BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 6088753)

  • 1. Difference in epoxides formation and their further metabolism between delta 9- and delta 8-tetrahydrocannabinols by human liver microsomes.
    Yamamoto I; Narimatsu S; Shimonishi T; Watanabe K; Yoshimura H
    J Pharmacobiodyn; 1984 Apr; 7(4):254-62. PubMed ID: 6088753
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and determination of 8 alpha, 9 alpha-epoxyhexahydrocannabinol as a metabolite of delta 8-tetrahydrocannabinol of mice in vitro.
    Narimatsu S; Watanabe K; Yamamoto I; Yoshimura H
    Xenobiotica; 1982 Sep; 12(9):561-5. PubMed ID: 6297175
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The obligatory intermediacy of 16,17 alpha- and 16,17 beta-epoxides in the biotransformation of androsta-5,16-dien-3 beta-ol to androst-5-ene-3 beta, 16 alpha, 17 beta- and -3 beta, 16 beta, 17 alpha-triols by male rat liver microsomes.
    Watabe T; Komatsu T; Kobayashi K; Isobe M; Ozawa N; Saitoh Y
    J Biol Chem; 1985 Jul; 260(15):8716-20. PubMed ID: 4019450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epoxide-diol pathway of delta 1-THC in the rat in vitro.
    Ben-Zvi Z
    Xenobiotica; 1980 Nov; 10(11):805-9. PubMed ID: 6258334
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereospecific hydrolysis of 8 alpha,9 alpha- and 8 beta,9 beta-epoxyhexahydrocannabinols in the mouse in vivo and in vitro.
    Narimatsu S; Yamamoto I; Yoshimura H
    Xenobiotica; 1985 Mar; 15(3):227-35. PubMed ID: 2992175
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 9 alpha, 10 alpha-epoxyhexahydrocannabinol formation from delta 9-tetrahydrocannabinol by liver microsomes of phenobarbital-treated mice and its pharmacological activities in mice.
    Narimatsu S; Yamamoto I; Watanabe K; Yoshimura H
    J Pharmacobiodyn; 1983 Aug; 6(8):558-64. PubMed ID: 6315913
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic disposition of 8 alpha, 9 alpha- and 8 beta, 9 beta-epoxyhexahydrocannabinols in the mouse.
    Narimatsu S; Watanabe K; Shimonishi T; Matsubara K; Yamamoto I; Yoshimura H
    J Pharmacobiodyn; 1984 Sep; 7(9):671-6. PubMed ID: 6098641
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro metabolic formation of a new metabolite, 6 beta-hydroxymethyl-delta 9-tetrahydrocannabinol from cannabidiol through an epoxide intermediate and its pharmacological effects on mice.
    Nagai K; Watanabe K; Narimatsu S; Gohda H; Matsunaga T; Yamamoto I; Yoshimura H
    Biol Pharm Bull; 1993 Oct; 16(10):1008-13. PubMed ID: 8287029
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epoxidation of androsta-5,16-dien-3 beta-ol by hepatic microsomal lipid peroxidation.
    Watabe T; Kobayashi K; Saitoh Y; Komatsu T; Ozawa N; Tsubaki A; Endoh K; Hiratsuka A
    J Biol Chem; 1986 Mar; 261(7):3200-7. PubMed ID: 3949767
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo effects of tetrahydrocannabinols and their eight monooxygenated metabolites of the hepatic microsomal drug-metabolizing enzyme systems of mice.
    Watanabe K; Arai M; Narimatsu S; Yamamoto I; Yoshimura H
    J Pharmacobiodyn; 1987 Oct; 10(10):580-6. PubMed ID: 2831334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereoselective formations of K-region and non-K-region epoxides in the metabolism of chrysene by rat liver microsomal cytochrome P-450 isozymes.
    Yang SK; Bao ZP
    Mol Pharmacol; 1987 Jul; 32(1):73-80. PubMed ID: 3037304
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes.
    Watanabe K; Yamaori S; Funahashi T; Kimura T; Yamamoto I
    Life Sci; 2007 Mar; 80(15):1415-9. PubMed ID: 17303175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of hepatic microsomal oxidation of 11-hydroxy-delta 8-tetrahydrocannabinol to 11-oxo-delta 8-tetrahydrocannabinol. Evidence for hydration of the aldehyde formed.
    Watanabe K; Matsunaga T; Narimatsu S; Yamamoto I; Yoshimura H
    J Pharmacobiodyn; 1992 Jun; 15(6):311-7. PubMed ID: 1331394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sex difference in the oxidative metabolism of delta 9-tetrahydrocannabinol in the rat.
    Narimatsu S; Watanabe K; Yamamoto I; Yoshimura H
    Biochem Pharmacol; 1991 Apr; 41(8):1187-94. PubMed ID: 1848985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolites of the 1',2'-dimethylheptyl analogue of delta-8-tetrahydrocannabinol in the mouse and their identification by gas chromatography/mass spectrometry.
    Harvey DJ; Brown NK
    Biomed Environ Mass Spectrom; 1990 Oct; 19(10):619-27. PubMed ID: 1962732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid.
    Chacos N; Falck JR; Wixtrom C; Capdevila J
    Biochem Biophys Res Commun; 1982 Feb; 104(3):916-22. PubMed ID: 6803794
    [No Abstract]   [Full Text] [Related]  

  • 17. Metabolism of delta 9-tetrahydrocannabinol by cytochrome P450 isozymes purified from hepatic microsomes of monkeys.
    Matsunaga T; Iwawaki Y; Watanabe K; Yamamoto I; Kageyama T; Yoshimura H
    Life Sci; 1995; 56(23-24):2089-95. PubMed ID: 7776836
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential stereoselectivity of cytochromes P-450b and P-450c in the formation of naphthalene and anthracene 1,2-oxides. The role of epoxide hydrolase in determining the enantiomer composition of the 1,2-dihydrodiols formed.
    van Bladeren PJ; Sayer JM; Ryan DE; Thomas PE; Levin W; Jerina DM
    J Biol Chem; 1985 Aug; 260(18):10226-35. PubMed ID: 4019509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-delta(8)-tetrahydrocannabinol in human liver microsomes.
    Matsunaga T; Kishi N; Higuchi S; Watanabe K; Ohshima T; Yamamoto I
    Drug Metab Dispos; 2000 Nov; 28(11):1291-6. PubMed ID: 11038155
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A cytochrome P450 isozyme having aldehyde oxygenase activity plays a major role in metabolizing cannabinoids by mouse hepatic microsomes.
    Watanabe K; Narimatsu S; Matsunaga T; Yamamoto I; Yoshimura H
    Biochem Pharmacol; 1993 Aug; 46(3):405-11. PubMed ID: 8394082
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.