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2. Irreversible enzyme inhibitors. CXX. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-substituted 2,4-diamino-5-phenylpyrimidines with tissue specificity. Baker BR; Huang PC J Med Chem; 1968 May; 11(3):495-500. PubMed ID: 5241409 [No Abstract] [Full Text] [Related]
3. Irreversible enzyme inhibitors. CXIX. Active-site-directed irreversible inhibitors of dihydrofolic reductase with tissue specificity derived from 2,4,6-triaminopyrimidine with a terminal sulfonyl fluoride at the 5 position. Baker BR; Meyer RB J Med Chem; 1968 May; 11(3):489-94. PubMed ID: 5241408 [No Abstract] [Full Text] [Related]
4. Irreversible enzyme inhibitors. CXII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine substituted with a terminal sulfonyl fluoride. II. Baker BR; Lourens GJ J Med Chem; 1968 Jan; 11(1):38-41. PubMed ID: 5237173 [No Abstract] [Full Text] [Related]
5. Irreversible enzyme inhibitors. CXVII. Hydrophobic bonding to dihydrofolic reductase. XI. Comparison of the enzyme from Walker 256, rat liver, and L1210 mouse leukemia. Baker BR J Med Chem; 1968 May; 11(3):483-6. PubMed ID: 5241406 [No Abstract] [Full Text] [Related]
6. Irreversible enzyme inhibitors. CLX. Some factors in cell wall transport of active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines. Baker BR; Janson EE; Vermeulen NM J Med Chem; 1969 Sep; 12(5):898-902. PubMed ID: 5812208 [No Abstract] [Full Text] [Related]
7. Irreversible enzyme inhibitors. CXXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. VI. Further studies on effects of substitution on the propionamide bridge on isozyme specificity. Baker BR; Lourens GJ J Med Chem; 1969 Jan; 12(1):92-4. PubMed ID: 5763049 [No Abstract] [Full Text] [Related]
8. Irreversible enzyme inhibitors. CX. Candidate irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine. IV. Baker BR; Lourens GJ J Med Chem; 1968 Jan; 11(1):34-7. PubMed ID: 5237172 [No Abstract] [Full Text] [Related]
9. Irreversible enzyme inhibitors. 138. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenethyl)-- 2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with a terminal sulfonyl fluoride. Baker BR; Vermeulen NM J Med Chem; 1969 Jan; 12(1):89-91. PubMed ID: 5763048 [No Abstract] [Full Text] [Related]
10. Irreversible enzyme inhibitors. 143. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-(p-aminophenoxypropyl)-2,4-diamino-6-methylpyrimidine with a terminal sulfonyl fluoride. Baker BR; Meyer RB J Med Chem; 1969 Jan; 12(1):108-11. PubMed ID: 5763004 [No Abstract] [Full Text] [Related]
11. Irreversible enzyme inhibitors. CXXXVII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenoxymethyl)-2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine bearing a terminal sulfonyl fluoride. Baker BR; Vermeulen NM J Med Chem; 1969 Jan; 12(1):86-8. PubMed ID: 5763047 [No Abstract] [Full Text] [Related]
13. Irreversible enzyme inhibitors. CXXXVI. 2,4-Diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonylbenzamido)phenoxymethyl]pyrimidine, an active-site-directed irreversible inhibitor of dihydrofolic reductase. Effect of structure on isozyme specificity. Baker BR; Vermeulen NM J Med Chem; 1969 Jan; 12(1):82-5. PubMed ID: 5763046 [No Abstract] [Full Text] [Related]
14. Irrevesible enzyme inhibitors. CLI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-(p-aminophenylbutyl)-2,4-diaminopyrimidines with a terminal sulfonyl fluoride. Baker BR; Meyer RB J Med Chem; 1969 Mar; 12(2):224-7. PubMed ID: 5254099 [No Abstract] [Full Text] [Related]
15. Irreversible enzyme inhibitors. 108. 6-(p-chloroacetylanilinomethyl)-5-(p-chlorophenyl)-2,4-diaminopyrimidine, an active-site-directed irreversible inhibitor of dihydrofolic reductase. Baker BR; Huang PC; Pogolotti AL J Med Chem; 1967 Nov; 10(6):1134-8. PubMed ID: 6056043 [No Abstract] [Full Text] [Related]
16. Irreversible enzyme inhibitors. CXXXVI. 2,4-Diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonylbenz amido) phenoxymethyl] pyrimidine, an active-site-directed irreverisible inhibitor of dihydrofolic reductase. Effect of structure on isozyme specificity. Baker BR; Vermeulen NM J Med Chem; 1969 Jan; 12(1):82-5. PubMed ID: 5777842 [No Abstract] [Full Text] [Related]
17. Irreversible enzyme inhibitors. CXLII. Further studies on active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-(p-Aminophenoxypropyl)-2,4,6-triaminopyrimidine bearing a terminal sulfonyl fluoride. Baker BR; Meyer RB J Med Chem; 1969 Jan; 12(1):104-7. PubMed ID: 5763003 [No Abstract] [Full Text] [Related]
18. Irreversible enzyme inhibitors. CLXXVII. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines. II. Baker BR; Vermeulen NM J Med Chem; 1970 Nov; 13(6):1154-60. PubMed ID: 5479856 [No Abstract] [Full Text] [Related]
19. Irreversible enzyme inhibitors. CXXXV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(p-fluorosulfonyl-phenylureido)phenoxymethyl]pyrimidine. Baker BR; Vermeulen NM J Med Chem; 1969 Jan; 12(1):79-81. PubMed ID: 5763045 [No Abstract] [Full Text] [Related]