trace Amine-Associated Receptor 1.
    Simmler LD; Buchy D; Chaboz S; Hoener MC; Liechti ME
    J Pharmacol Exp Ther; 2016 Apr; 357(1):134-44. PubMed ID: 26791601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice.
    Panas HN; Lynch LJ; Vallender EJ; Xie Z; Chen GL; Lynn SK; Scanlan TS; Miller GM
    J Neurosci Res; 2010 Jul; 88(9):1962-9. PubMed ID: 20155805
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies.
    Dedic N; Dworak H; Zeni C; Rutigliano G; Howes OD
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34947997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists.
    Chiellini G; Nesi G; Digiacomo M; Malvasi R; Espinoza S; Sabatini M; Frascarelli S; Laurino A; Cichero E; Macchia M; Gainetdinov RR; Fossa P; Raimondi L; Zucchi R; Rapposelli S
    J Med Chem; 2015 Jun; 58(12):5096-107. PubMed ID: 26010728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics.
    Black SW; Schwartz MD; Chen TM; Hoener MC; Kilduff TS
    Biol Psychiatry; 2017 Nov; 82(9):623-633. PubMed ID: 27919403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity.
    Revel FG; Moreau JL; Gainetdinov RR; Bradaia A; Sotnikova TD; Mory R; Durkin S; Zbinden KG; Norcross R; Meyer CA; Metzler V; Chaboz S; Ozmen L; Trube G; Pouzet B; Bettler B; Caron MG; Wettstein JG; Hoener MC
    Proc Natl Acad Sci U S A; 2011 May; 108(20):8485-90. PubMed ID: 21525407
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.