BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

78 related articles for article (PubMed ID: 3972726)

  • 1. Vanoxonin, a new inhibitor of thymidylate synthetase. II. Structure determination and total synthesis.
    Kanai F; Isshiki K; Umezawa Y; Morishima H; Naganawa H; Takita T; Takeuchi T; Umezawa H
    J Antibiot (Tokyo); 1985 Jan; 38(1):31-8. PubMed ID: 3972726
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vanoxonin, a new inhibitor of thymidylate synthetase. III. Inhibition of thymidylate synthetase by vanoxonin-vanadium complex.
    Kanai F; Kaneko T; Morishima H; Isshiki K; Takita T; Takeuchi T; Umezawa H
    J Antibiot (Tokyo); 1985 Jan; 38(1):39-50. PubMed ID: 3972727
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vanoxonin, a new inhibitor of thymidylate synthetase.
    Kanai F; Sawa T; Hamada M; Naganawa H; Takeuchi T; Umezawa H
    J Antibiot (Tokyo); 1983 Jun; 36(6):656-60. PubMed ID: 6874588
    [TBL] [Abstract][Full Text] [Related]  

  • 4. trans-5-(3,3,3-Trifluoro-1-propenyl-)-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase.
    Wataya Y; Matsuda A; Santi DV; Bergstrom DE; Ruth JL
    J Med Chem; 1979 Apr; 22(4):339-40. PubMed ID: 430474
    [No Abstract]   [Full Text] [Related]  

  • 5. Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-(( 2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino) benzoyl)-L-glutamic acid (CB3717), on human lymphoblastoid cells.
    Jackson RC; Jackman AL; Calvert AH
    Biochem Pharmacol; 1983 Dec; 32(24):3783-90. PubMed ID: 6661252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A potent multisubstrate analogue inhibitor of human thymidylate synthetase.
    Srinivasan A; Amarnath V; Broom AD; Zou FC; Cheng YC
    J Med Chem; 1984 Dec; 27(12):1710-7. PubMed ID: 6502602
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quinazoline antifolate thymidylate synthase inhibitors: gamma-linked L-D, D-D, and D-L dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Bavetsias V; Jackman AL; Kimbell R; Gibson W; Boyle FT; Bisset GM
    J Med Chem; 1996 Jan; 39(1):73-85. PubMed ID: 8568829
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Folate-based inhibitors of thymidylate synthase: synthesis and antitumor activity of gamma-linked sterically hindered dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Bavetsias V; Jackman AL; Marriott JH; Kimbell R; Gibson W; Boyle FT; Bisset GM
    J Med Chem; 1997 May; 40(10):1495-510. PubMed ID: 9154971
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of thymidylate synthetase of the human lymphocytes.
    Haurani FI
    Cancer Biochem Biophys; 1979; 4(2):75-7. PubMed ID: 317899
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human thymidylate synthetase--III. Effects of methotrexate and folate analogs.
    Szeto DW; Cheng YC; Rosowsky A; Yu CS; Modest EJ; Piper JR; Temple C; Elliott RD; Rose JD; Montgomery JA
    Biochem Pharmacol; 1979 Sep; 28(17):2633-7. PubMed ID: 518674
    [No Abstract]   [Full Text] [Related]  

  • 11. The synthesis and thymidylate synthase inhibitory activity of L-gamma-L-linked dipeptide and L-gamma-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Bisset GM; Bavetsias V; Thornton TJ; Pawelczak K; Calvert AH; Hughes LR; Jackman AL
    J Med Chem; 1994 Sep; 37(20):3294-302. PubMed ID: 7932557
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Plasma nucleoside and base levels following treatment with the new thymidylate synthetase inhibitor CB 3717.
    Taylor GA; Jackman AL; Calvert AH; Harrap KR
    Adv Exp Med Biol; 1984; 165 Pt B():379-82. PubMed ID: 6720435
    [No Abstract]   [Full Text] [Related]  

  • 13. Thymidylate synthetase-positive and -negative murine mammary FM3A carcinoma cells as a useful system for detecting thymidylate synthetase inhibitors.
    Balzarini J; de Clercq E; Ayusawa D; Seno T
    FEBS Lett; 1984 Jul; 173(1):227-32. PubMed ID: 6745430
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5(E)-(3-azidostyryl)-2'-deoxyuridine 5'-phosphate is a photoactivated inhibitor of thymidylate synthetase.
    De Clercq E; Balzarini J; Chang CT; Bigge CF; Kalaritis P; Mertes MP
    Biochem Biophys Res Commun; 1980 Dec; 97(3):1068-75. PubMed ID: 7470133
    [No Abstract]   [Full Text] [Related]  

  • 15. Inhibition of thymidylate synthetase by the new quinazoline antifolate, CB 3717; enzyme purification and kinetics.
    Jackman AL; Calvert AH; Hart LI; Harrap KR
    Adv Exp Med Biol; 1984; 165 Pt B():375-8. PubMed ID: 6720434
    [No Abstract]   [Full Text] [Related]  

  • 16. 5-Ethyl-2'-deoxyuridine-5'-monophosphate inhibition of the thymidylate synthetase from Escherichia coli.
    Walter RD; Gauri KK
    Biochem Pharmacol; 1975 May; 24(9):1025-7. PubMed ID: 1098667
    [No Abstract]   [Full Text] [Related]  

  • 17. Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.
    Santi DV
    J Med Chem; 1980 Feb; 23(2):103-11. PubMed ID: 6987403
    [No Abstract]   [Full Text] [Related]  

  • 18. Enhancement by thymidine of 5-fluorouracil's inhibition of thymidylate synthetase in human tumors.
    Wolberg WH
    Cancer Treat Rep; 1979; 63(11-12):1817-20. PubMed ID: 526916
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytotoxicity of 5-nitro-2'-deoxyuridine by in vivo inhibition of thymidylate synthetase.
    Washtien W; Matsuda A; Wataya Y; Santi DV
    Biochem Pharmacol; 1978; 27(22):2663-6. PubMed ID: 215163
    [No Abstract]   [Full Text] [Related]  

  • 20. Thymidylate synthase inhibition in cells with arrested DNA synthesis is not due to an allosteric interaction in the replitase complex.
    Rode W; Jastreboff MM; Bertino JR
    Biochem Biophys Res Commun; 1985 Apr; 128(1):345-51. PubMed ID: 3921023
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.