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2. Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma. Martinikova AS; Burocziova M; Stoyanov M; Macurek L Cells; 2020 Sep; 9(9):. PubMed ID: 32927737 [TBL] [Abstract][Full Text] [Related]
3. Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Nannenga B; Lu X; Dumble M; Van Maanen M; Nguyen TA; Sutton R; Kumar TR; Donehower LA Mol Carcinog; 2006 Aug; 45(8):594-604. PubMed ID: 16652371 [TBL] [Abstract][Full Text] [Related]
4. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Burocziova M; Burdova K; Martinikova AS; Kasparek P; Kleiblova P; Danielsen SA; Borecka M; Jenikova G; Janečková L; Pavel J; Zemankova P; Schneiderova M; Schwarzova L; Ticha I; Sun XF; Jiraskova K; Liska V; Vodickova L; Vodicka P; Sedlacek R; Kleibl Z; Lothe RA; Korinek V; Macurek L Cell Death Dis; 2019 Oct; 10(11):818. PubMed ID: 31659152 [TBL] [Abstract][Full Text] [Related]
5. PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. Martinikova AS; Stoyanov M; Oravetzova A; Kok YP; Yu S; Dobrovolna J; Janscak P; van Vugt M; Macurek L Mol Oncol; 2024 Jan; 18(1):6-20. PubMed ID: 37067201 [TBL] [Abstract][Full Text] [Related]
7. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D. Lu X; Nguyen TA; Donehower LA Cell Cycle; 2005 Aug; 4(8):1060-4. PubMed ID: 15970689 [TBL] [Abstract][Full Text] [Related]
8. DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase. Douarre C; Mergui X; Sidibe A; Gomez D; Alberti P; Mailliet P; Trentesaux C; Riou JF Nucleic Acids Res; 2013 Apr; 41(6):3588-99. PubMed ID: 23396447 [TBL] [Abstract][Full Text] [Related]
9. Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication. Sakai H; Fujigaki H; Mazur SJ; Appella E Cell Cycle; 2014; 13(6):1015-29. PubMed ID: 24552809 [TBL] [Abstract][Full Text] [Related]
10. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints. Lu X; Nannenga B; Donehower LA Genes Dev; 2005 May; 19(10):1162-74. PubMed ID: 15870257 [TBL] [Abstract][Full Text] [Related]
11. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity. Bulavin DV; Demidov ON; Saito S; Kauraniemi P; Phillips C; Amundson SA; Ambrosino C; Sauter G; Nebreda AR; Anderson CW; Kallioniemi A; Fornace AJ; Appella E Nat Genet; 2002 Jun; 31(2):210-5. PubMed ID: 12021785 [TBL] [Abstract][Full Text] [Related]
12. Inhibition of mutant PPM1D enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma. Akamandisa MP; Nie K; Nahta R; Hambardzumyan D; Castellino RC Neuro Oncol; 2019 Jun; 21(6):786-799. PubMed ID: 30852603 [TBL] [Abstract][Full Text] [Related]
13. Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients. Zajkowicz A; Butkiewicz D; Drosik A; Giglok M; Suwiński R; Rusin M Br J Cancer; 2015 Mar; 112(6):1114-20. PubMed ID: 25742468 [TBL] [Abstract][Full Text] [Related]
14. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. Pechackova S; Burdova K; Benada J; Kleiblova P; Jenikova G; Macurek L Oncotarget; 2016 Mar; 7(12):14458-75. PubMed ID: 26883108 [TBL] [Abstract][Full Text] [Related]
15. Homeostatic regulation of base excision repair by a p53-induced phosphatase: linking stress response pathways with DNA repair proteins. Lu X; Nguyen TA; Appella E; Donehower LA Cell Cycle; 2004 Nov; 3(11):1363-6. PubMed ID: 15539943 [TBL] [Abstract][Full Text] [Related]
19. Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites. Rossi M; Demidov ON; Anderson CW; Appella E; Mazur SJ Nucleic Acids Res; 2008 Dec; 36(22):7168-80. PubMed ID: 19015127 [TBL] [Abstract][Full Text] [Related]
20. TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist. Xu C; Liu H; Pirozzi CJ; Chen LH; Greer PK; Diplas BH; Zhang L; Waitkus MS; He Y; Yan H Acta Neuropathol Commun; 2021 Nov; 9(1):178. PubMed ID: 34732238 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]