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3. [Relationship between amitriptyline metabolism and polymorphic debrisoquine hydroxylation in native Chinese volunteers]. Zhang XH; Yu P; Gu NF; Yin JL; Jiang WD Yao Xue Xue Bao; 1993; 28(2):85-91. PubMed ID: 8328289 [TBL] [Abstract][Full Text] [Related]
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6. Amitriptyline pharmacokinetics and clinical response: II. Metabolic polymorphism assessed by hydroxylation of debrisoquine and mephenytoin. Baumann P; Jonzier-Perey M; Koeb L; Küpfer A; Tinguely D; Schöpf J Int Clin Psychopharmacol; 1986 Apr; 1(2):102-12. PubMed ID: 3571939 [TBL] [Abstract][Full Text] [Related]
7. Demethylation and hydroxylation of amitriptyline, nortriptyline, and 10-hydroxyamitriptyline in human liver microsomes. Mellström B; von Bahr C Drug Metab Dispos; 1981; 9(6):565-8. PubMed ID: 6120818 [TBL] [Abstract][Full Text] [Related]
8. Slow hydroxylation of tricyclic antidepressants--relationship to polymorphic drug oxidation. Sjöqvist F; Bertilsson L Prog Clin Biol Res; 1986; 214():169-88. PubMed ID: 3523507 [TBL] [Abstract][Full Text] [Related]
9. Regioselectivity and substrate concentration-dependency of involvement of the CYP2D subfamily in oxidative metabolism of amitriptyline and nortriptyline in rat liver microsomes. Masubuchi Y; Iwasa T; Fujita S; Suzuki T; Horie T; Narimatsu S J Pharm Pharmacol; 1996 Sep; 48(9):925-9. PubMed ID: 9036183 [TBL] [Abstract][Full Text] [Related]
10. Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test. Laine K; Tybring G; Härtter S; Andersson K; Svensson JO; Widén J; Bertilsson L Clin Pharmacol Ther; 2001 Oct; 70(4):327-35. PubMed ID: 11673748 [TBL] [Abstract][Full Text] [Related]
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16. Inhibition of debrisoquin clearance in perfused rat livers and inhibition of dextromethorphan metabolism in human liver microsomes by 4-hydroxydebrisoquin or other metabolites of debrisoquin. Jaruratanasirikul S; Cooper AD; Blaschke TF Drug Metab Dispos; 1992; 20(3):379-82. PubMed ID: 1355711 [TBL] [Abstract][Full Text] [Related]
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19. Phenotypic consistency in hydroxylation of desmethylimipramine and debrisoquine in healthy subjects and in human liver microsomes. Spina E; Birgersson C; von Bahr C; Ericsson O; Mellström B; Steiner E; Sjöqvist F Clin Pharmacol Ther; 1984 Nov; 36(5):677-82. PubMed ID: 6488689 [TBL] [Abstract][Full Text] [Related]
20. 10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes. Dalén P; Dahl ML; Bernal Ruiz ML; Nordin J; Bertilsson L Clin Pharmacol Ther; 1998 Apr; 63(4):444-52. PubMed ID: 9585799 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]