These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 497352)

  • 1. Theoretical drug design: 6-azauridine-5'-phosphate--its X-ray crystal structure, potential energy maps, and mechanism of inhibition of orotidine-5'-phosphate decarboxylase.
    Saenger W; Suck D; Knappenberg M; Dirkx J
    Biopolymers; 1979 Aug; 18(8):2015-36. PubMed ID: 497352
    [No Abstract]   [Full Text] [Related]  

  • 2. Polymer-linked 6-azauridine 5'-monophosphate, a resin of high bioaffinity to orotidine-5'-phosphate decarboxylase.
    Rosemeyer H; Seela F
    J Med Chem; 1979 Dec; 22(12):1545-7. PubMed ID: 94096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of orotidine-5'-phosphate decarboxylase by 1-(5'-phospho-beta-d-ribofuranosyl)barbituric acid, 6-azauridine 5'-phosphate, and uridine 5'-phosphate.
    Levine HL; Brody RS; Westheimer FH
    Biochemistry; 1980 Oct; 19(22):4993-9. PubMed ID: 7006681
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
    Janeway CM; Cha S
    Cancer Res; 1977 Dec; 37(12):4382-8. PubMed ID: 922730
    [No Abstract]   [Full Text] [Related]  

  • 5. Pyrazofurin metabolism, enzyme inhibition, and resistance in L5178Y cells.
    Dix DE; Lehman CP; Jakubowski A; Moyer JD; Handschumacher RE
    Cancer Res; 1979 Nov; 39(11):4485-90. PubMed ID: 498080
    [No Abstract]   [Full Text] [Related]  

  • 6. Inhibition of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase of human erythrocytes by purine and pyrimidine nucleotides.
    Tax WJ; Veerkamp JH
    Biochem Pharmacol; 1979 Mar; 28(6):829-31. PubMed ID: 454480
    [No Abstract]   [Full Text] [Related]  

  • 7. Inhibition of human erythrocyte orotidylate decarboxylase.
    Brown GK; O'Sullivan WJ
    Biochem Pharmacol; 1977 Oct; 26(20):1947-50. PubMed ID: 911349
    [No Abstract]   [Full Text] [Related]  

  • 8. Inhibitors of orotate phosphoribosyl-transferase and orotidine-5'-phosphate decarboxylase from mouse Ehrlich ascites cells: a procedure for analyzing the inhibition of a multi-enzyme complex.
    Traut TW; Jones ME
    Biochem Pharmacol; 1977 Dec; 26(23):2291-6. PubMed ID: 563234
    [No Abstract]   [Full Text] [Related]  

  • 9. Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics.
    Poduch E; Bello AM; Tang S; Fujihashi M; Pai EF; Kotra LP
    J Med Chem; 2006 Aug; 49(16):4937-45. PubMed ID: 16884305
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure and inhibition of orotidine 5'-monophosphate decarboxylase from Plasmodium falciparum.
    Langley DB; Shojaei M; Chan C; Lok HC; Mackay JP; Traut TW; Guss JM; Christopherson RI
    Biochemistry; 2008 Mar; 47(12):3842-54. PubMed ID: 18303855
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic resistance to tight-binding inhibitors of enzymes involved in the de novo pyrimidine pathway. Simulation of time-dependent effects.
    Duggleby RG; Christopherson RI
    Eur J Biochem; 1984 Aug; 143(1):221-6. PubMed ID: 6468388
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of orotidine-5'-monophosphate decarboxylase--discoveries and lessons.
    Kotra LP; Pai EF
    Nucleic Acids Symp Ser (Oxf); 2008; (52):85-6. PubMed ID: 18776265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: crystallographic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase.
    Wise EL; Yew WS; Gerlt JA; Rayment I
    Biochemistry; 2004 Jun; 43(21):6438-46. PubMed ID: 15157078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystallization of yeast orotidine 5'-monophosphate decarboxylase complexed with 1-(5'-phospho-beta-D-ribofuranosyl) barbituric acid.
    Bell JB; Jones ME; Carter CW
    Proteins; 1991; 9(2):143-51. PubMed ID: 2008434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of carbocyclic orotidine analogs as potential orotidine decarboxylase inhibitors.
    Song GY; Naguib FN; el Kouni MH; Chu CK
    Nucleosides Nucleotides Nucleic Acids; 2001 Dec; 20(12):1915-25. PubMed ID: 11794797
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
    Purohit MK; Poduch E; Wei LW; Crandall IE; To T; Kain KC; Pai EF; Kotra LP
    J Med Chem; 2012 Nov; 55(22):9988-97. PubMed ID: 22991951
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Theoretical studies of the effect of thio substitution on orotidine monophosphate decarboxylase substrates.
    Phillips LM; Lee JK
    J Org Chem; 2005 Feb; 70(4):1211-21. PubMed ID: 15704953
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coordinate overproduction of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in hamster cells resistant to pyrazofurin and 6-azauridine.
    Suttle DP; Stark GR
    J Biol Chem; 1979 Jun; 254(11):4602-7. PubMed ID: 220255
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
    Wittmann JG; Heinrich D; Gasow K; Frey A; Diederichsen U; Rudolph MG
    Structure; 2008 Jan; 16(1):82-92. PubMed ID: 18184586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiple molecular forms of orotidylate decarboxylase from human liver.
    Campbell MT; Gallagher ND; O'Sullivan WJ
    Biochem Med; 1977 Apr; 17(2):128-40. PubMed ID: 856170
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 5.