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5. Monacolin M, a new inhibitor of cholesterol biosynthesis. Endo A; Komagata D; Shimada H J Antibiot (Tokyo); 1986 Dec; 39(12):1670-3. PubMed ID: 3818440 [TBL] [Abstract][Full Text] [Related]
6. Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase. Matsuoka T; Miyakoshi S; Tanzawa K; Nakahara K; Hosobuchi M; Serizawa N Eur J Biochem; 1989 Oct; 184(3):707-13. PubMed ID: 2509201 [TBL] [Abstract][Full Text] [Related]
7. Formation of dihydroxy derivative of ML-236B from ML-236B (compactin) by lipid peroxidation. Serizawa N; Nakahara K; Matsuoka T J Antibiot (Tokyo); 1990 Aug; 43(8):1031-3. PubMed ID: 2120167 [No Abstract] [Full Text] [Related]
8. Biochemical aspect of HMG CoA reductase inhibitors. Endo A; Hasumi K Adv Enzyme Regul; 1989; 28():53-64. PubMed ID: 2696346 [TBL] [Abstract][Full Text] [Related]
9. Biosynthesis of ML-236B (compactin) and monacolin K. Endo A; Negishi Y; Iwashita T; Mizukawa K; Hirama M J Antibiot (Tokyo); 1985 Mar; 38(3):444-8. PubMed ID: 4008338 [No Abstract] [Full Text] [Related]
10. Biosynthesis of monacolins: conversion of monacolin J to monacolin K (mevinolin). Kimura K; Komagata D; Murakawa S; Endo A J Antibiot (Tokyo); 1990 Dec; 43(12):1621-2. PubMed ID: 2276983 [No Abstract] [Full Text] [Related]
11. Dihydromonacolin L and monacolin X, new metabolites which inhibit cholesterol biosynthesis. Endo A; Hasumi K; Nakamura T; Kunishima M; Masuda M J Antibiot (Tokyo); 1985 Mar; 38(3):321-7. PubMed ID: 3839224 [TBL] [Abstract][Full Text] [Related]
12. Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase. Endo A J Med Chem; 1985 Apr; 28(4):401-5. PubMed ID: 3981532 [No Abstract] [Full Text] [Related]
14. Monacolin K, a new hypocholesterolemic agent that specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase. Endo A J Antibiot (Tokyo); 1980 Mar; 33(3):334-6. PubMed ID: 7380744 [No Abstract] [Full Text] [Related]
15. Microbial hydroxylation of ML-236B (compactin). Studies on microorganisms capable of 3 beta-hydroxylation of ML-236B. Serizawa N; Serizawa S; Nakagawa K; Furuya K; Okazaki T; Terahara A J Antibiot (Tokyo); 1983 Jul; 36(7):887-91. PubMed ID: 6684108 [TBL] [Abstract][Full Text] [Related]
16. A possible translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase induction by ML-236b(compactin) in isolated rat hepatocytes. Koizumi J; Mabuchi H; Takeda R; Okamoto H Biochem Biophys Res Commun; 1982 Sep; 108(1):240-6. PubMed ID: 7150285 [No Abstract] [Full Text] [Related]
17. Effects of ML-236b (compactin) on sterol synthesis and low density lipoprotein receptor activities in fibroblasts of patients with homozygous familial hypercholesterolemia. Haba T; Mabuchi H; Yoshimura A; Watanabe A; Wakasugi T; Tatami R; Ueda K; Ueda R; Kametani T; Koizumi J; Miyamoto S; Takeda R; Takeshita H J Clin Invest; 1981 May; 67(5):1532-40. PubMed ID: 7229037 [TBL] [Abstract][Full Text] [Related]
18. Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Alberts AW; Chen J; Kuron G; Hunt V; Huff J; Hoffman C; Rothrock J; Lopez M; Joshua H; Harris E; Patchett A; Monaghan R; Currie S; Stapley E; Albers-Schonberg G; Hensens O; Hirshfield J; Hoogsteen K; Liesch J; Springer J Proc Natl Acad Sci U S A; 1980 Jul; 77(7):3957-61. PubMed ID: 6933445 [TBL] [Abstract][Full Text] [Related]
19. Overaccumulation of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase in a compactin(ML-236B)-resistant mouse cell line with defects in the regulation of its activity. Hasumi K; Yamada A; Shimizu Y; Endo A Eur J Biochem; 1987 May; 164(3):547-52. PubMed ID: 3569277 [TBL] [Abstract][Full Text] [Related]
20. Taxonomy of actinomycetes capable of hydroxylation of ML-236B (compactin). Okazaki T; Serizawa N; Enokita R; Torikata A; Terahara A J Antibiot (Tokyo); 1983 Sep; 36(9):1176-83. PubMed ID: 6630076 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]