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2. Regulation of thymidylate synthase enzyme synthesis in 5-fluorodeoxyuridine-resistant mouse fibroblasts during the transition from the resting to growing state. Jenh CH; Rao LG; Johnson LF J Cell Physiol; 1985 Jan; 122(1):149-54. PubMed ID: 3155521 [TBL] [Abstract][Full Text] [Related]
3. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies. Jackman AL; Alison DL; Calvert AH; Harrap KR Cancer Res; 1986 Jun; 46(6):2810-5. PubMed ID: 2938731 [TBL] [Abstract][Full Text] [Related]
4. Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells. Berger SH; Jenh CH; Johnson LF; Berger FG Mol Pharmacol; 1985 Nov; 28(5):461-7. PubMed ID: 2932632 [TBL] [Abstract][Full Text] [Related]
5. Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine. Zhang ZG; Malmberg M; Yin MB; Slocum HK; Rustum YM Biochem Pharmacol; 1993 Mar; 45(5):1157-64. PubMed ID: 8461045 [TBL] [Abstract][Full Text] [Related]
7. Human leukemic cells resistant to 5-fluoro-2'-deoxyuridine contain a thymidylate synthetase with lower affinity for nucleotides. Bapat AR; Zarow C; Danenberg PV J Biol Chem; 1983 Apr; 258(7):4130-6. PubMed ID: 6220000 [TBL] [Abstract][Full Text] [Related]
8. Resistance to methotrexate in thymidylate synthetase-deficient mutants of cultured mouse mammary tumor FM3A cells. Ayusawa D; Koyama H; Seno T Cancer Res; 1981 Apr; 41(4):1497-501. PubMed ID: 6452198 [TBL] [Abstract][Full Text] [Related]
9. Resistance of CCRF-CEM cloned sublines to 5-fluorodeoxyuridine associated with enhanced phosphatase activities. Fernandes DJ; Cranford SK Biochem Pharmacol; 1985 Jan; 34(1):125-32. PubMed ID: 3155614 [TBL] [Abstract][Full Text] [Related]
10. The role of thymidylate synthase in the response to fluoropyrimidine-folinic acid combinations. Berger SH; Davis ST; Barbour KW; Berger FG Adv Exp Med Biol; 1988; 244():59-69. PubMed ID: 2977716 [TBL] [Abstract][Full Text] [Related]
11. Genetic variation in thymidylate synthase confers resistance to 5-fluorodeoxyuridine. Hughey CT; Barbour KW; Berger FG; Berger SH Adv Exp Med Biol; 1993; 339():67-76. PubMed ID: 8178730 [TBL] [Abstract][Full Text] [Related]
12. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen. Grem JL; Danenberg KD; Behan K; Parr A; Young L; Danenberg PV; Nguyen D; Drake J; Monks A; Allegra CJ Clin Cancer Res; 2001 Apr; 7(4):999-1009. PubMed ID: 11309351 [TBL] [Abstract][Full Text] [Related]
14. Role of thymidylate synthetase activity in development of methotrexate cytotoxicity. Moran RG; Mulkins M; Heidelberger C Proc Natl Acad Sci U S A; 1979 Nov; 76(11):5924-8. PubMed ID: 160558 [TBL] [Abstract][Full Text] [Related]
15. Transient inhibition of DNA synthesis by 5-fluorodeoxyuridine leads to overexpression of dihydrofolate reductase with increased frequency of methotrexate resistance. Schuetz JD; Gorse KM; Goldman ID; Westin EH J Biol Chem; 1988 Jun; 263(16):7708-12. PubMed ID: 2967290 [TBL] [Abstract][Full Text] [Related]
16. Effects of Mg2+ and adenine nucleotides on thymidylate synthetase from different mouse tumors. Rode W; Jastreboff MM Mol Cell Biochem; 1984; 60(1):73-6. PubMed ID: 6231470 [TBL] [Abstract][Full Text] [Related]
17. Retroviral coexpression of thymidylate synthase and dihydrofolate reductase confers fluoropyrimidine and antifolate resistance. Fantz CR; Shaw D; Moore JG; Spencer HT Biochem Biophys Res Commun; 1998 Feb; 243(1):6-12. PubMed ID: 9473470 [TBL] [Abstract][Full Text] [Related]
18. Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity in gastrointestinal tumor cells. Washtien WL Mol Pharmacol; 1982 May; 21(3):723-8. PubMed ID: 6213845 [TBL] [Abstract][Full Text] [Related]
19. Escherichia coli thymidylate synthase expression protects human cells from the cytotoxic effects of 5-fluorodeoxyuridine more effectively than human thymidylate synthase overexpression. Parsels LA; Kowalski MP; Wagner LM; Parsels JD; Maley F; Maybaum J Cancer Gene Ther; 2000 Aug; 7(8):1179-87. PubMed ID: 10975679 [TBL] [Abstract][Full Text] [Related]
20. Experimental chemotherapy of neuroblastoma. II. Increased thymidylate synthetase activity in a 5-fluorodeoxyuridine-resistant variant of mouse neuroblastoma. Baskin F; Carlin SC; Kraus P; Friedkin M; Rosenberg RN Mol Pharmacol; 1975 Jan; 11(1):105-17. PubMed ID: 123312 [No Abstract] [Full Text] [Related] [Next] [New Search]