133 related articles for article (PubMed ID: 6248643)
1. Oxime and dithiolane derivatives of 5-formyl-2'-deoxyuridine and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition.
Park JS; Chang CT; Schmidt CL; Golander Y; De Clercq E; Descamps J; Mertes MP
J Med Chem; 1980 Jun; 23(6):661-5. PubMed ID: 6248643
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of 5-[(methylthio)methyl]-2'-deoxyuridine, the corresponding sulfoxide and sulfone, and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition.
Schmidt CL; Chang CT; De Clercq E; Descamps J; Mertes MP
J Med Chem; 1980 Mar; 23(3):252-6. PubMed ID: 6245212
[TBL] [Abstract][Full Text] [Related]
3. 5-Cyano-2'-deoxyuridine 5'-phosphate: a potent competitive inhibitor of thymidylate synthetase.
Chang CT; Edwards MW; Torrence PF; Mertes MP
J Med Chem; 1979 Sep; 22(9):1137-9. PubMed ID: 114660
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of 5-selenium-substituted uracil derivatives. Inhibition of thymidylate synthetase by 5-hydroseleno-2'-deoxyuridylate.
Choi S; Kalman TI; Bardos TJ
J Med Chem; 1979 Jun; 22(6):618-21. PubMed ID: 110931
[TBL] [Abstract][Full Text] [Related]
5. Antiviral, antitumor, and thymidylate synthetase inhibition studies of 5-substituted styryl derivatives of 2'-deoxyuridine and their 5'-phosphates.
De Clercq E; Balzarini J; Descamps J; Bigge CF; Chang CT; Kalaritis P; Mertes MP
Biochem Pharmacol; 1981 Mar; 30(5):495-502. PubMed ID: 6261769
[No Abstract] [Full Text] [Related]
6. 5-(alpha-Bromoacetyl)-2'-deoxyuridine 5'-phosphate: an affinity label for thymidylate synthetase.
Brouillette CB; Chang CT; Mertes MP
J Med Chem; 1979 Dec; 22(12):1541-4. PubMed ID: 119854
[TBL] [Abstract][Full Text] [Related]
7. 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate: a possible mechanism-based inhibitor of thymidylate synthetase.
Maggiora L; Chang CT; Hasson ME; Bigge CF; Mertes MP
J Med Chem; 1983 Jul; 26(7):1028-36. PubMed ID: 6408258
[TBL] [Abstract][Full Text] [Related]
8. 5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.
De Clercq E; Descamps J; Huang GF; Torrence PF
Mol Pharmacol; 1978 May; 14(3):422-30. PubMed ID: 661811
[No Abstract] [Full Text] [Related]
9. 5-Nitro-2'-deoxyuridine 5'-monophosphate is a potent irreversible inhibitor of Lactobacillus caesi thymidylate synthetase.
Mertes MP; Chang CT; De Clercq E; Huang GF; Torrence PF
Biochem Biophys Res Commun; 1978 Oct; 84(4):1054-9. PubMed ID: 103545
[No Abstract] [Full Text] [Related]
10. 5-Quinone derivatives of 2'-deoxyuridine 5'-phosphate: inhibition and inactivation of thymidylate synthase, antitumor cell, and antiviral studies.
Al-Razzak LA; Schwepler D; Decedue CJ; Balzarini J; De Clercq E; Mertes MP
J Med Chem; 1987 Feb; 30(2):409-19. PubMed ID: 3027341
[TBL] [Abstract][Full Text] [Related]
11. 5 (alpha-bromoacetyl)-2'=deoxyuridine 5'-phosphate: a mechanism based affinity label for thymidylate synthetase.
Brouillette CB; Chang CT; Mertes MP
Biochem Biophys Res Commun; 1979 Mar; 87(2):613-8. PubMed ID: 109088
[No Abstract] [Full Text] [Related]
12. 5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase.
Balzarini J; De Clercq E; Mertes MP; Shugar D; Torrence PF
Biochem Pharmacol; 1982 Nov; 31(22):3673-82. PubMed ID: 7181950
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of Lactobacillus casei thymidylate synthetase by 5-substituted 2'-deoxyuridylates. Preliminary quantitative structure-activity relationship.
Wataya Y; Santi DV; Hansch C
J Med Chem; 1977 Nov; 20(11):1469-73. PubMed ID: 410930
[No Abstract] [Full Text] [Related]
14. Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.
Santi DV
J Med Chem; 1980 Feb; 23(2):103-11. PubMed ID: 6987403
[No Abstract] [Full Text] [Related]
15. Inhibition of thymidylate synthetase by 5-alkynyl-2'-deoxyuridylates.
Barr PJ; Nolan PA; Santi DV; Robins MJ
J Med Chem; 1981 Dec; 24(12):1385-8. PubMed ID: 6796687
[No Abstract] [Full Text] [Related]
16. Synthesis and antiviral activity of 5-[(cyanomethylene)oxy]-2'-deoxyuridine.
Huang GF; Okada M; De Clercq E; Torrence PF
J Med Chem; 1981 Apr; 24(4):390-3. PubMed ID: 6267280
[TBL] [Abstract][Full Text] [Related]
17. 5-[(4-Methyl-1,2,3,4-tetrahydroquinoxalyl)methyl]-2'-deoxyuridine 5'-phosphate: an analogue of a proposed intermediate in thymidylate synthetase catalysis.
Park JS; Chang CT; Mertes MP
J Med Chem; 1979 Sep; 22(9):1134-7. PubMed ID: 114659
[TBL] [Abstract][Full Text] [Related]
18. 5-O-Alkylated derivatives of 5-hydroxy-2'-deoxyuridine as potential antiviral agents. Anti-herpes activity of 5-propynyloxy-2'-deoxyuridine.
Torrence PF; Spencer JW; Bobst AM
J Med Chem; 1978 Feb; 21(2):228-31. PubMed ID: 202709
[TBL] [Abstract][Full Text] [Related]
19. 5-Nitro-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase.
Matsuda A; Wataya Y; Santi DV
Biochem Biophys Res Commun; 1978 Oct; 84(3):654-9. PubMed ID: 102324
[No Abstract] [Full Text] [Related]
20. Interaction of 5-ethynyl-2'-deoxyuridylate with thymidylate synthetase.
Danenberg PV; Bhatt RS; Kundu NG; Danenberg K; Heidelberger C
J Med Chem; 1981 Dec; 24(12):1537-40. PubMed ID: 6796692
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
