These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 6268770)

  • 1. Identification and determination of 11-oxo-delta8-tetrahydrocannabinol as an intermediate metabolite of delta8-tetrahydrocannabinol in the mouse brain and liver.
    Watanabe K; Yamamoto I; Oguri K; Yoshimura H
    J Pharmacobiodyn; 1980 Dec; 3(12):686-91. PubMed ID: 6268770
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Monkey hepatic microsomal alcohol oxygenase: purification and characterization of a cytochrome P450 enzyme catalyzing the stereoselective oxidation of 7alpha- and 7beta-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol.
    Matsunaga T; Iwawaki Y; Komura A; Watanabe K; Kageyama T; Yamamoto I
    Biol Pharm Bull; 2002 Jan; 25(1):42-7. PubMed ID: 11824554
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of microsomal alcohol oxygenase catalyzing the oxidation of 7-hydroxy-delta 8-tetrahydrocannabinol to 7-oxo-delta 8-tetrahydrocannabinol in rat liver.
    Matsunaga T; Shibayama K; Higuchi S; Tanaka H; Watanabe K; Yamamoto I
    Biol Pharm Bull; 2000 Jan; 23(1):43-6. PubMed ID: 10706409
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and determination of 8 alpha, 9 alpha-epoxyhexahydrocannabinol as a metabolite of delta 8-tetrahydrocannabinol of mice in vitro.
    Narimatsu S; Watanabe K; Yamamoto I; Yoshimura H
    Xenobiotica; 1982 Sep; 12(9):561-5. PubMed ID: 6297175
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stimulatory effects of testosterone and progesterone on the NADH- and NADPH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol in monkey liver microsomes.
    Funahashi T; Tanaka Y; Yamaori S; Kimura T; Matsunaga T; Ohmori S; Kageyama T; Yamamoto I; Watanabe K
    Drug Metab Pharmacokinet; 2005 Oct; 20(5):358-67. PubMed ID: 16272754
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of hepatic microsomal oxidation of 11-hydroxy-delta 8-tetrahydrocannabinol to 11-oxo-delta 8-tetrahydrocannabinol. Evidence for hydration of the aldehyde formed.
    Watanabe K; Matsunaga T; Narimatsu S; Yamamoto I; Yoshimura H
    J Pharmacobiodyn; 1992 Jun; 15(6):311-7. PubMed ID: 1331394
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic disposition of delta 8-tetrahydrocannabinol and its active metabolites, 11-hydroxy-delta 8-tetrahydrocannabinol and 11-oxo-delta 8-tetrahydrocannabinol, in mice.
    Watanabe K; Yamamoto I; Oguri K; Yoshimura H
    Drug Metab Dispos; 1981; 9(3):261-4. PubMed ID: 6113937
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Competitive inhibition of delta8-tetrahydrocannabinol and its active metabolites for cannabinoid receptor binding.
    Yamamoto I; Kimura T; Kamei A; Yoshida H; Watanabe K; Ho IK; Yoshimura H
    Biol Pharm Bull; 1998 Apr; 21(4):408-10. PubMed ID: 9586583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigation of phase II metabolism of 11-hydroxy-Δ-9-tetrahydrocannabinol and metabolite verification by chemical synthesis of 11-hydroxy-Δ-9-tetrahydrocannabinol-glucuronide.
    Hassenberg C; Clausen F; Hoffmann G; Studer A; Schürenkamp J
    Int J Legal Med; 2020 Nov; 134(6):2105-2119. PubMed ID: 32808050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of a Delta-9-Tetrahydrocannabinol Carboxylic Acid (Δ9-THC-COOH) Immunoassay and a Gas Chromatography-Mass Spectrometry (GC-MS) Method for the Detection of Delta-8-Tetrahydrocannabinol Carboxylic Acid (Δ8-THC-COOH).
    Baird SN; Frazee CC; Garg U
    J Appl Lab Med; 2023 Jul; 8(4):665-673. PubMed ID: 37071885
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and pharmacological activity of a phosphate ester of delta8-tetrahydrocannabinol.
    Yoshimura H; Watanabe K; Oguri K; Fujiwara M; Ueki S
    J Med Chem; 1978 Oct; 21(10):1079-81. PubMed ID: 569207
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serum and Urine Quantification of Delta-8 and Delta-9 Tetrahydrocannabinol Carboxylic Acid Using Gas Chromatography-Mass Spectrometry.
    Shell S; Clinton Frazee C; Garg U
    Methods Mol Biol; 2024; 2737():153-159. PubMed ID: 38036819
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of repeated administration of 11-hydroxy-delta 8-tetrahydrocannabinol, an active metabolite of delta 8-tetrahydrocannabinol, on the hepatic microsomal drug-metabolizing enzyme system of mice.
    Watanabe K; Arai M; Narimatsu S; Yamamoto I; Yoshimura H
    Biochem Pharmacol; 1986 Jun; 35(11):1861-5. PubMed ID: 3013200
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Marihuana-like activity of new synthetic tetrahydrocannabinols.
    Martin BR; Dewey WL; Harris LS; Beckner J
    Pharmacol Biochem Behav; 1975; 3(5):849-53. PubMed ID: 1208625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-delta(8)-tetrahydrocannabinol in human liver microsomes.
    Matsunaga T; Kishi N; Higuchi S; Watanabe K; Ohshima T; Yamamoto I
    Drug Metab Dispos; 2000 Nov; 28(11):1291-6. PubMed ID: 11038155
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improved and validated method for the determination of Delta(9)-tetrahydrocannabinol (THC), 11-hydroxy-THC and 11-nor-9-carboxy-THC in serum, and in human liver microsomal preparations using gas chromatography-mass spectrometry.
    Steinmeyer S; Bregel D; Warth S; Kraemer T; Moeller MR
    J Chromatogr B Analyt Technol Biomed Life Sci; 2002 Jun; 772(2):239-48. PubMed ID: 12007768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Major cytochrome P450 enzyme responsible for oxidation of secondary alcohols to the corresponding ketones in mouse hepatic microsomes. Oxidation of 7-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol.
    Matsunaga T; Kishi N; Tanaka H; Watanabe K; Yoshimura H; Yamamoto I
    Drug Metab Dispos; 1998 Oct; 26(10):1045-7. PubMed ID: 9763413
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Delta(9)-tetrahydrocannabinol, 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol in human plasma after controlled oral administration of cannabinoids.
    Goodwin RS; Gustafson RA; Barnes A; Nebro W; Moolchan ET; Huestis MA
    Ther Drug Monit; 2006 Aug; 28(4):545-51. PubMed ID: 16885723
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol.
    Handrick GR; Duffley RP; Lambert G; Murphy JG; Dalzell HC; Howes JF; Razdan RK; Martin BR; Harris LS; Dewey WL
    J Med Chem; 1982 Dec; 25(12):1447-50. PubMed ID: 6296389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of n-hexyl-homologues of delta-8-tetrahydrocannabinol and delta-9-tetrahydrocannabinol in the mouse.
    Brown NK; Harvey DJ
    Eur J Drug Metab Pharmacokinet; 1988; 13(3):165-76. PubMed ID: 2853671
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.