168 related articles for article (PubMed ID: 3990443)
1. Incorporation of 5-substituted pyrimidine nucleoside analogues into DNA of a thymidylate synthetase-deficient murine FM3A carcinoma cell line.
Balzarini J; De Clercq E; Ayusawa D; Seno T
Methods Find Exp Clin Pharmacol; 1985 Jan; 7(1):19-28. PubMed ID: 3990443
[TBL] [Abstract][Full Text] [Related]
2. Thymidylate synthetase-deficient mouse FM3A mammary carcinoma cell line as a tool for studying the thymidine salvage pathway and the incorporation of thymidine analogues into host cell DNA.
Balzarini J; De Clercq E; Ayusawa D; Seno T
Biochem J; 1984 Jan; 217(1):245-52. PubMed ID: 6696722
[TBL] [Abstract][Full Text] [Related]
3. Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.
Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Shimizu K; Seno T
Mol Pharmacol; 1987 Sep; 32(3):410-6. PubMed ID: 2823092
[TBL] [Abstract][Full Text] [Related]
4. Highly selective cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine derivatives for murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 thymidine kinase gene.
Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Seno T
Mol Pharmacol; 1985 Dec; 28(6):581-7. PubMed ID: 3001499
[TBL] [Abstract][Full Text] [Related]
5. Differential affinities of pyrimidine nucleoside analogues for deoxythymidine and deoxycytidine kinase determine their incorporation into murine leukemia L1210 cells.
Balzarini J; De Clercq E
Acta Biochim Pol; 1987; 34(2):63-77. PubMed ID: 2823514
[TBL] [Abstract][Full Text] [Related]
6. Role of deoxycytidine kinase in the inhibitory activity of 5-substituted 2'-deoxycytidines and cytosine arabinosides on tumor cell growth.
Balzarini J; De Clercq E
Mol Pharmacol; 1983 Jan; 23(1):175-81. PubMed ID: 6306422
[TBL] [Abstract][Full Text] [Related]
7. Mechanism of cytostatic action of novel 5-(thien-2-yl)- and 5-(furan-2-yl)-substituted pyrimidine nucleoside analogues against tumor cells transfected by the thymidine kinase gene of herpes simplex virus.
Bohman C; Balzarini J; Wigerinck P; Van Aerschot A; Herdewijn P; De Clercq E
J Biol Chem; 1994 Mar; 269(11):8036-43. PubMed ID: 8132526
[TBL] [Abstract][Full Text] [Related]
8. Thymidylate synthetase-positive and -negative murine mammary FM3A carcinoma cells as a useful system for detecting thymidylate synthetase inhibitors.
Balzarini J; de Clercq E; Ayusawa D; Seno T
FEBS Lett; 1984 Jul; 173(1):227-32. PubMed ID: 6745430
[TBL] [Abstract][Full Text] [Related]
9. Antiviral, antimetabolic, and cytotoxic activities of 5-substituted 2'-deoxycytidines.
De Clercq E; Balzarini J; Descamps J; Huang GF; Torrence PF; Bergstrom DE; Jones AS; Serafinowski P; Verhelst G; Walker RT
Mol Pharmacol; 1982 Jan; 21(1):217-23. PubMed ID: 7132959
[TBL] [Abstract][Full Text] [Related]
10. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
Balzarini J; De Clercq E; Verbruggen A; Crumpacker C; Ayusawa D; Seno T
Anticancer Res; 1986; 6(5):1077-84. PubMed ID: 2432829
[TBL] [Abstract][Full Text] [Related]
11. Metabolic competition studies of 2'-fluoro-5-iodo-1-beta-d-arabinofuranosylcytosine in vero cells and herpes simplex type 1-infected vero cells.
Chou TC; Lopez C; Colacino JM; Feinberg A; Watanabe KA; Fox JJ; Philips FS
Mol Pharmacol; 1984 Nov; 26(3):587-93. PubMed ID: 6092904
[TBL] [Abstract][Full Text] [Related]
12. Regulation of thymidine kinase and thymidylate synthase in intact human lymphoblast CCRF-CEM cells.
Xu YZ; Plunkett W
J Biol Chem; 1993 Oct; 268(30):22363-8. PubMed ID: 8226747
[TBL] [Abstract][Full Text] [Related]
13. 2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis.
Balzarini J; Cooney DA; Dalal M; Kang GJ; Cupp JE; DeClercq E; Broder S; Johns DG
Mol Pharmacol; 1987 Dec; 32(6):798-806. PubMed ID: 2826994
[TBL] [Abstract][Full Text] [Related]
14. Use of 5-trifluoromethyldeoxycytidine and tetrahydrouridine to circumvent catabolism and exploit high levels of cytidine deaminase in tumors to achieve DNA- and target-directed therapies.
Mekras JA; Boothman DA; Greer SB
Cancer Res; 1985 Nov; 45(11 Pt 1):5270-80. PubMed ID: 2932216
[TBL] [Abstract][Full Text] [Related]
15. Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies.
Mekras JA; Boothman DA; Perez LM; Greer S
Cancer Res; 1984 Jun; 44(6):2551-60. PubMed ID: 6539164
[TBL] [Abstract][Full Text] [Related]
16. Role of thymidylate synthetase in the cytostatic activity of pyrimidine nucleoside analogues.
Balzarini J
Bull Mem Acad R Med Belg; 1985; 140(11):432-40. PubMed ID: 3841831
[No Abstract] [Full Text] [Related]
17. Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro.
Yalowich JC; Kalman TI
Biochem Pharmacol; 1985 Jul; 34(13):2319-24. PubMed ID: 3160352
[TBL] [Abstract][Full Text] [Related]
18. Selective inhibition of the proliferation of herpes simplex virus type 1 thymidine kinase gene-transformed murine mammary FM3A carcinoma cells by (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
Balzarini J; De Clercq E; Ayusawa D; Shimizu K; Seno T
Nucleic Acids Symp Ser; 1985; (16):283-6. PubMed ID: 3003708
[TBL] [Abstract][Full Text] [Related]
19. Metabolism of pyrimidine bases and nucleosides in Bacillus subtilis.
Rima BK; Takahashi I
J Bacteriol; 1977 Feb; 129(2):574-9. PubMed ID: 402352
[TBL] [Abstract][Full Text] [Related]
20. Effects of deoxynucleosides on cultured human leukemia cell growth and deoxynucleotide pools.
Ross DD; Akman SA; Schrecker AW; Bachur NR
Cancer Res; 1981 Nov; 41(11 Pt 1):4493-8. PubMed ID: 6975653
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
