These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 39337533)

  • 1. Understanding the Role of the SMN Complex Component GEMIN5 and Its Functional Relationship with Demethylase KDM6B in the Flunarizine-Mediated Neuroprotection of Motor Neuron Disease Spinal Muscular Atrophy.
    Salman B; Bon E; Delers P; Cottin S; Pasho E; Ciura S; Sapaly D; Lefebvre S
    Int J Mol Sci; 2024 Sep; 25(18):. PubMed ID: 39337533
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
    Tseng YT; Chen CS; Jong YJ; Chang FR; Lo YC
    Pharmacol Res; 2016 Sep; 111():58-75. PubMed ID: 27241020
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SMN regulates GEMIN5 expression and acts as a modifier of GEMIN5-mediated neurodegeneration.
    Fortuna TR; Kour S; Chimata AV; Muiños-Bühl A; Anderson EN; Nelson Iv CH; Ward C; Chauhan O; O'Brien C; Rajasundaram D; Rajan DS; Wirth B; Singh A; Pandey UB
    Acta Neuropathol; 2023 Sep; 146(3):477-498. PubMed ID: 37369805
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy.
    Sapaly D; Dos Santos M; Delers P; Biondi O; Quérol G; Houdebine L; Khoobarry K; Girardet F; Burlet P; Armand AS; Chanoine C; Bureau JF; Charbonnier F; Lefebvre S
    Sci Rep; 2018 Feb; 8(1):2075. PubMed ID: 29391529
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice.
    Hsu YY; Jong YJ; Tsai HH; Tseng YT; An LM; Lo YC
    Br J Pharmacol; 2012 Jun; 166(3):1114-26. PubMed ID: 22220673
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The water extract of Liuwei dihuang possesses multi-protective properties on neurons and muscle tissue against deficiency of survival motor neuron protein.
    Tseng YT; Jong YJ; Liang WF; Chang FR; Lo YC
    Phytomedicine; 2017 Oct; 34():97-105. PubMed ID: 28899515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.
    Wang ZB; Zhang X; Li XJ
    Cell Res; 2013 Mar; 23(3):378-93. PubMed ID: 23208423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases.
    Sapaly D; Delers P; Coridon J; Salman B; Letourneur F; Dumont F; Lefebvre S
    Front Mol Biosci; 2020; 7():55. PubMed ID: 32363199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN Expression.
    Workman E; Kalda C; Patel A; Battle DJ
    J Biol Chem; 2015 Jun; 290(25):15662-15669. PubMed ID: 25911097
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
    Martinez TL; Kong L; Wang X; Osborne MA; Crowder ME; Van Meerbeke JP; Xu X; Davis C; Wooley J; Goldhamer DJ; Lutz CM; Rich MM; Sumner CJ
    J Neurosci; 2012 Jun; 32(25):8703-15. PubMed ID: 22723710
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α-XBP1 pathway.
    D'Amico D; Biondi O; Januel C; Bezier C; Sapaly D; Clerc Z; El Khoury M; Sundaram VK; Houdebine L; Josse T; Della Gaspera B; Martinat C; Massaad C; Weill L; Charbonnier F
    Neuropathol Appl Neurobiol; 2022 Aug; 48(5):e12816. PubMed ID: 35338505
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy.
    Ruggiu M; McGovern VL; Lotti F; Saieva L; Li DK; Kariya S; Monani UR; Burghes AH; Pellizzoni L
    Mol Cell Biol; 2012 Jan; 32(1):126-38. PubMed ID: 22037760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.
    Huo Q; Kayikci M; Odermatt P; Meyer K; Michels O; Saxena S; Ule J; Schümperli D
    RNA Biol; 2014; 11(11):1430-46. PubMed ID: 25692239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Decreased Motor Neuron Support by SMA Astrocytes due to Diminished MCP1 Secretion.
    Martin JE; Nguyen TT; Grunseich C; Nofziger JH; Lee PR; Fields D; Fischbeck KH; Foran E
    J Neurosci; 2017 May; 37(21):5309-5318. PubMed ID: 28450545
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models.
    Hua Y; Liu YH; Sahashi K; Rigo F; Bennett CF; Krainer AR
    Genes Dev; 2015 Feb; 29(3):288-97. PubMed ID: 25583329
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes.
    Rodriguez-Muela N; Parkhitko A; Grass T; Gibbs RM; Norabuena EM; Perrimon N; Singh R; Rubin LL
    J Clin Invest; 2018 Jul; 128(7):3008-3023. PubMed ID: 29672276
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered mRNA Splicing in SMN-Depleted Motor Neuron-Like Cells.
    Custer SK; Gilson TD; Li H; Todd AG; Astroski JW; Lin H; Liu Y; Androphy EJ
    PLoS One; 2016; 11(10):e0163954. PubMed ID: 27736905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models.
    Franco-Espin J; Gatius A; Armengol JÁ; Arumugam S; Moradi M; Sendtner M; Calderó J; Tabares L
    Biomolecules; 2022 Oct; 12(10):. PubMed ID: 36291733
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beta-lactam antibiotic offers neuroprotection in a spinal muscular atrophy model by multiple mechanisms.
    Nizzardo M; Nardini M; Ronchi D; Salani S; Donadoni C; Fortunato F; Colciago G; Falcone M; Simone C; Riboldi G; Govoni A; Bresolin N; Comi GP; Corti S
    Exp Neurol; 2011 Jun; 229(2):214-25. PubMed ID: 21295027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteomic assessment of a cell model of spinal muscular atrophy.
    Wu CY; Whye D; Glazewski L; Choe L; Kerr D; Lee KH; Mason RW; Wang W
    BMC Neurosci; 2011 Mar; 12():25. PubMed ID: 21385431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.