These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 39124901)

  • 1. Unveiling Allosteric Regulation and Binding Mechanism of BRD9 through Molecular Dynamics Simulations and Markov Modeling.
    Wang B; Wang J; Yang W; Zhao L; Wei B; Chen J
    Molecules; 2024 Jul; 29(15):. PubMed ID: 39124901
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding Mechanism of Inhibitors to BRD4 and BRD9 Decoded by Multiple Independent Molecular Dynamics Simulations and Deep Learning.
    Wang J; Yang W; Zhao L; Wei B; Chen J
    Molecules; 2024 Apr; 29(8):. PubMed ID: 38675678
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insight into selective mechanism of class of I-BRD9 inhibitors toward BRD9 based on molecular dynamics simulations.
    Su J; Liu X; Zhang S; Yan F; Zhang Q; Chen J
    Chem Biol Drug Des; 2019 Feb; 93(2):163-176. PubMed ID: 30225973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular mechanism study of several inhibitors binding to BRD9 bromodomain based on molecular simulations.
    Song LT; Tu J; Liu RR; Zhu M; Meng YJ; Zhai HL
    J Biomol Struct Dyn; 2019 Jul; 37(11):2970-2979. PubMed ID: 30058436
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Dynamics Simulations Combined with Markov Model to Explore the Effect of Allosteric Inhibitor Binding on Bromodomain-Containing Protein 4.
    Yang X; Gao Y; Cao F; Wang S
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446009
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanism of inhibitor bindings to bromodomain-containing protein 9 explored based on molecular dynamics simulations and calculations of binding free energies.
    Wang Y; Wang LF; Zhang LL; Sun HB; Zhao J
    SAR QSAR Environ Res; 2020 Feb; 31(2):149-170. PubMed ID: 31851834
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deciphering Selectivity Mechanism of BRD9 and TAF1(2) toward Inhibitors Based on Multiple Short Molecular Dynamics Simulations and MM-GBSA Calculations.
    Wang L; Wang Y; Yu Y; Liu D; Zhao J; Zhang L
    Molecules; 2023 Mar; 28(6):. PubMed ID: 36985555
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
    Theodoulou NH; Bamborough P; Bannister AJ; Becher I; Bit RA; Che KH; Chung CW; Dittmann A; Drewes G; Drewry DH; Gordon L; Grandi P; Leveridge M; Lindon M; Michon AM; Molnar J; Robson SC; Tomkinson NC; Kouzarides T; Prinjha RK; Humphreys PG
    J Med Chem; 2016 Feb; 59(4):1425-39. PubMed ID: 25856009
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into the Ligand Binding to Bromodomain-Containing Protein 9 (BRD9): A Guide to the Selection of Potential Binders by Computational Methods.
    De Vita S; Chini MG; Bifulco G; Lauro G
    Molecules; 2021 Nov; 26(23):. PubMed ID: 34885774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pan-cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours.
    Chen Y; Gao Z; Mohd-Ibrahim I; Yang H; Wu L; Fu Y; Deng Y
    Clin Transl Med; 2024 Feb; 14(2):e1543. PubMed ID: 38303608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of a hidden transient state in all bromodomain families.
    Raich L; Meier K; Günther J; Christ CD; Noé F; Olsson S
    Proc Natl Acad Sci U S A; 2021 Jan; 118(4):. PubMed ID: 33468647
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Research progress of selective small molecule bromodomain-containing protein 9 inhibitors.
    Hui M; Jian Z; Peiyuan Z; Zhenwei W; Huibin Z
    Future Med Chem; 2018 Apr; 10(8):895-906. PubMed ID: 29620420
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9.
    Klein DC; Lardo SM; Hainer SJ
    Cancer Res Commun; 2024 Jan; 4(1):237-252. PubMed ID: 38126767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenetic modulation by targeting bromodomain containing protein 9 (BRD9): Its therapeutic potential and selective inhibition.
    Ali MM; Naz S; Ashraf S; Knapp S; Ul-Haq Z
    Int J Biol Macromol; 2023 Mar; 230():123428. PubMed ID: 36709803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
    Karim RM; Chan A; Zhu JY; Schönbrunn E
    J Med Chem; 2020 Mar; 63(6):3227-3237. PubMed ID: 32091206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A computational insight into binding modes of inhibitors XD29, XD35, and XD28 to bromodomain-containing protein 4 based on molecular dynamics simulations.
    Su J; Liu X; Zhang S; Yan F; Zhang Q; Chen J
    J Biomol Struct Dyn; 2018 Apr; 36(5):1212-1224. PubMed ID: 28466681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insight into the structural mechanism for PKBα allosteric inhibition by molecular dynamics simulations and free energy calculations.
    Chen SF; Cao Y; Han S; Chen JZ
    J Mol Graph Model; 2014 Mar; 48():36-46. PubMed ID: 24374242
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Theoretical exploration of the binding selectivity of inhibitors to BRD7 and BRD9 with multiple short molecular dynamics simulations.
    Wang L; Wang Y; Zhao J; Yu Y; Kang N; Yang Z
    RSC Adv; 2022 Jun; 12(26):16663-16676. PubMed ID: 35754900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of Selective BRD9 Inhibitor via Integrated Computational Approach.
    Ali MM; Ashraf S; Nure-E-Alam M; Qureshi U; Khan KM; Ul-Haq Z
    Int J Mol Sci; 2022 Nov; 23(21):. PubMed ID: 36362300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing molecular mechanism of inhibitor bindings to bromodomain-containing protein 4 based on molecular dynamics simulations and principal component analysis.
    Wu SL; Wang LF; Sun HB; Wang W; Yu YX
    SAR QSAR Environ Res; 2020 Jul; 31(7):547-570. PubMed ID: 32657160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.