BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 6099893)

  • 1. Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs.
    De Clercq E; Walker RT
    Pharmacol Ther; 1984; 26(1):1-44. PubMed ID: 6099893
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase.
    Grignet-Debrus C; Cool V; Baudson N; Degrève B; Balzarini J; De Leval L; Debrus S; Velu T; Calberg-Bacq CM
    Cancer Gene Ther; 2000 Feb; 7(2):215-23. PubMed ID: 10770629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.
    Balzarini J; McGuigan C
    Biochim Biophys Acta; 2002 Jul; 1587(2-3):287-95. PubMed ID: 12084470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.
    Herdewijn P; De Clercq E; Balzarini J; Vanderhaeghe H
    J Med Chem; 1985 May; 28(5):550-5. PubMed ID: 2985782
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly selective cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine derivatives for murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Seno T
    Mol Pharmacol; 1985 Dec; 28(6):581-7. PubMed ID: 3001499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
    Balzarini J; De Clercq E; Verbruggen A; Crumpacker C; Ayusawa D; Seno T
    Anticancer Res; 1986; 6(5):1077-84. PubMed ID: 2432829
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of (E)-5-(2-bromovinyl)uracil and related pyrimidine nucleosides as antiviral agents for herpes viruses.
    Choi Y; Li L; Grill S; Gullen E; Lee CS; Gumina G; Tsujii E; Cheng YC; Chu CK
    J Med Chem; 2000 Jun; 43(13):2538-46. PubMed ID: 10891113
    [TBL] [Abstract][Full Text] [Related]  

  • 8. (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
    De Clercq E
    Med Res Rev; 2005 Jan; 25(1):1-20. PubMed ID: 15389733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Shimizu K; Seno T
    Mol Pharmacol; 1987 Sep; 32(3):410-6. PubMed ID: 2823092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro susceptibility of varicella-zoster virus to E-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
    De Clercq E; Descamps J; Ogata M; Shigeta S
    Antimicrob Agents Chemother; 1982 Jan; 21(1):33-8. PubMed ID: 6282207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Balzarini J; Baumgartner H; Bodenteich M; De Clercq E; Griengl H
    J Med Chem; 1989 Aug; 32(8):1861-5. PubMed ID: 2547072
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication.
    Balzarini J; McGuigan C
    J Antimicrob Chemother; 2002 Jul; 50(1):5-9. PubMed ID: 12096000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster.
    De Clercq E
    Biochem Pharmacol; 2004 Dec; 68(12):2301-15. PubMed ID: 15548377
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase.
    Sienaert R; Naesens L; Brancale A; De Clercq E; McGuigan C; Balzarini J
    Mol Pharmacol; 2002 Feb; 61(2):249-54. PubMed ID: 11809847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxycytidine-related compounds.
    Jones AS; Sayers JR; Walker RT; De Clercq E
    J Med Chem; 1988 Jan; 31(1):268-71. PubMed ID: 2826786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Harris SA; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
    Antivir Chem Chemother; 2001 Sep; 12(5):293-300. PubMed ID: 11900348
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The antiviral spectrum of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    De Clercq E
    J Antimicrob Chemother; 1984 Aug; 14 Suppl A():85-95. PubMed ID: 6092320
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative efficacy of antiherpes drugs against various strains of varicella-zoster virus.
    Shigeta S; Yokota T; Iwabuchi T; Baba M; Konno K; Ogata M; De Clercq E
    J Infect Dis; 1983 Mar; 147(3):576-84. PubMed ID: 6300257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.
    Wigerinck P; Pannecouque C; Snoeck R; Claes P; De Clercq E; Herdewijn P
    J Med Chem; 1991 Aug; 34(8):2383-9. PubMed ID: 1652017
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer.
    Degrève B; Andrei G; Izquierdo M; Piette J; Morin K; Knaus EE; Wiebe LI; Basrah I; Walker RT; De Clercq E; Balzarini J
    Gene Ther; 1997 Oct; 4(10):1107-14. PubMed ID: 9415318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.