BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 6285172)

  • 1. Differential phosphorylation of (E)-5-(2-bromovinyl)-2'-deoxyuridine monophosphate by thymidylate kinases from herpes simplex viruses types 1 and 2 and varicella zoster virus.
    Fyfe JA
    Mol Pharmacol; 1982 Mar; 21(2):432-7. PubMed ID: 6285172
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Altered thymidine-thymidylate kinases from strains of herpes simplex virus with modified drug sensitivities to acyclovir and (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Fyfe JA; McKee SA; Keller PM
    Mol Pharmacol; 1983 Sep; 24(2):316-23. PubMed ID: 6310366
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative metabolism of E-5-(2-bromovinyl)-2'-deoxyuridine and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in herpes simplex virus-infected cells.
    Ayisi NK; Wall RA; Wanklin RJ; Machida H; De Clercq E; Sacks SL
    Mol Pharmacol; 1987 Apr; 31(4):422-9. PubMed ID: 3472064
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase.
    Grignet-Debrus C; Cool V; Baudson N; Degrève B; Balzarini J; De Leval L; Debrus S; Velu T; Calberg-Bacq CM
    Cancer Gene Ther; 2000 Feb; 7(2):215-23. PubMed ID: 10770629
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetics of the interaction of monophosphates of the antiviral nucleosides 2'-fluoro-1-beta-D-arabinofuranosylpyrimidine and (E)-5-(2-bromovinyl)-2'-deoxyuridine with thymidylate kinases from Vero cells and herpes simplex virus types 1 and 2.
    Chen MS; Amico LA; Speelman DJ
    Antimicrob Agents Chemother; 1984 Nov; 26(5):778-80. PubMed ID: 6083755
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies.
    Spadari S; Ciarrocchi G; Focher F; Verri A; Maga G; Arcamone F; Iafrate E; Manzini S; Garbesi A; Tondelli L
    Mol Pharmacol; 1995 Jun; 47(6):1231-8. PubMed ID: 7603465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective inhibition of the proliferation of herpes simplex virus type 1 thymidine kinase gene-transformed murine mammary FM3A carcinoma cells by (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
    Balzarini J; De Clercq E; Ayusawa D; Shimizu K; Seno T
    Nucleic Acids Symp Ser; 1985; (16):283-6. PubMed ID: 3003708
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of a varicella-zoster virus variant with altered thymidine kinase activity.
    Shigeta S; Mori S; Yokota T; Konno K; De Clercq E
    Antimicrob Agents Chemother; 1986 Jun; 29(6):1053-8. PubMed ID: 3015014
    [TBL] [Abstract][Full Text] [Related]  

  • 9. (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
    De Clercq E
    Med Res Rev; 2005 Jan; 25(1):1-20. PubMed ID: 15389733
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential metabolism of (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVDU) by equine herpesvirus type 1- and herpes simplex virus-infected cells.
    Kit S; Ichimura H; De Clercq E
    Antiviral Res; 1987 Aug; 8(1):41-51. PubMed ID: 2825591
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antiviral activity of the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    De Clercq E; Descamps J; Balzarini J; Fukui T; Allaudeen HS
    Biochem J; 1983 May; 211(2):439-45. PubMed ID: 6307280
    [TBL] [Abstract][Full Text] [Related]  

  • 12. (E)-5-(2-bromovinyl)-2'-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase--expressing cells.
    Hamel W; Zirkel D; Mehdorn HM; Westphal M; Israel MA
    Cancer Gene Ther; 2001 May; 8(5):388-96. PubMed ID: 11477459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential affinities of 5-(2-halogenovinyl)-2'-deoxyuridines for deoxythymidine kinases of various origins.
    Cheng YC; Dutschman G; De Clercq E; Jones AS; Rahim SG; Verhelst G; Walker RT
    Mol Pharmacol; 1981 Jul; 20(1):230-3. PubMed ID: 6270535
    [No Abstract]   [Full Text] [Related]  

  • 14. (E)-5-(2-bromovinyl)uridine requires phosphorylation by the herpes simplex virus (type 1)-induced thymidine kinase to express its antiviral activity.
    Bernaerts R; Desgranges C; De Clercq E
    Biochem Pharmacol; 1989 Jun; 38(12):1955-61. PubMed ID: 2545207
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preferential inhibition of 5-trifluoromethyl-2'-deoxyuridine phosphorylation by 5'-amino-5'-deoxythymidine in uninfected versus herpes simplex virus-infected cells.
    Fischer PH; Murphy DG; Kawahara R
    Mol Pharmacol; 1983 Jul; 24(1):90-6. PubMed ID: 6408395
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Incorporation of (E)-5-(2-iodovinyl)-2'-deoxyuridine into deoxyribonucleic acids of varicella-zoster virus (TK+ and TK- strains)-infected cells.
    Yokota T; Konno K; Shigeta S; Verbruggen A; De Clercq E
    Mol Pharmacol; 1987 May; 31(5):493-9. PubMed ID: 3033468
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleoside analogs as non-substrate inhibitors of herpes simplex viruses thymidine kinase.
    Focher F; Sandoli D; Hildebrand C; Sangalli S; Ciarrocchi G; Rebuzzini A; Pedrali-Noy G; Manservigi R; Wright G; Brown N
    Methods Find Exp Clin Pharmacol; 1989 Sep; 11(9):577-82. PubMed ID: 2555637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential binding affinities of sugar-modified derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine for herpes simplex virus-induced and human cellular deoxythymidine kinases.
    Zou FC; Dutschman GE; De Clercq E; Cheng YC
    Biochem Pharmacol; 1984 Jun; 33(11):1797-800. PubMed ID: 6329218
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The relationship between incorporation of E-5-(2-Bromovinyl)-2'-deoxyuridine into herpes simplex virus type 1 DNA with virus infectivity and DNA integrity.
    Mancini WR; De Clercq E; Prusoff WH
    J Biol Chem; 1983 Jan; 258(2):792-5. PubMed ID: 6296080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Incorporation of E-5-(2-halovinyl)-2'-deoxyuridines into deoxyribonucleic acids of herpes simplex virus type 1-infected cells.
    Allaudeen HS; Chen MS; Lee JJ; De Clercq E; Prusoff WH
    J Biol Chem; 1982 Jan; 257(2):603-6. PubMed ID: 6274855
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.