BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 6193689)

  • 1. Studies on the in vivo synthesis of methotrexate polyglutamates and their efflux properties in normal, proliferative, and neoplastic mouse tissues.
    Poser RG; Sirotnak FM
    Adv Exp Med Biol; 1983; 163():259-74. PubMed ID: 6193689
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo.
    Poser RG; Sirotnak FM; Chello PL
    Cancer Res; 1981 Nov; 41(11 Pt 1):4441-6. PubMed ID: 6171339
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse.
    Samuels LL; Goutas LJ; Priest DG; Piper JR; Sirotnak FM
    Cancer Res; 1986 May; 46(5):2230-5. PubMed ID: 2421872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characteristics of the accumulation of methotrexate polyglutamate derivatives in Ehrlich ascites tumor cells and isolated rat hepatocytes.
    Fry DW; Gewirtz DA; Yalowich JC; Goldman ID
    Adv Exp Med Biol; 1983; 163():215-34. PubMed ID: 6193686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM
    Cancer Res; 1977 Feb; 37(2):408-12. PubMed ID: 832265
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Augmentation of the intracellular levels of polyglutamyl derivatives of methotrexate by vincristine and probenecid in Ehrlich ascites tumor cells.
    Fry DW; Yalowich JC; Goldman ID
    Cancer Res; 1982 Jul; 42(7):2532-6. PubMed ID: 6177396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and retention of methotrexate polyglutamates in Ehrlich ascites carcinoma cells.
    BaliƄska M
    Drugs Exp Clin Res; 1986; 12(6-7):551-4. PubMed ID: 2427298
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced polyglutamylation of aminopterin relative to methotrexate in the Ehrlich ascites tumor cell in vitro.
    Matherly LH; Voss MK; Anderson LA; Fry DW; Goldman ID
    Cancer Res; 1985 Mar; 45(3):1073-8. PubMed ID: 2578870
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. Further characterization and evidence for a simple mobile carrier system with broad specificity for homo- or heteropeptides bearing a C-terminal glutamyl moiety.
    Barrueco JR; O'Leary DF; Sirotnak FM
    J Biol Chem; 1992 Oct; 267(28):19986-91. PubMed ID: 1383199
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells.
    Schilsky RL; Ordway FS
    Cancer Chemother Pharmacol; 1985; 15(3):272-7. PubMed ID: 2414022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retentiveness of methotrexate polyglutamates in cultured L1210 cells. Evidence against a role for mediated plasma membrane transport outward.
    Schlemmer SR; Sirotnak FM
    Biochem Pharmacol; 1993 Mar; 45(6):1261-6. PubMed ID: 7682074
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells.
    Jolivet J; Schilsky RL; Bailey BD; Drake JC; Chabner BA
    J Clin Invest; 1982 Aug; 70(2):351-60. PubMed ID: 6178756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, binding and intracellular retention of methotrexate polyglutamates by cultured human breast cancer cells.
    Schilsky RL; Jolivet J; Bailey BD; Chabner BA
    Adv Exp Med Biol; 1983; 163():247-57. PubMed ID: 6193688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proliferation-dependent cytotoxicity of methotrexate in murine L5178Y leukemia.
    Fernandes DJ; Sur P; Kute TE; Capizzi RL
    Cancer Res; 1988 Oct; 48(20):5638-44. PubMed ID: 2458828
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methotrexate polyglutamate synthesis by cultured human breast cancer cells.
    Schilsky RL; Bailey BD; Chabner BA
    Proc Natl Acad Sci U S A; 1980 May; 77(5):2919-22. PubMed ID: 6156458
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell.
    Seither RL; Rape TJ; Goldman ID
    Biochem Pharmacol; 1989 Mar; 38(5):815-22. PubMed ID: 2467676
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
    Koizumi S; Curt GA; Fine RL; Griffin JD; Chabner BA
    J Clin Invest; 1985 Mar; 75(3):1008-14. PubMed ID: 2579975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of polyglutamates in methotrexate action.
    Wilmanns W; Schalhorn A
    Chemioterapia; 1985 Oct; 4(5):349-53. PubMed ID: 2416481
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue pharmacokinetics, inhibition of DNA synthesis and tumor cell kill after high-dose methotrexate in murine tumor models.
    Sirotnak FM; Donsbach RC; Dorick DM; Moccio DM
    Cancer Res; 1976 Dec; 36(12):4672-8. PubMed ID: 1000510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.