BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 6193685)

  • 1. In vitro methotrexate polyglutamate synthesis by rat liver folylpolyglutamate synthetase and inhibition by bromosulfophthalein.
    McGuire JJ; Hsieh P; Coward JK; Bertino JR
    Adv Exp Med Biol; 1983; 163():199-214. PubMed ID: 6193685
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzymatic synthesis of polyglutamate derivatives of 7-hydroxymethotrexate.
    McGuire JJ; Hsieh P; Bertino JR
    Biochem Pharmacol; 1984 Apr; 33(8):1355-61. PubMed ID: 6201178
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Folypolyglutamate synthetase from beef liver: assay, stabilization, and characterization.
    Pristupa ZB; Vickers PJ; Sephton GB; Scrimgeour KG
    Can J Biochem Cell Biol; 1984 Jun; 62(6):495-506. PubMed ID: 6205735
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of folylpolyglutamate synthetase in the regulation of methotrexate polyglutamate formation in H35 hepatoma cells.
    Johnson TB; Nair MG; Galivan J
    Cancer Res; 1988 May; 48(9):2426-31. PubMed ID: 2451560
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The kinetics of methotrexate polyglutamation in human breast cancer cells.
    Morrison PF; Allegra CJ
    Arch Biochem Biophys; 1987 May; 254(2):597-610. PubMed ID: 2437860
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Folate analogues as substrates of mammalian folylpolyglutamate synthetase.
    Schoo MM; Pristupa ZB; Vickers PJ; Scrimgeour KG
    Cancer Res; 1985 Jul; 45(7):3034-41. PubMed ID: 3873989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytotoxicity, uptake, polyglutamate formation, and antileukemic effects of 8-deaza analogues of methotrexate and aminopterin in mice.
    Kuehl M; Brixner DI; Broom AD; Avery TL; Blakley RL
    Cancer Res; 1988 Mar; 48(6):1481-8. PubMed ID: 2449950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS; Galivan J; Wright JE; Rosowsky A
    Mol Pharmacol; 1994 Apr; 45(4):783-91. PubMed ID: 7514264
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human liver folylpolyglutamate synthetase: biochemical characterization and interactions with folates and folate antagonists.
    Clarke L; Waxman DJ
    Arch Biochem Biophys; 1987 Aug; 256(2):585-96. PubMed ID: 3619447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM
    Cancer Res; 1977 Feb; 37(2):408-12. PubMed ID: 832265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

  • 12. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS; Gorlick R; Tong WP; Lin S; Steinherz P; Bertino JR
    Oncol Res; 1997; 9(5):259-63. PubMed ID: 9306433
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Folylpolyglutamate synthetase activities of Neurospora crassa: nature of products formed by soluble and particulate enzymes in the wild type and polyglutamate-deficient mutants.
    Cossins EA; Chan PY
    Adv Exp Med Biol; 1983; 163():183-97. PubMed ID: 6193684
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DL-beta,beta-difluoroglutamic acid mediates position-dependent enhancement or termination of pteroylpoly(gamma-glutamate) synthesis catalyzed by folylpolyglutamate synthetase.
    McGuire JJ; Hart BP; Haile WH; Rhee MS; Galivan J; Coward JK
    Arch Biochem Biophys; 1995 Aug; 321(2):319-28. PubMed ID: 7646057
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells.
    Schilsky RL; Ordway FS
    Cancer Chemother Pharmacol; 1985; 15(3):272-7. PubMed ID: 2414022
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formation of methotrexate polyglutamates in rat hepatocytes.
    Gewirtz DA; White JC; Randolph JK; Goldman ID
    Cancer Res; 1979 Aug; 39(8):2914-8. PubMed ID: 455278
    [TBL] [Abstract][Full Text] [Related]  

  • 17. gamma-Fluoromethotrexate: synthesis and biological activity of a potent inhibitor of dihydrofolate reductase with greatly diminished ability to form poly-gamma-glutamates.
    Galivan J; Inglese J; McGuire JJ; Nimec Z; Coward JK
    Proc Natl Acad Sci U S A; 1985 May; 82(9):2598-602. PubMed ID: 2581252
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of methotrexate polyglutamates in methotrexate- and sequential methotrexate-5-fluorouracil-mediated cell kill.
    McGuire JJ; Mini E; Hsieh P; Bertino JR
    Cancer Res; 1985 Dec; 45(12 Pt 1):6395-400. PubMed ID: 2415244
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates.
    Cowan KH; Jolivet J
    J Biol Chem; 1984 Sep; 259(17):10793-800. PubMed ID: 6206061
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Folate analog nonsubstrates and inhibitors of folylpolyglutamate synthetase as potential cancer chemotherapy drugs.
    McGuire JJ; Piper JR; Coward JK; Galivan J
    NCI Monogr; 1987; (5):139-44. PubMed ID: 2448652
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.