These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
252 related articles for article (PubMed ID: 39273169)
1. The GBA1 K198E Variant Is Associated with Suppression of Glucocerebrosidase Activity, Autophagy Impairment, Oxidative Stress, Mitochondrial Damage, and Apoptosis in Skin Fibroblasts. Perez-Abshana LP; Mendivil-Perez M; Jimenez-Del-Rio M; Velez-Pardo C Int J Mol Sci; 2024 Aug; 25(17):. PubMed ID: 39273169 [TBL] [Abstract][Full Text] [Related]
2. Rotenone Blocks the Glucocerebrosidase Enzyme and Induces the Accumulation of Lysosomes and Autophagolysosomes Independently of LRRK2 Kinase in HEK-293 Cells. Perez-Abshana LP; Mendivil-Perez M; Velez-Pardo C; Jimenez-Del-Rio M Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37445771 [TBL] [Abstract][Full Text] [Related]
3. Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. Albanese F; Mercatelli D; Finetti L; Lamonaca G; Pizzi S; Shimshek DR; Bernacchia G; Morari M Neurobiol Dis; 2021 Nov; 159():105487. PubMed ID: 34419621 [TBL] [Abstract][Full Text] [Related]
4. The relationship between glucocerebrosidase mutations and Parkinson disease. Migdalska-Richards A; Schapira AH J Neurochem; 2016 Oct; 139 Suppl 1(Suppl Suppl 1):77-90. PubMed ID: 26860875 [TBL] [Abstract][Full Text] [Related]
7. LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients. Ysselstein D; Nguyen M; Young TJ; Severino A; Schwake M; Merchant K; Krainc D Nat Commun; 2019 Dec; 10(1):5570. PubMed ID: 31804465 [TBL] [Abstract][Full Text] [Related]
8. Lysosomal Pathogenesis of Parkinson's Disease: Insights From LRRK2 and GBA1 Rodent Models. Volta M Neurotherapeutics; 2023 Jan; 20(1):127-139. PubMed ID: 36085537 [TBL] [Abstract][Full Text] [Related]
9. The lysosomal β-glucocerebrosidase strikes mitochondria: implications for Parkinson's therapeutics. Rubilar JC; Outeiro TF; Klein AD Brain; 2024 Aug; 147(8):2610-2620. PubMed ID: 38437875 [TBL] [Abstract][Full Text] [Related]
10. Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function. Kim MJ; Jeon S; Burbulla LF; Krainc D Hum Mol Genet; 2018 Jun; 27(11):1972-1988. PubMed ID: 29579237 [TBL] [Abstract][Full Text] [Related]
11. The Effect of p.G2019S Mutation in the Usenko TS; Timofeeva A; Beletskaia M; Basharova K; Baydakova G; Bezrukova A; Grunina M; Emelyanov A; Miliukhina I; Zakharova E; Pchelina S J Integr Neurosci; 2024 Jan; 23(1):16. PubMed ID: 38287861 [TBL] [Abstract][Full Text] [Related]
12. Acid ceramidase involved in pathogenic cascade leading to accumulation of α-synuclein in iPSC model of GBA1-associated Parkinson's disease. Kumar M; Srikanth MP; Deleidi M; Hallett PJ; Isacson O; Feldman RA Hum Mol Genet; 2023 May; 32(11):1888-1900. PubMed ID: 36752535 [TBL] [Abstract][Full Text] [Related]
13. Glucocerebrosidase 1 and leucine-rich repeat kinase 2 in Parkinson disease and interplay between the two genes. Lee CY; Menozzi E; Chau KY; Schapira AHV J Neurochem; 2021 Dec; 159(5):826-839. PubMed ID: 34618942 [TBL] [Abstract][Full Text] [Related]
14. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146 [TBL] [Abstract][Full Text] [Related]
15. Neuronopathic GBA1L444P Mutation Accelerates Glucosylsphingosine Levels and Formation of Hippocampal Alpha-Synuclein Inclusions. Mahoney-Crane CL; Viswanathan M; Russell D; Curtiss RAC; Freire J; Bobba SS; Coyle SD; Kandebo M; Yao L; Wan BL; Hatcher NG; Smith SM; Marcus JN; Volpicelli-Daley LA J Neurosci; 2023 Jan; 43(3):501-521. PubMed ID: 36639889 [TBL] [Abstract][Full Text] [Related]
16. Lysosomal functions and dysfunctions: Molecular and cellular mechanisms underlying Gaucher disease and its association with Parkinson disease. Horowitz M; Braunstein H; Zimran A; Revel-Vilk S; Goker-Alpan O Adv Drug Deliv Rev; 2022 Aug; 187():114402. PubMed ID: 35764179 [TBL] [Abstract][Full Text] [Related]
17. Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). Ho PW; Leung CT; Liu H; Pang SY; Lam CS; Xian J; Li L; Kung MH; Ramsden DB; Ho SL Autophagy; 2020 Feb; 16(2):347-370. PubMed ID: 30983487 [TBL] [Abstract][Full Text] [Related]
18. High Yield of Functional Dopamine-like Neurons Obtained in NeuroForsk 2.0 Medium to Study Acute and Chronic Rotenone Effects on Oxidative Stress, Autophagy, and Apoptosis. Quintero-Espinosa DA; Velez-Pardo C; Jimenez-Del-Rio M Int J Mol Sci; 2023 Oct; 24(21):. PubMed ID: 37958728 [TBL] [Abstract][Full Text] [Related]
19. Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis. Onal G; Yalçın-Çakmaklı G; Özçelik CE; Boussaad I; Şeker UÖŞ; Fernandes HJR; Demir H; Krüger R; Elibol B; Dökmeci S; Salman MM J Neurochem; 2024 Sep; 168(9):2543-2560. PubMed ID: 38641924 [TBL] [Abstract][Full Text] [Related]
20. Ambroxol-induced rescue of defective glucocerebrosidase is associated with increased LIMP-2 and saposin C levels in GBA1 mutant Parkinson's disease cells. Ambrosi G; Ghezzi C; Zangaglia R; Levandis G; Pacchetti C; Blandini F Neurobiol Dis; 2015 Oct; 82():235-242. PubMed ID: 26094596 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]