210 related articles for article (PubMed ID: 560248)
1. Antimitotic and antitubulin activity of the tumor inhibitor steganacin.
Wang RW; Rebhum LI; Kupchan SM
Cancer Res; 1977 Sep; 37(9):3071-9. PubMed ID: 560248
[TBL] [Abstract][Full Text] [Related]
2. Steganacin: an inhibitor of HeLa cell growth and microtubule assembly in vitro.
Schiff PB; Kende AS; Horwitz SB
Biochem Biophys Res Commun; 1978 Nov; 85(2):737-46. PubMed ID: 736931
[No Abstract] [Full Text] [Related]
3. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
Bai R; Cichacz ZA; Herald CL; Pettit GR; Hamel E
Mol Pharmacol; 1993 Oct; 44(4):757-66. PubMed ID: 8232226
[TBL] [Abstract][Full Text] [Related]
4. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
Gupta K; Bishop J; Peck A; Brown J; Wilson L; Panda D
Biochemistry; 2004 Jun; 43(21):6645-55. PubMed ID: 15157098
[TBL] [Abstract][Full Text] [Related]
5. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
Jiang JD; Davis AS; Middleton K; Ling YH; Perez-Soler R; Holland JF; Bekesi JG
Cancer Res; 1998 Dec; 58(23):5389-95. PubMed ID: 9850070
[TBL] [Abstract][Full Text] [Related]
6. Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization.
Batra JK; Kang GJ; Jurd L; Hamel E
Biochem Pharmacol; 1988 Jul; 37(13):2595-602. PubMed ID: 3390218
[TBL] [Abstract][Full Text] [Related]
7. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
Perchellet EM; Ladesich JB; Magill MJ; Chen Y; Hua DH; Perchellet JP
Anticancer Drugs; 1999 Jun; 10(5):489-504. PubMed ID: 10477169
[TBL] [Abstract][Full Text] [Related]
8. Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
Batra JK; Jurd L; Hamel E
Mol Pharmacol; 1985 Jan; 27(1):94-102. PubMed ID: 3965931
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues.
Blokhin AV; Yoo HD; Geralds RS; Nagle DG; Gerwick WH; Hamel E
Mol Pharmacol; 1995 Sep; 48(3):523-31. PubMed ID: 7565634
[TBL] [Abstract][Full Text] [Related]
10. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
[TBL] [Abstract][Full Text] [Related]
11. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin.
Bhattacharyya B; Panda D; Gupta S; Banerjee M
Med Res Rev; 2008 Jan; 28(1):155-83. PubMed ID: 17464966
[TBL] [Abstract][Full Text] [Related]
12. Structural and biochemical comparison of the anti-mitotic agents colchicine, combretastatin A4 and amphethinile.
McGown AT; Fox BW
Anticancer Drug Des; 1989 Mar; 3(4):249-54. PubMed ID: 2930627
[TBL] [Abstract][Full Text] [Related]
13. Oxalone and lactone moieties of podophyllotoxin exhibit properties of both the B and C rings of colchicine in its binding with tubulin.
Gupta S; Das L; Datta AB; Poddar A; Janik ME; Bhattacharyya B
Biochemistry; 2006 May; 45(20):6467-75. PubMed ID: 16700557
[TBL] [Abstract][Full Text] [Related]
14. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
[TBL] [Abstract][Full Text] [Related]
15. Correlation of tubulin-binding and antitumor activities of podophyllotoxin analogs.
Kelleher JK
Cancer Treat Rep; 1978 Oct; 62(10):1443-7. PubMed ID: 101303
[TBL] [Abstract][Full Text] [Related]
16. Antimitotic activity of the potent tumor inhibitor maytansine.
Remillard S; Rebhun LI; Howie GA; Kupchan SM
Science; 1975 Sep; 189(4207):1002-5. PubMed ID: 1241159
[TBL] [Abstract][Full Text] [Related]
17. The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
Kowalski RJ; Giannakakou P; Gunasekera SP; Longley RE; Day BW; Hamel E
Mol Pharmacol; 1997 Oct; 52(4):613-22. PubMed ID: 9380024
[TBL] [Abstract][Full Text] [Related]
18. Mechanism of action of E7010, an orally active sulfonamide antitumor agent: inhibition of mitosis by binding to the colchicine site of tubulin.
Yoshimatsu K; Yamaguchi A; Yoshino H; Koyanagi N; Kitoh K
Cancer Res; 1997 Aug; 57(15):3208-13. PubMed ID: 9242451
[TBL] [Abstract][Full Text] [Related]
19. Cornigerine, a potent antimitotic Colchicum alkaloid of unusual structure. Interactions with tubulin.
Hamel E; Ho HH; Kang GJ; Lin CM
Biochem Pharmacol; 1988 Jun; 37(12):2445-9. PubMed ID: 3390207
[TBL] [Abstract][Full Text] [Related]
20. Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism.
Derry WB; Wilson L; Jordan MA
Cancer Res; 1998 Mar; 58(6):1177-84. PubMed ID: 9515803
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
