These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution. Shoelson S; Fickova M; Haneda M; Nahum A; Musso G; Kaiser ET; Rubenstein AH; Tager H Proc Natl Acad Sci U S A; 1983 Dec; 80(24):7390-4. PubMed ID: 6424111 [TBL] [Abstract][Full Text] [Related]
4. Familial hyperproinsulinemia. Two cohorts secreting indistinguishable type II intermediates of proinsulin conversion. Robbins DC; Shoelson SE; Rubenstein AH; Tager HS J Clin Invest; 1984 Mar; 73(3):714-9. PubMed ID: 6368587 [TBL] [Abstract][Full Text] [Related]
5. Two mutant forms of human insulin. Structural consequences of the substitution of invariant B24- or B25-phenylalanine by leucine. Wollmer A; Strassburger W; Glatter U; Dodson GG; McCall M; Gattner HG; Danho W; Brandenburg D; Rittel W Hoppe Seylers Z Physiol Chem; 1981 Jun; 362(6):581-91. PubMed ID: 7024084 [TBL] [Abstract][Full Text] [Related]
6. Two unrelated patients with familial hyperproinsulinemia due to a mutation substituting histidine for arginine at position 65 in the proinsulin molecule: identification of the mutation by direct sequencing of genomic deoxyribonucleic acid amplified by polymerase chain reaction. Barbetti F; Raben N; Kadowaki T; Cama A; Accili D; Gabbay KH; Merenich JA; Taylor SI; Roth J J Clin Endocrinol Metab; 1990 Jul; 71(1):164-9. PubMed ID: 2196279 [TBL] [Abstract][Full Text] [Related]
7. Structural determinants of ligand recognition by type I insulin-like growth factor receptors: use of semisynthetic insulin analog probes. Cara JF; Nakagawa SH; Tager HS Endocrinology; 1988 Jun; 122(6):2881-7. PubMed ID: 2967179 [TBL] [Abstract][Full Text] [Related]
8. NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition. Weiss MA; Frank BH; Khait I; Pekar A; Heiney R; Shoelson SE; Neuringer LJ Biochemistry; 1990 Sep; 29(36):8389-401. PubMed ID: 2252901 [TBL] [Abstract][Full Text] [Related]
9. Role of the phenylalanine B25 side chain in directing insulin interaction with its receptor. Steric and conformational effects. Nakagawa SH; Tager HS J Biol Chem; 1986 Jun; 261(16):7332-41. PubMed ID: 3519607 [TBL] [Abstract][Full Text] [Related]
10. A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto). Yano H; Kitano N; Morimoto M; Polonsky KS; Imura H; Seino Y J Clin Invest; 1992 Jun; 89(6):1902-7. PubMed ID: 1601997 [TBL] [Abstract][Full Text] [Related]
11. Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor. Xu B; Hu SQ; Chu YC; Huang K; Nakagawa SH; Whittaker J; Katsoyannis PG; Weiss MA Biochemistry; 2004 Jul; 43(26):8356-72. PubMed ID: 15222748 [TBL] [Abstract][Full Text] [Related]
12. Biochemical and clinical implications of proinsulin conversion intermediates. Given BD; Cohen RM; Shoelson SE; Frank BH; Rubenstein AH; Tager HS J Clin Invest; 1985 Oct; 76(4):1398-405. PubMed ID: 3902891 [TBL] [Abstract][Full Text] [Related]
13. Structural integrity of the B24 site in human insulin is important for hormone functionality. Žáková L; Kletvíková E; Veverka V; Lepsík M; Watson CJ; Turkenburg JP; Jirácek J; Brzozowski AM J Biol Chem; 2013 Apr; 288(15):10230-40. PubMed ID: 23447530 [TBL] [Abstract][Full Text] [Related]
14. Diabetes mellitus caused by mutations in human insulin: analysis of impaired receptor binding of insulins Wakayama, Los Angeles and Chicago using pharmacoinformatics. Islam MA; Bhayye S; Adeniyi AA; Soliman ME; Pillay TS J Biomol Struct Dyn; 2017 Mar; 35(4):724-737. PubMed ID: 26950281 [TBL] [Abstract][Full Text] [Related]
15. Three mutant insulins in man. Shoelson S; Haneda M; Blix P; Nanjo A; Sanke T; Inouye K; Steiner D; Rubenstein A; Tager H Nature; 1983 Apr; 302(5908):540-3. PubMed ID: 6339950 [TBL] [Abstract][Full Text] [Related]
16. Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. Shoelson SE; Polonsky KS; Zeidler A; Rubenstein AH; Tager HS J Clin Invest; 1984 May; 73(5):1351-8. PubMed ID: 6371057 [TBL] [Abstract][Full Text] [Related]
17. INS-gene mutations: from genetics and beta cell biology to clinical disease. Liu M; Sun J; Cui J; Chen W; Guo H; Barbetti F; Arvan P Mol Aspects Med; 2015 Apr; 42():3-18. PubMed ID: 25542748 [TBL] [Abstract][Full Text] [Related]
19. Secretion and processing of insulin precursors in yeast. Thim L; Hansen MT; Norris K; Hoegh I; Boel E; Forstrom J; Ammerer G; Fiil NP Proc Natl Acad Sci U S A; 1986 Sep; 83(18):6766-70. PubMed ID: 3529091 [TBL] [Abstract][Full Text] [Related]
20. Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin. Tager H; Thomas N; Assoian R; Rubenstein A; Saekow M; Olefsky J; Kaiser ET Proc Natl Acad Sci U S A; 1980 Jun; 77(6):3181-5. PubMed ID: 6997872 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]