These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

449 related articles for article (PubMed ID: 6173121)

  • 1. The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
    Fernandes DJ; Moroson BA; Bertino JR
    Cancer Treat Rep; 1981; 65 Suppl 1():29-35. PubMed ID: 6173121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.
    Fernandes DJ; Bertino JR
    Proc Natl Acad Sci U S A; 1980 Oct; 77(10):5663-7. PubMed ID: 6160578
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequential methotrexate and 5-fluorouracil: mechanisms of synergy.
    Bertino JR; Mini E; Fernandes DJ
    Semin Oncol; 1983 Jun; 10(2 Suppl 2):2-5. PubMed ID: 6867754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM
    Cancer Res; 1977 Feb; 37(2):408-12. PubMed ID: 832265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of methotrexate polyglutamates in methotrexate- and sequential methotrexate-5-fluorouracil-mediated cell kill.
    McGuire JJ; Mini E; Hsieh P; Bertino JR
    Cancer Res; 1985 Dec; 45(12 Pt 1):6395-400. PubMed ID: 2415244
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
    Samuels LL; Moccio DM; Sirotnak FM
    Cancer Res; 1985 Apr; 45(4):1488-95. PubMed ID: 3978616
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Formation of 7-hydroxymethotrexate polyglutamyl derivatives and their cytotoxicity in human chronic myelogenous leukemia cells, in vitro.
    Fabre G; Goldman ID
    Cancer Res; 1985 Jan; 45(1):80-5. PubMed ID: 2578101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.
    Curt GA; Jolivet J; Carney DN; Bailey BD; Drake JC; Clendeninn NJ; Chabner BA
    J Clin Invest; 1985 Oct; 76(4):1323-9. PubMed ID: 2414316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quinazoline thymidylate synthase inhibitors: methods for assessing the contribution of polyglutamation to their in vitro activity.
    Jackman AL; Kimbell R; Brown M; Brunton L; Boyle FT
    Anticancer Drug Des; 1995 Oct; 10(7):555-72. PubMed ID: 7495479
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil.
    Danhauser LL; Heimer R; Cadman E
    Cancer Chemother Pharmacol; 1985; 15(3):214-9. PubMed ID: 3876889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [The metabolism of high-molecular-weight substances in cells and the effect of anticancer drugs].
    Kanamaru R; Kakuta H; Sato T; Ishioka C; Konishi Y; Wakui A; Dei T
    Gan To Kagaku Ryoho; 1987 Mar; 14(3 Pt 2):837-44. PubMed ID: 3566294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS; Galivan J; Wright JE; Rosowsky A
    Mol Pharmacol; 1994 Apr; 45(4):783-91. PubMed ID: 7514264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rescue effect of exogenous reduced folates on methotrexate polyglutamylation and dihydrofolate reductase activity in L1210 cells.
    Balińska M
    Acta Biochim Pol; 1988; 35(3):199-205. PubMed ID: 2469275
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates.
    Goldman ID; Matherly LH
    NCI Monogr; 1987; (5):17-26. PubMed ID: 2448654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
    Koizumi S; Curt GA; Fine RL; Griffin JD; Chabner BA
    J Clin Invest; 1985 Mar; 75(3):1008-14. PubMed ID: 2579975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH; Barlowe CK; Goldman ID
    Cancer Res; 1986 Feb; 46(2):588-93. PubMed ID: 2416428
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate.
    Zhao R; Babani S; Gao F; Liu L; Goldman ID
    Clin Cancer Res; 2000 Sep; 6(9):3687-95. PubMed ID: 10999762
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo.
    Poser RG; Sirotnak FM; Chello PL
    Cancer Res; 1981 Nov; 41(11 Pt 1):4441-6. PubMed ID: 6171339
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.