These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 6143829)

  • 41. Reaction of aspartate aminotransferase with L-erythro-3-hydroxyaspartate: involvement of Tyr70 in stabilization of the catalytic intermediates.
    Hayashi H; Kagamiyama H
    Biochemistry; 1995 Jul; 34(29):9413-23. PubMed ID: 7626611
    [TBL] [Abstract][Full Text] [Related]  

  • 42. The stereospecific labilization of the C-4' pro-S hydrogen of pyridoxamine 5'-phosphate is abolished in (Lys258----Ala) aspartate aminotransferase.
    Kochhar S; Finlayson WL; Kirsch JF; Christen P
    J Biol Chem; 1987 Aug; 262(24):11446-8. PubMed ID: 3114245
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Domain closure in mitochondrial aspartate aminotransferase.
    McPhalen CA; Vincent MG; Picot D; Jansonius JN; Lesk AM; Chothia C
    J Mol Biol; 1992 Sep; 227(1):197-213. PubMed ID: 1522585
    [TBL] [Abstract][Full Text] [Related]  

  • 44. [Study of the reorientation of coenzyme in active sites of aspartate-aminotransferase isoenzymes using linear dichroism method].
    Rozenberg MV; Makarov VL; Torchinskiĭ IuM
    Mol Biol (Mosk); 1988; 22(4):1132-40. PubMed ID: 3185533
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Substitution of an arginyl residue for the active site lysyl residue (Lys258) of aspartate aminotransferase.
    Kuramitsu S; Inoue Y; Tanase S; Morino Y; Kagamiyama H
    Biochem Biophys Res Commun; 1987 Jul; 146(2):416-21. PubMed ID: 3113421
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The open/closed conformational equilibrium of aspartate aminotransferase. Studies in the crystalline state and with a fluorescent probe in solution.
    Picot D; Sandmeier E; Thaller C; Vincent MG; Christen P; Jansonius JN
    Eur J Biochem; 1991 Mar; 196(2):329-41. PubMed ID: 2007402
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Stereospecific labilization of the C-4' pro-S hydrogen of pyridoxamine 5'-phosphate in aspartate aminotransferase. Activators and inhibitors.
    Tobler HP; Gehring H; Christen P
    J Biol Chem; 1987 Jul; 262(19):8985-9. PubMed ID: 2885326
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Role of an active site residue analyzed by combination of mutagenesis and coenzyme analog.
    Yano T; Hinoue Y; Chen VJ; Metzler DE; Miyahara I; Hirotsu K; Kagamiyama H
    J Mol Biol; 1993 Dec; 234(4):1218-29. PubMed ID: 8263922
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.
    Storici P; Capitani G; Müller R; Schirmer T; Jansonius JN
    J Mol Biol; 1999 Jan; 285(1):297-309. PubMed ID: 9878407
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
    Mizuguchi H; Hayashi H; Okada K; Miyahara I; Hirotsu K; Kagamiyama H
    Biochemistry; 2001 Jan; 40(2):353-60. PubMed ID: 11148029
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Crystal structure of phosphoserine aminotransferase from Escherichia coli at 2.3 A resolution: comparison of the unligated enzyme and a complex with alpha-methyl-l-glutamate.
    Hester G; Stark W; Moser M; Kallen J; Marković-Housley Z; Jansonius JN
    J Mol Biol; 1999 Feb; 286(3):829-50. PubMed ID: 10024454
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis.
    Hayashi H; Mizuguchi H; Miyahara I; Nakajima Y; Hirotsu K; Kagamiyama H
    J Biol Chem; 2003 Mar; 278(11):9481-8. PubMed ID: 12488449
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Chemical modification of a functional arginyl residue (Arg 292) of mitochondrial aspartate aminotransferase. Identification as the binding site for the distal carboxylate group of the substrate.
    Sandmeier E; Christen P
    J Biol Chem; 1982 Jun; 257(12):6745-50. PubMed ID: 7085600
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Noncovalent binding of a reaction intermediate by a designed helix-loop-helix motif-implications for catalyst design.
    Allert M; Baltzer L
    Chembiochem; 2003 Apr; 4(4):306-18. PubMed ID: 12672110
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms.
    Jäger J; Moser M; Sauder U; Jansonius JN
    J Mol Biol; 1994 Jun; 239(2):285-305. PubMed ID: 8196059
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099.
    Yoshikane Y; Yokochi N; Yamasaki M; Mizutani K; Ohnishi K; Mikami B; Hayashi H; Yagi T
    J Biol Chem; 2008 Jan; 283(2):1120-7. PubMed ID: 17989071
    [TBL] [Abstract][Full Text] [Related]  

  • 57. A simple method for determination of stereospecificity of aminotransferases for C-4' hydrogen transfer of the coenzyme.
    Nishimura K; Ito J; Yoshimura T; Esaki N; Soda K
    Bioorg Med Chem; 1994 Jul; 2(7):605-7. PubMed ID: 7858965
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
    Okamoto A; Nakai Y; Hayashi H; Hirotsu K; Kagamiyama H
    J Mol Biol; 1998 Jul; 280(3):443-61. PubMed ID: 9665848
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
    Okada K; Hirotsu K; Hayashi H; Kagamiyama H
    Biochemistry; 2001 Jun; 40(25):7453-63. PubMed ID: 11412098
    [TBL] [Abstract][Full Text] [Related]  

  • 60. The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
    Almo SC; Smith DL; Danishefsky AT; Ringe D
    Protein Eng; 1994 Mar; 7(3):405-12. PubMed ID: 7909946
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.