BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 6128189)

  • 21. Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506.
    Iwasaki K; Shiraga T; Matsuda H; Nagase K; Tokuma Y; Hata T; Fujii Y; Sakuma S; Fujitsu T; Fujikawa A
    Drug Metab Dispos; 1995 Jan; 23(1):28-34. PubMed ID: 7536652
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW; Dean DC; Miller RR; Rasmusson GH; Chiu SH
    Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations.
    Umehara K; Kudo S; Hirao Y; Morita S; Uchida M; Odomi M; Miyamoto G
    Drug Metab Dispos; 2000 Aug; 28(8):887-94. PubMed ID: 10901696
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP; Yan J; Fu PP; Chou MW
    Toxicol Lett; 2005 Mar; 155(3):411-20. PubMed ID: 15649625
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C; Gelboin HV; Park SS; Pearce R; Parkinson A; Kupfer D
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Analogues of chloramphenicol as mechanism-based inactivators of rat liver cytochrome P-450: modifications of the propanediol side chain, the p-nitro group, and the dichloromethyl moiety.
    Miller NE; Halpert J
    Mol Pharmacol; 1986 Apr; 29(4):391-8. PubMed ID: 3702858
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken.
    Liu ZY; Huang LL; Chen DM; Dai MH; Tao YF; Yuan ZH
    Toxicol Lett; 2010 May; 195(1):51-9. PubMed ID: 20219653
    [TBL] [Abstract][Full Text] [Related]  

  • 28. In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
    Ishii Y; Mukoyama H; Ohtawa M
    Drug Metab Dispos; 1994; 22(1):79-84. PubMed ID: 8149894
    [TBL] [Abstract][Full Text] [Related]  

  • 29. N-oxidation and N-demethylation of methylephedrine by rat-liver microsomes.
    Inoue T; Tanaka K
    Xenobiotica; 1990 Mar; 20(3):265-71. PubMed ID: 2336838
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Selective inhibition by chloramphenicol of cytochrome P-450 isozymes in rat lung and liver involved in the hydroxylation of n-hexane.
    Näslund BM; Halpert J
    J Pharmacol Exp Ther; 1984 Oct; 231(1):16-22. PubMed ID: 6491971
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
    Ferrara R; Tolando R; King LJ; Manno M
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):420-8. PubMed ID: 9144458
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ; Webb CD; Yao M; Weedon AC; Bend JR
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Metabolism of doxophylline by rat liver microsomes.
    Grosa G; Franzone JS; Biglino G
    Drug Metab Dispos; 1986; 14(2):267-70. PubMed ID: 2870905
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
    Raza H; King RS; Squires RB; Guengerich FP; Miller DW; Freeman JP; Lang NP; Kadlubar FF
    Drug Metab Dispos; 1996 Apr; 24(4):395-400. PubMed ID: 8801053
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanism of defluorination of enflurane. Identification of an organic metabolite in rat and man.
    Burke TR; Branchflower RV; Lees DE; Pohl LR
    Drug Metab Dispos; 1981; 9(1):19-24. PubMed ID: 6111426
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolysis products in rats.
    Nakamura Y; Sugihara K; Sone T; Isobe M; Ohta S; Kitamura S
    Toxicology; 2007 Jun; 235(3):176-84. PubMed ID: 17451859
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.
    Remmel RP; Crews BC; Kozak KR; Kalgutkar AS; Marnett LJ
    Drug Metab Dispos; 2004 Jan; 32(1):113-22. PubMed ID: 14709628
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Metabolism of 2-chloroethyl nitrosocarbamoylcystamine by rat liver subcellular fractions.
    Godeneche D; Madelmont JC; Moreau MF; Duprat J; Plagne R; Meyniel G
    Drug Metab Dispos; 1986; 14(1):112-7. PubMed ID: 2868853
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites.
    Kohno Y; Kitamura S; Sanoh S; Sugihara K; Fujimoto N; Ohta S
    Drug Metab Dispos; 2005 Aug; 33(8):1115-23. PubMed ID: 15863696
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.
    Jeffery EH; Mannering GJ
    Mol Pharmacol; 1983 May; 23(3):748-57. PubMed ID: 6865917
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.