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9. Irreversible enzyme inhibitors. CXXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. VI. Further studies on effects of substitution on the propionamide bridge on isozyme specificity. Baker BR; Lourens GJ J Med Chem; 1969 Jan; 12(1):92-4. PubMed ID: 5763049 [No Abstract] [Full Text] [Related]
10. Irreversible enzyme inhibitors. CLXXVI. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine by ether bridging to a terminal sulfonyl fluoride. Baker BR; Ashton WT J Med Chem; 1970 Nov; 13(6):1149-54. PubMed ID: 5479855 [No Abstract] [Full Text] [Related]
11. Irreversible enzyme inhibitors. CLV. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 1-[4-(omega-aminoalkoxy)-3-chlorophenyl]-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazines bearing a terminal sulfonyl fluoride. Baker BR; Janson EE J Med Chem; 1969 Jul; 12(4):672-6. PubMed ID: 5793160 [No Abstract] [Full Text] [Related]
12. Irreversible enzyme inhibitors. 196. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine and bearing a terminal phenyl sulfonate group. Baker BR; Ashton WT J Med Chem; 1972 Sep; 15(9):945-7. PubMed ID: 5051014 [No Abstract] [Full Text] [Related]
14. Irreversible enzyme inhibitors. 173. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine. Baker BR; Vermeulen NM; Ashton WT; Ryan AJ J Med Chem; 1970 Nov; 13(6):1130-40. PubMed ID: 5479852 [No Abstract] [Full Text] [Related]
15. Irreversible enzyme inhibitors. CXVII. Hydrophobic bonding to dihydrofolic reductase. XI. Comparison of the enzyme from Walker 256, rat liver, and L1210 mouse leukemia. Baker BR J Med Chem; 1968 May; 11(3):483-6. PubMed ID: 5241406 [No Abstract] [Full Text] [Related]
16. Active-site directed irreversible inhibitors of dihydrofolate reductase. Baker BR Ann N Y Acad Sci; 1971 Nov; 186():214-26. PubMed ID: 4943574 [No Abstract] [Full Text] [Related]
17. Irreversible enzyme inhibitors. CXX. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-substituted 2,4-diamino-5-phenylpyrimidines with tissue specificity. Baker BR; Huang PC J Med Chem; 1968 May; 11(3):495-500. PubMed ID: 5241409 [No Abstract] [Full Text] [Related]
18. Irreversible enzyme inhibitors. CV. Differential irreversible inhibition of vertebrate dihydrofolic reductases by derivatives of 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazines substituted with a terminal sulfonyl fluoride. Baker BR; Lourens GJ J Med Chem; 1967 Nov; 10(6):1113-22. PubMed ID: 6056040 [No Abstract] [Full Text] [Related]
19. Irreversible enzyme inhibitors. 108. p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. IV. Effects of substitution on the propionamide bridge on isozyme specificity. Baker BR; Lourens GJ J Med Chem; 1968 Jul; 11(4):672-7. PubMed ID: 5244345 [No Abstract] [Full Text] [Related]
20. Irreversible enzyme inhibitors. CXXVII. p-(2,6-diamino-1,2-dihydro--2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. 3. Effects of modification of the propionamide bridge on isozyme specificity. Baker BR; Luorens GJ J Med Chem; 1968 Jul; 11(4):666-72. PubMed ID: 5244344 [No Abstract] [Full Text] [Related] [Next] [New Search]