These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 4432244)

  • 1. Increased antitumor activity of cyclophosphamide (Endoxan) following pretreatment with inducer of drug-metabolizing enzymes (cytochrome P-450).
    Oira S; Maezawa S; Irinoda Y; Watanabe K; Kitada K
    Tohoku J Exp Med; 1974 Sep; 114(1):55-60. PubMed ID: 4432244
    [No Abstract]   [Full Text] [Related]  

  • 2. Effects of inducer of liver drug-metabolizing enzyme on blood level of active metabolites of cyclophosphamide in rats and in cancer patients.
    Maezawa S; Ohira S; Sakuma M; Matsuoka S; Wakui A; Saito T
    Tohoku J Exp Med; 1981 May; 134(1):45-53. PubMed ID: 7314093
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduction in hepatic microsomal cytochromes P-450 and b5 in rats exposed to 1,2-dibromo-3-chloropropane and carbon tetrachloride: enhancement of effect by pretreatment with phenobarbital.
    Moody DE; Head B; Smuckler EA
    J Environ Pathol Toxicol; 1979 Dec; 3(1-2):177-90. PubMed ID: 121136
    [No Abstract]   [Full Text] [Related]  

  • 4. Modification of the mutagenicity and teratogenicity of cyclophosphamide in rats with inducers of the cytochromes P-450.
    Hales BF
    Teratology; 1981 Aug; 24(1):1-11. PubMed ID: 7029774
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly purified cytochrome P-448 and P=450 from rat liver microsomes.
    Ryan D; Lu YH; Kawalek J; West SB; Levin L
    Biochem Biophys Res Commun; 1975 Jun; 64(4):1134-41. PubMed ID: 1137591
    [No Abstract]   [Full Text] [Related]  

  • 6. Induction by phenobarbital of hepatic microsomal drug-metabolizing enzyme system in partially hepatectomized rats.
    Hino Y; Imai Y; Sato R
    J Biochem; 1974 Oct; 76(4):735-44. PubMed ID: 4436286
    [No Abstract]   [Full Text] [Related]  

  • 7. Studies on the mechanism of denaturation of cytochrome P-450 by cyclophosphamide and its metabolites.
    Gurtoo HL; Marinello AJ; Struck RF; Paul B; Dahms RP
    J Biol Chem; 1981 Nov; 256(22):11691-701. PubMed ID: 7298626
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450.
    Yu L; Waxman DJ
    Drug Metab Dispos; 1996 Nov; 24(11):1254-62. PubMed ID: 8937861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ethoxyquin as an inducer and inhibitor of phenobarbital-type cytochrome P-450 in rat liver microsomes.
    Kahl R; Netter KJ
    Toxicol Appl Pharmacol; 1977 Jun; 40(3):473-83. PubMed ID: 882982
    [No Abstract]   [Full Text] [Related]  

  • 10. Metabolism of cyclophosphamide by purified cytochrome P-450 from microsomes of phenobarbital-treated rats.
    Struck RF; Kari P; Kalin J; Montgomery JA; Marinello AJ; Love J; Bansal SK; Gurtoo HL
    Biochem Biophys Res Commun; 1984 Apr; 120(2):390-6. PubMed ID: 6732764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity.
    Yu LJ; Drewes P; Gustafsson K; Brain EG; Hecht JE; Waxman DJ
    J Pharmacol Exp Ther; 1999 Mar; 288(3):928-37. PubMed ID: 10027828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450IIIA (steroid-inducible) gene subfamily.
    Ciaccio PJ; Halpert JR
    Arch Biochem Biophys; 1989 Jun; 271(2):284-99. PubMed ID: 2786372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of muroctasin on the activities of drug metabolizing enzymes in liver microsomes of rats.
    Kamataki T; Komori M; Iwasaki M; Ohi H; Kitada M; Miura T; Ono K
    Arzneimittelforschung; 1988 Jul; 38(7A):1019-22. PubMed ID: 3263867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of protein-calorie malnutrition on drug metabolism in rat liver microsomes.
    Anthony LE
    J Nutr; 1973 Jun; 103(6):811-20. PubMed ID: 4196150
    [No Abstract]   [Full Text] [Related]  

  • 15. Effects of phenobarbital and beta-naphthoflavone on the activation of cyclophosphamide to mutagenic metabolites in vitro by liver and kidney from male and female rats.
    Hales BF; Jain R
    Biochem Pharmacol; 1980 Jul; 29(14):2031-7. PubMed ID: 6996685
    [No Abstract]   [Full Text] [Related]  

  • 16. Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes.
    Weber GF; Waxman DJ
    Biochem Pharmacol; 1993 Apr; 45(8):1685-94. PubMed ID: 8484807
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of oxygenated cytochrome P-450 and of cytochrome b5 in hepatic microsomal drug oxidations.
    Baron J; Hildebrandt AG; Peterson JA; Estabrook RW
    Drug Metab Dispos; 1973; 1(1):129-38. PubMed ID: 4149374
    [No Abstract]   [Full Text] [Related]  

  • 18. Complexes of cytochrome P450 with metyrapone. A convenient method for the quantitative analysis of phenobarbital-inducible cytochrome P450 in rat liver microsomes.
    Mitani F; Shephard EA; Phillips IR; Rabin BR
    FEBS Lett; 1982 Nov; 148(2):302-6. PubMed ID: 7152025
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of drugs and chemical upon hepatic enzymes and proteins-I. Structure-activity relationship between various barbiturates and microsomal enzyme induction in rat liver.
    Adachi Y; Yamamoto T
    Biochem Pharmacol; 1976 Mar; 25(6):663-8. PubMed ID: 6036
    [No Abstract]   [Full Text] [Related]  

  • 20. Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
    Serino F; Grevel J; Napoli KL; Kahan BD; Strobel HW
    Transplant Proc; 1994 Oct; 26(5):2916-7. PubMed ID: 7940922
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 6.