BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 4087135)

  • 1. Prediction of the plasma concentration time courses of various drugs in humans based on data from rats.
    Sawada Y; Harashima H; Hanano M; Sugiyama Y; Iga T
    J Pharmacobiodyn; 1985 Sep; 8(9):757-66. PubMed ID: 4087135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of serum concentration time course of quinidine in human using a physiologically based pharmacokinetic model developed from the rat.
    Harashima H; Sawada Y; Sugiyama Y; Iga T; Hanano M
    J Pharmacobiodyn; 1986 Feb; 9(2):132-8. PubMed ID: 3712213
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
    Sawada Y; Hanano M; Sugiyama Y; Iga T
    J Pharmacokinet Biopharm; 1985 Oct; 13(5):477-92. PubMed ID: 3938813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Correlation of unbound plasma clearances of fifteen extensively metabolized drugs between humans and rats.
    Chiou WL; Hsu FH
    Pharm Res; 1988 Oct; 5(10):668-72. PubMed ID: 3244621
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Physiologically based pharmacokinetics of drug-drug interaction: a study of tolbutamide-sulfonamide interaction in rats.
    Sugita O; Sawada Y; Sugiyama Y; Iga T; Hanano M
    J Pharmacokinet Biopharm; 1982 Jun; 10(3):297-316. PubMed ID: 7175701
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data.
    Nakayama K; Kamimura H; Suemizu H; Yoneda N; Nishiwaki M; Iwamoto K; Mizunaga M; Negoro T; Ito S; Yamazaki H; Nomura Y
    Drug Metab Pharmacokinet; 2020 Aug; 35(4):389-396. PubMed ID: 32690433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of diazepam on the biliary excretion of diphenylhydantoin in the rat.
    El-Hawari AM; Plaa GL
    J Pharmacol Exp Ther; 1977 Apr; 201(1):14-25. PubMed ID: 850136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Use of unbound volumes of drug distribution in pharmacokinetic calculations.
    Stepensky D
    Eur J Pharm Sci; 2011 Jan; 42(1-2):91-8. PubMed ID: 21050885
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of changes in the clinical pharmacokinetics of basic drugs on the basis of octanol-water partition coefficients.
    Ishizaki J; Yokogawa K; Nakashima E; Ichimura F
    J Pharm Pharmacol; 1997 Aug; 49(8):762-7. PubMed ID: 9379352
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic analysis of phenytoin disposition in rats with experimental renal and hepatic diseases.
    Itoh T; Sawada Y; Lin TH; Iga T; Hanano M
    J Pharmacobiodyn; 1988 May; 11(5):289-308. PubMed ID: 3171873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.
    Uchida Y; Ohtsuki S; Kamiie J; Terasaki T
    J Pharmacol Exp Ther; 2011 Nov; 339(2):579-88. PubMed ID: 21828264
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding.
    Ye M; Nagar S; Korzekwa K
    Biopharm Drug Dispos; 2016 Apr; 37(3):123-41. PubMed ID: 26531057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative physiologically based pharmacokinetics of hexobarbital, phenobarbital and thiopental in the rat.
    Igari Y; Sugiyama Y; Awazu S; Hanano M
    J Pharmacokinet Biopharm; 1982 Feb; 10(1):53-75. PubMed ID: 7069578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of phenytoin and phenobarbital on the disposition of a single oral dose of clonazepam.
    Khoo KC; Mendels J; Rothbart M; Garland WA; Colburn WA; Min BH; Lucek R; Carbone JJ; Boxenbaum HG; Kaplan SA
    Clin Pharmacol Ther; 1980 Sep; 28(3):368-75. PubMed ID: 7408397
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of diazepam disposition in the rat and man by a physiologically based pharmacokinetic model.
    Igari Y; Sugiyama Y; Sawada Y; Iga T; Hanano M
    J Pharmacokinet Biopharm; 1983 Dec; 11(6):577-93. PubMed ID: 6678311
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of nonlinear tissue distribution of quinidine in rats by physiologically based pharmacokinetics.
    Harashima H; Sawada Y; Sugiyama Y; Iga T; Hanano M
    J Pharmacokinet Biopharm; 1985 Aug; 13(4):425-40. PubMed ID: 4087170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct determination of the ratio of unbound fraction in plasma to unbound fraction in microsomal system (fu p/fu mic) for refined prediction of phase I mediated metabolic hepatic clearance.
    Deshmukh SV; Harsch A
    J Pharmacol Toxicol Methods; 2011; 63(1):35-9. PubMed ID: 20433934
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Improved Human Pharmacokinetic Prediction of Hepatically Metabolized Drugs With Species-Specific Systemic Clearance.
    Horiuchi K; Ohnishi S; Matsuzaki T; Funaki S; Watanabe A; Mizutare T; Matsumoto S; Nezasa KI; Hasegawa H
    J Pharm Sci; 2018 May; 107(5):1443-1453. PubMed ID: 29331382
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prediction of the volumes of distribution of basic drugs in humans based on data from animals.
    Sawada Y; Hanano M; Sugiyama Y; Harashima H; Iga T
    J Pharmacokinet Biopharm; 1984 Dec; 12(6):587-96. PubMed ID: 6533294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative investigation of the brain-to-cerebrospinal fluid unbound drug concentration ratio under steady-state conditions in rats using a pharmacokinetic model and scaling factors for active efflux transporters.
    Kodaira H; Kusuhara H; Fuse E; Ushiki J; Sugiyama Y
    Drug Metab Dispos; 2014 Jun; 42(6):983-9. PubMed ID: 24644297
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.