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1. The neurochemistry of Parkinson's disease: effect of L-dopa therapy. Lloyd KG; Davidson L; Hornykiewicz O J Pharmacol Exp Ther; 1975 Dec; 195(3):453-64. PubMed ID: 489 [TBL] [Abstract][Full Text] [Related]
2. Coadministration of β-asarone and levodopa increases dopamine in rat brain by accelerating transformation of levodopa: a different mechanism from Madopar. Huang L; Deng M; Zhang S; Fang Y; Li L Clin Exp Pharmacol Physiol; 2014 Sep; 41(9):685-90. PubMed ID: 24910244 [TBL] [Abstract][Full Text] [Related]
3. BIA 3-202, a novel catechol-O-methyltransferase inhibitor, enhances the availability of L-DOPA to the brain and reduces its O-methylation. Parada A; Loureiro AI; Vieira-Coelho MA; Hainzl D; Soares-da-Silva P Eur J Pharmacol; 2001 May; 420(1):27-32. PubMed ID: 11412836 [TBL] [Abstract][Full Text] [Related]
4. Parkinson's disease: from brain homogenate to treatment. Hornykiewicz O Fed Proc; 1973 Feb; 32(2):183-90. PubMed ID: 4143953 [No Abstract] [Full Text] [Related]
6. Effects of acute and sub-chronic L-dopa therapy on striatal L-dopa methylation and dopamine oxidation in an MPTP mouse model of Parkinsons disease. Smith ML; King J; Dent L; Mackey V; Muthian G; Griffin B; Charlton CG Life Sci; 2014 Aug; 110(1):1-7. PubMed ID: 24880075 [TBL] [Abstract][Full Text] [Related]
7. L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease. King JM; Muthian G; Mackey V; Smith M; Charlton C Life Sci; 2011 Oct; 89(17-18):638-43. PubMed ID: 21871902 [TBL] [Abstract][Full Text] [Related]
8. Effects of 3-O-methyldopa, L-3,4-dihydroxyphenylalanine metabolite, on locomotor activity and dopamine turnover in rats. Onzawa Y; Kimura Y; Uzuhashi K; Shirasuna M; Hirosawa T; Taogoshi T; Kihira K Biol Pharm Bull; 2012; 35(8):1244-8. PubMed ID: 22863920 [TBL] [Abstract][Full Text] [Related]
9. Peripheral and central inhibitors of catechol-O-methyl transferase: effects on liver and brain COMT activity and L-DOPA metabolism. Brannan T; Prikhojan A; Yahr MD J Neural Transm (Vienna); 1997; 104(1):77-87. PubMed ID: 9085195 [TBL] [Abstract][Full Text] [Related]
10. Simultaneous MAO-B and COMT inhibition in L-Dopa-treated patients with Parkinson's disease. Lyytinen J; Kaakkola S; Ahtila S; Tuomainen P; Teräväinen H Mov Disord; 1997 Jul; 12(4):497-505. PubMed ID: 9251066 [TBL] [Abstract][Full Text] [Related]
11. Serotonergic neurones are not involved in action of L-dopa in Parkinson's disease. Melamed E; Hefti F; Liebman J; Schlosberg AJ; Wurtman RJ Nature; 1980 Feb; 283(5749):772-4. PubMed ID: 6101905 [No Abstract] [Full Text] [Related]
12. Comparison of short and long-lasting effects of pargyline on cerebral dopamine metabolism. Waldmeier PC; Maître L Naunyn Schmiedebergs Arch Pharmacol; 1976 Aug; 294(2):133-40. PubMed ID: 1012333 [TBL] [Abstract][Full Text] [Related]
13. L-dopa upregulates the expression and activities of methionine adenosyl transferase and catechol-O-methyltransferase. Zhao WQ; Latinwo L; Liu XX; Lee ES; Lamango N; Charlton CG Exp Neurol; 2001 Sep; 171(1):127-38. PubMed ID: 11520127 [TBL] [Abstract][Full Text] [Related]
15. L-DOPA: from a biologically inactive amino acid to a successful therapeutic agent. Hornykiewicz O Amino Acids; 2002; 23(1-3):65-70. PubMed ID: 12373520 [TBL] [Abstract][Full Text] [Related]
16. Favorable effect of catechol-O-methyltransferase inhibition by OR-462 in experimental models of Parkinson's disease. Lindén IB; Nissinen E; Etemadzadeh E; Kaakkola S; Männistö P; Pohto P J Pharmacol Exp Ther; 1988 Oct; 247(1):289-93. PubMed ID: 3171977 [TBL] [Abstract][Full Text] [Related]
17. 3-O-methyldopa blocks dopa metabolism in rat corpus striatum. Reches A; Fahn S Ann Neurol; 1982 Sep; 12(3):267-71. PubMed ID: 7137962 [TBL] [Abstract][Full Text] [Related]
18. The metabolism of L-DOPA and L-threo-3,4-dihydroxyphenylserine and their effects on monoamines in the human brain: analysis of the intraventricular fluid from parkinsonian patients. Maruyama W; Naoi M; Narabayashi H J Neurol Sci; 1996 Jul; 139(1):141-8. PubMed ID: 8836986 [TBL] [Abstract][Full Text] [Related]
19. Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease. Wachtel SR; Bencsics C; Kang UJ J Neurochem; 1997 Nov; 69(5):2055-63. PubMed ID: 9349551 [TBL] [Abstract][Full Text] [Related]
20. The mechanism of perturbation in monoamine metabolism by L-dopa therapy: in vivo and in vitro studies. Maruyama W; Naoi M; Takahashi A; Watanabe H; Konagaya Y; Mokuno K; Hasegawa S; Nakahara D J Neural Transm Gen Sect; 1992; 90(3):183-97. PubMed ID: 1363050 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]