These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 39435659)

  • 1. Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy.
    Miralles RM; Boscia AR; Kittur S; Hanflink JC; Panchal PS; Yorek MS; Deutsch TCJ; Reever CM; Vundela SR; Wengert ER; Patel MK
    JCI Insight; 2024 Oct; 9(20):. PubMed ID: 39435659
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in
    Miralles RM; Boscia AR; Kittur S; Vundela SR; Wengert ER; Patel MK
    bioRxiv; 2024 Mar; ():. PubMed ID: 38464208
    [No Abstract]   [Full Text] [Related]  

  • 3. Somatostatin-Positive Interneurons Contribute to Seizures in
    Wengert ER; Miralles RM; Wedgwood KCA; Wagley PK; Strohm SM; Panchal PS; Idrissi AM; Wenker IC; Thompson JA; Gaykema RP; Patel MK
    J Neurosci; 2021 Nov; 41(44):9257-9273. PubMed ID: 34544834
    [No Abstract]   [Full Text] [Related]  

  • 4. Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of
    Ottolini M; Barker BS; Gaykema RP; Meisler MH; Patel MK
    J Neurosci; 2017 Aug; 37(32):7643-7655. PubMed ID: 28676574
    [No Abstract]   [Full Text] [Related]  

  • 5. Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy.
    Wagnon JL; Korn MJ; Parent R; Tarpey TA; Jones JM; Hammer MF; Murphy GG; Parent JM; Meisler MH
    Hum Mol Genet; 2015 Jan; 24(2):506-15. PubMed ID: 25227913
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NBI-921352, a first-in-class, Na
    Johnson JP; Focken T; Khakh K; Tari PK; Dube C; Goodchild SJ; Andrez JC; Bankar G; Bogucki D; Burford K; Chang E; Chowdhury S; Dean R; de Boer G; Decker S; Dehnhardt C; Feng M; Gong W; Grimwood M; Hasan A; Hussainkhel A; Jia Q; Lee S; Li J; Lin S; Lindgren A; Lofstrand V; Mezeyova J; Namdari R; Nelkenbrecher K; Shuart NG; Sojo L; Sun S; Taron M; Waldbrook M; Weeratunge D; Wesolowski S; Williams A; Wilson M; Xie Z; Yoo R; Young C; Zenova A; Zhang W; Cutts AJ; Sherrington RP; Pimstone SN; Winquist R; Cohen CJ; Empfield JR
    Elife; 2022 Mar; 11():. PubMed ID: 35234610
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy.
    Thompson JA; Miralles RM; Wengert ER; Wagley PK; Yu W; Wenker IC; Patel MK
    Epilepsia Open; 2022 Jun; 7(2):280-292. PubMed ID: 34826216
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.
    Makinson CD; Dutt K; Lin F; Papale LA; Shankar A; Barela AJ; Liu R; Goldin AL; Escayg A
    Exp Neurol; 2016 Jan; 275 Pt 1(0 1):46-58. PubMed ID: 26410685
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52.
    Hull JM; O'Malley HA; Chen C; Yuan Y; Denomme N; Bouza AA; Anumonwo C; Lopez-Santiago LF; Isom LL
    Ann Clin Transl Neurol; 2020 Nov; 7(11):2137-2149. PubMed ID: 32979291
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The contribution of Na
    Johnson JP; Focken T; Karimi Tari P; Dube C; Goodchild SJ; Andrez JC; Bankar G; Burford K; Chang E; Chowdhury S; Christabel J; Dean R; de Boer G; Dehnhardt C; Gong W; Grimwood M; Hussainkhel A; Jia Q; Khakh K; Lee S; Li J; Lin S; Lindgren A; Lofstrand V; Mezeyova J; Nelkenbrecher K; Shuart NG; Sojo L; Sun S; Waldbrook M; Wesolowski S; Wilson M; Xie Z; Zenova A; Zhang W; Scott FL; Cutts AJ; Sherrington RP; Winquist R; Cohen CJ; Empfield JR
    Br J Pharmacol; 2024 Oct; 181(20):3993-4011. PubMed ID: 38922847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.
    Baker EM; Thompson CH; Hawkins NA; Wagnon JL; Wengert ER; Patel MK; George AL; Meisler MH; Kearney JA
    Epilepsia; 2018 Jun; 59(6):1166-1176. PubMed ID: 29782051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons.
    Tidball AM; Lopez-Santiago LF; Yuan Y; Glenn TW; Margolis JL; Clayton Walker J; Kilbane EG; Miller CA; Martina Bebin E; Scott Perry M; Isom LL; Parent JM
    Brain; 2020 Oct; 143(10):3025-3040. PubMed ID: 32968789
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disrupting Epileptiform Activity by Preventing Parvalbumin Interneuron Depolarization Block.
    Călin A; Ilie AS; Akerman CJ
    J Neurosci; 2021 Nov; 41(45):9452-9465. PubMed ID: 34611025
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuronal hyperexcitability in a mouse model of
    Lopez-Santiago LF; Yuan Y; Wagnon JL; Hull JM; Frasier CR; O'Malley HA; Meisler MH; Isom LL
    Proc Natl Acad Sci U S A; 2017 Feb; 114(9):2383-2388. PubMed ID: 28193882
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome.
    Wengert ER; Wagley PK; Strohm SM; Reza N; Wenker IC; Gaykema RP; Christiansen A; Liau G; Patel MK
    Brain Res; 2022 Jan; 1775():147743. PubMed ID: 34843701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.
    Yu W; Hill SF; Xenakis JG; Pardo-Manuel de Villena F; Wagnon JL; Meisler MH
    Epilepsia; 2020 Dec; 61(12):2847-2856. PubMed ID: 33140451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SCN8A Epilepsy, Developmental Encephalopathy, and Related Disorders.
    Talwar D; Hammer MF
    Pediatr Neurol; 2021 Sep; 122():76-83. PubMed ID: 34353676
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phenotypic and genetic spectrum of SCN8A-related disorders, treatment options, and outcomes.
    Gardella E; Møller RS
    Epilepsia; 2019 Dec; 60 Suppl 3():S77-S85. PubMed ID: 31904124
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prax330 reduces persistent and resurgent sodium channel currents and neuronal hyperexcitability of subiculum neurons in a mouse model of SCN8A epileptic encephalopathy.
    Wengert ER; Saga AU; Panchal PS; Barker BS; Patel MK
    Neuropharmacology; 2019 Nov; 158():107699. PubMed ID: 31278928
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy.
    Quinn S; Zhang N; Fenton TA; Brusel M; Muruganandam P; Peleg Y; Giladi M; Haitin Y; Lerche H; Bassan H; Liu Y; Ben-Shalom R; Rubinstein M
    Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167127. PubMed ID: 38519006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.