These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
23. Binding and function of phosphotyrosines of the Ephrin A2 (EphA2) receptor using synthetic sterile α motif (SAM) domains. Borthakur S; Lee H; Kim S; Wang BC; Buck M J Biol Chem; 2014 Jul; 289(28):19694-703. PubMed ID: 24825902 [TBL] [Abstract][Full Text] [Related]
24. Solution structure of SHIP2 SH2 domain and its interaction with a phosphotyrosine peptide from c-MET. Wang Z; Nie Y; Zhang K; Xu H; Ramelot TA; Kennedy MA; Liu M; Zhu J; Yang Y Arch Biochem Biophys; 2018 Oct; 656():31-37. PubMed ID: 30165040 [TBL] [Abstract][Full Text] [Related]
25. Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights. Mercurio FA; Marasco D; Pirone L; Scognamiglio PL; Pedone EM; Pellecchia M; Leone M Chembiochem; 2013 Jan; 14(1):100-6. PubMed ID: 23239578 [TBL] [Abstract][Full Text] [Related]
26. The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics. Zhang Y; Wavreille AS; Kunys AR; Pei D Biochemistry; 2009 Nov; 48(46):11075-83. PubMed ID: 19839650 [TBL] [Abstract][Full Text] [Related]
27. Exploring the Ability of Cyclic Peptides to Target SAM Domains: A Computational and Experimental Study. Mercurio FA; Di Natale C; Pirone L; Vincenzi M; Marasco D; De Luca S; Pedone EM; Leone M Chembiochem; 2020 Mar; 21(5):702-711. PubMed ID: 31538690 [TBL] [Abstract][Full Text] [Related]
28. Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Lechtenberg BC; Gehring MP; Light TP; Horne CR; Matsumoto MW; Hristova K; Pasquale EB Nat Commun; 2021 Dec; 12(1):7047. PubMed ID: 34857764 [TBL] [Abstract][Full Text] [Related]
29. IQGAP2 Inhibits Migration and Invasion of Gastric Cancer Cells via Elevating SHIP2 Phosphatase Activity. Xu L; Shao Y; Ren L; Liu X; Li Y; Xu J; Ye Y Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32183047 [TBL] [Abstract][Full Text] [Related]
30. Dissociation of a Dynamic Protein Complex Studied by All-Atom Molecular Simulations. Zhang L; Borthakur S; Buck M Biophys J; 2016 Feb; 110(4):877-86. PubMed ID: 26910424 [TBL] [Abstract][Full Text] [Related]
31. Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention. Whitfield H; Hemmings AM; Mills SJ; Baker K; White G; Rushworth S; Riley AM; Potter BVL; Brearley CA J Med Chem; 2021 Apr; 64(7):3813-3826. PubMed ID: 33724834 [TBL] [Abstract][Full Text] [Related]
32. Modified Potential Functions Result in Enhanced Predictions of a Protein Complex by All-Atom Molecular Dynamics Simulations, Confirming a Stepwise Association Process for Native Protein-Protein Interactions. Li ZL; Buck M J Chem Theory Comput; 2019 Aug; 15(8):4318-4331. PubMed ID: 31241940 [TBL] [Abstract][Full Text] [Related]
33. SHIP2 multiple functions: a balance between a negative control of PtdIns(3,4,5)P₃ level, a positive control of PtdIns(3,4)P₂ production, and intrinsic docking properties. Erneux C; Edimo WE; Deneubourg L; Pirson I J Cell Biochem; 2011 Sep; 112(9):2203-9. PubMed ID: 21503961 [TBL] [Abstract][Full Text] [Related]
34. Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells. Fujii Y; Murata-Kamiya N; Hatakeyama M Cancer Sci; 2020 May; 111(5):1596-1606. PubMed ID: 32198795 [TBL] [Abstract][Full Text] [Related]
35. A role of the SAM domain in EphA2 receptor activation. Shi X; Hapiak V; Zheng J; Muller-Greven J; Bowman D; Lingerak R; Buck M; Wang BC; Smith AW Sci Rep; 2017 Mar; 7():45084. PubMed ID: 28338017 [TBL] [Abstract][Full Text] [Related]
36. The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner. Raaijmakers JH; Deneubourg L; Rehmann H; de Koning J; Zhang Z; Krugmann S; Erneux C; Bos JL Cell Signal; 2007 Jun; 19(6):1249-57. PubMed ID: 17314030 [TBL] [Abstract][Full Text] [Related]
38. Scaffold dependent role of the inositol 5'-phosphatase SHIP2, in regulation of oxidative stress induced apoptosis. Azzi A Arch Biochem Biophys; 2021 Jan; 697():108667. PubMed ID: 33181128 [TBL] [Abstract][Full Text] [Related]
39. Crosstalk of the EphA2 receptor with a serine/threonine phosphatase suppresses the Akt-mTORC1 pathway in cancer cells. Yang NY; Fernandez C; Richter M; Xiao Z; Valencia F; Tice DA; Pasquale EB Cell Signal; 2011 Jan; 23(1):201-12. PubMed ID: 20837138 [TBL] [Abstract][Full Text] [Related]